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The quantitative insulin sensitivity check index is derived using the inverse of the sum of the logarithms of the fasting insulin and fasting glucose:

This index correlates well with glucose clamp studies , and is useful for measuring insulin sensitivity , which is the inverse of insulin resistance. It has the advantage of that it can be obtained from a fasting blood sample, and is the preferred method for certain types of clinical research.

Values typically associated with the QUICKI calculation for insulin resistance in humans fall broadly within a range between 0.45 for unusually healthy individuals and 0.30 in diabetics. So lower numbers reflect greater insulin resistance.

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