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Estradiol/levonorgestrel , sold under brand name Climara Pro, is a combination of estradiol and levonorgestrel which is used in menopausal hormone therapy. It is a 22-cm transdermal patch containing 4.4 mg estradiol and 1.39 mg levonorgestrel and delivers 45 μg/day estradiol and 15 μg/day levonorgestrel. E2/LNG was approved for medical use in the United States in 2003.
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