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The intracytoplasmic morphologically selected sperm injection is a laboratory technique used for In Vitro Fertilisation treatments. High quality sperms are injected into the egg for fertilization, it is an advanced version of ICSI.A high powered microscope is used to pick out and the best sperm cells which are then used in a traditional ICSI protocol. In ICSI a magnification of x400 is used, while in IMSI an amplification of 6000 to 10,000 is used, at least 15 times greater. This allows the sperm to be examined in greater detail, including the nucleus which contains the sperm's genetic material. Use of this method has resulted in higher pregnancy and delivery rates and lower abortion rates. IMSI is a good choice for anyone who has failed IVF cycles in the past, and for couples who have a component of male infertility.