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Delta ratio, or "delta-delta", is a formula that can be used to assess elevated anion gap metabolic acidosis and to evaluate whether a mixed acid–base disorder is present. The anion gap without potassium is calculated first and if a metabolic acidosis is present, results in either a high anion gap metabolic acidosis or a normal anion gap acidosis. A low anion gap is usually an oddity of measurement, rather than a clinical concern.
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