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Congenital ichthyosiform erythroderma , also known as nonbullous congenital ichthyosiform erythroderma, is a rare type of the ichthyosis family of skin diseases which occurs in 1 in 200,000 to 300,000 births. CIE comes under the umbrella term autosomal recessive congenital ichthyosis , which include non-syndromic congenital ichthyoses such as harlequin ichthyosis and lamellar ichthyosis.
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