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Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test.
The form that is purified from pig pituitary glands is known as corticotropin is a medication and naturally occurring polypeptide tropic hormone produced and secreted by the anterior pituitary gland.
The form that is made synthetically is tetracosactide, also known as synacthen, tetracosactrin and cosyntropin. It consists of the first 24 amino acids of ACTH and retains full function of the parent peptide. Tetracosactide stimulates the release of corticosteroids such as cortisol from the adrenal glands, and is used for the ACTH stimulation test to assess adrenal gland function.
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