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Doctor of Osteopathic Medicine is a medical degree conferred by the 38 osteopathic medical schools in the United States. DO and Doctor of Medicine degrees are equivalent: a DO graduate may become licensed as a physician and thus have full medical and surgical practicing rights in all 50 US states. As of 2021, there were 168,701 osteopathic physicians and medical students in DO programs across the United States. Osteopathic medicine emerged historically from osteopathy, but has become a distinct profession.

As of 2014, more than 28% of all US medical students were DO students. The curricula at DO-granting medical schools are equivalent to those at MD-granting medical schools, which focus the first two years on the biomedical and clinical sciences, then two years on core clinical training in the clinical specialties.

One notable difference between DO and MD training is that DOs spend an additional 300–500 hours to study a set of hands-on manipulation of the human musculoskeletal system along with learning conventional Western medicine and surgery like their MD peers.

Upon completing medical school, a DO graduate may enter an internship or residency training program, which may be followed by fellowship training. DO graduates attend the same graduate medical education programs as their MD counterparts.

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