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Radiation retinopathy is damage to retina due to exposure to ionizing radiation. Radiation retinopathy has a delayed onset, typically after months or years of radiation, and is slowly progressive. In general, radiation retinopathy is seen around 18 months after treatment with external-beam radiation and with brachytherapy. The time of onset of radiation retinopathy is between 6 months to 3 years.

An exposure to doses of 30-35 grays or more is usually required to induce clinical symptoms, however, retinopathy may develop after as little as 15 Gy of external-beam radiation. A reported safe dose is 30 Gy : 10 Gy per week in five fractions of 2 Gy.

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