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Stem cell fat grafting is autotransplantation of adipose-derived stem cells extracted from fat-abundant donor sites to other areas such as the face, breast, and hip to reconstruct the operative areas into desirable shapes. ADSCs are multipotent stem cells found in adipose tissues, displaying similar differentiation potentials to bone marrow-derived mesenchymal stem cells.
The discovery of ADSCs has brought great advances to the field of regenerative medicine and aesthetic procedures.Whilst the use of embryonic stem cells was reconsidered for ethical reasons, ADSCs got attention from plastic surgeons owing to their characteristics such as pluripotent differentiation potential, paracrine activities, immunomodulatory functions, and homing effect.
Regardless of the numerous benefits, there are few side effects and oncology safety issues The rising investment in stem cell cosmetic therapy reflects the high expectation and demands especially in South Korea. Further research on the effectiveness of ADSCs grafting proposed that the aftermath of the therapy can be affected by the quality of stem cells and diet by fostering adequate conditions for stem cell growth and sufficient consumption of nutrients.