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Acute myelomonocytic leukemia is a form of acute myeloid leukemia that involves a proliferation of CFU-GM myeloblasts and monoblasts. AMML occurs with a rapid increase amount in white blood cell count and is defined by more than 20% of myeloblast in the bone marrow. It is classified under "M4" in the French-American-British classification. It is classified under "AML, not otherwise classified" in the WHO classification.
Translocations have been observed. Progression from myelodysplastic syndrome has been reported.
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