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The National Organ Transplant Act of 1984 is an Act of the United States Congress which established the framework for the U.S. organ transplant system. The act clarified the property rights of human organs from deceased individuals and created a public-private partnership known as the Organ Procurement and Transplantation Network , which was empowered to manage organ allocation on a national basis.

Since the initial network contract was finalized in 1986, United Network for Organ Sharing has served as the OPTN under contract with the U.S. Department of Health and Human Services. OPTN policies are developed by a broad community that includes donation and transplant clinicians and professionals. NOTA and subsequent federal regulation call on the OPTN to emphasize fair and equitable patient access to transplantation, as well as reliance on objective medical evidence and adaptability to evolution in clinical treatment and scientific understanding.

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