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Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules.

Formation of a granuloma is a common tissue response to a range of foreign bodies. Silicone can be directly injected into tissue as part of a cosmetic procedure or it can leak from silicone implants. The formation and consequences of silicon-induced granulomas is not well described or understood. The extent of damage that they cause is controversial.

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