1. Duodenum
  2. Lower oesophageal sphincter
  3. Diaphragm
  4. Pylorus
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1 Answers

Option 2 : Lower oesophageal sphincter

Concept:

  • Gastro-esophageal reflux disease -> It is a disease characterised by frequent regurgitation of the stomach contents into the esophagus.
  • The acidic nature of the gastric reflux often irritates the esophageal epithelium.
  • Lifestyle changes can be done to manage and prevent GERD.

Explanation:

  • Once the food is ingested from the mouth through peristalsis, the esophageal sphincter closes and prevents the movement of the food back towards the oral cavity.
  • In case of GERD, gastric reflux regurgitates into the esophagus and damages the esophageal lining.
  • Improper functioning of the lower esophageal sphincter leads to GERD.

  • Duodenum is not affected in GERD as it lies below the stomach in the alimentary canal.
  • Diaphragm is not affected in GERD
  • Pylorus is not affected by GERD.
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