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Topical prednisolone is a type of glucocorticoid, mainly used in the ophthalmic pathway as eye drops in numerous eye conditions, such as corneal injuries caused by chemicals, burns and alien objects, inflammation of the eyes, mild to moderate non-infectious allergies, disorders of the eyelid, conjunctiva or sclera, ocular inflammation caused by operation and optic neuritis. Some side effects include glaucoma, blurring of vision, eye discomfort, impaired recovery of injured site, scarring of the optic nerve, clouding of lenses and urticaria. However, their prevalence is not known.
Prednisolone eye drops are contraindicated in individuals who develop hypersensitivity reactions against prednisolone, or individuals with the current conditions, such as tuberculosis of the eye, shingles affecting the eye, raised intraocular pressure, eye infection caused by fungus, diabetes.
Prednisolone eye drops can be either formulated in solutions or suspensions. Solutions, in general, have better performance than suspensions regardless of the amount of time shaken, as suspensions fail to dispense the same amount of corticosteroids each time. Suspension forms are less suitable for corticosteroid delivery into the eye.
The effects of prednisolone may be greater when used in children under 6 years of age. Women who are pregnant are not recommended to consume this product unless the benefits outweigh the risk. Those who are breastfeeding are not suggested to use this product since there is insufficient evidence to prove its safeness. Individuals who are wearing contact lenses should remove them before administering the eye drop.