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Seminal fluid proteins or accessory gland proteins are one of the non-sperm components of semen. In many animals with internal fertilization, males transfer a complex cocktail of proteins in their semen to females during copulation. These seminal fluid proteins often have diverse, potent effects on female post-mating phenotypes. SFPs are produced by the male accessory glands.

Seminal fluid proteins frequently show evidence of elevated evolutionary rates and are often cited as an example of sexual conflict.

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