1. favourable
  2. indifferent
  3. unfortunate
  4. opposed
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Answer: Option 4

Favourable : expressing approval. Indifferent : having no particular interest or sympathy; unconcerned. Unfortunate : having or marked by bad fortune; unlucky. Opposed : anxious to prevent or put an end to; disagreeing with. Adverse : preventing success or development; harmful; unfavourable. Synonym of Adverse is Opposed

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