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Time-domain diffuse optics or time-resolved functional near-infrared spectroscopy is a branch of functional near-Infrared spectroscopy which deals with light propagation in diffusive media. There are three main approaches to diffuse optics namely continuous wave , frequency domain and time-domain. Biological tissue in the range of red to near-infrared wavelengths are transparent to light and can be used to probe deep layers of the tissue thus enabling various in vivo applications and clinical trials.
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