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Familial Danish Dementia is a rare neurodegenerative disease that is mostly hereditary and resembles Alzheimer's. The condition was first reported in the Djursland peninsula in Denmark.
It is one of the two types of hereditary cerebral amyloid angiopathy alongside familial British dementia.
The disorder is histopathologically characterized by serve cerebral amyloid angiopathy with neurofibrillary tangle deposition in the limbic system and the neocortex. It is also neuropathologically characterized by diffuse atrophy of cerebellum, cranial nerves, and the spinal cord.
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