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Alabama rot or cutaneous and renal glomerular vasculopathy is an often fatal condition in dogs. It was first identified in the US in the 1980s in greyhounds. The initial symptoms are skin lesions on the legs, chest and abdomen followed by renal involvement.

In November 2012 the first cases were suspected in the UK. In January 2014, the outbreak in England was identified as having the same or similar histological and clinical findings as Alabama rot, though this could not be classified as Alabama Rot as the histological results from the UK lacked the relation to E. coli that was present in all the cases in the US, although a wide range of breeds were affected. The suspected disease has been possibly identified across England and Wales, with a case being reported as far north as North Yorkshire in March 2015. A UK map posted online shows confirmed and unconfirmed cases of CRGV since December 2012. In May 2017 it was reported that 98 suspected deaths from the disease have occurred in the UK, including 15 in 2017. Local residents report 6 vet reported deaths in the Rivington area in Winter 2017/18 with 2 dogs still to have autopsies. One ongoing local study in 2018 finds a lethal outbreak following the escape of wormed deer in Adlington, England, of deer deemed unfit for human food. With no wormer maintained, bacteria or parasites could have spread naturally especially towards predatory breeds.

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