Patau’s syndrome involves abnormality in which chromosome?

Option 1 : 13

The correct answer is Option 1, i.e 13.

• Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13.
• The extra genetic material disrupts normal development, causing multiple and complex organ defects.
• Each cell normally contains 23 pairs of chromosomes, which carry the genes you inherit from your parents. 
• But a baby with Patau's syndrome has 3 copies of chromosome 13, instead of 2.
• This severely disrupts normal development and, in many cases, results in miscarriage, stillbirth or the baby dying shortly after birth.
• Babies with Patau's syndrome grow slowly in the womb and have a low birth weight, along with a number of other serious medical problems.