1. 1939
  2. 1958
  3. 1981
  4. 1978
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Answer: Option 4

In 1978 first test tube baby - Louise Brown was born. Louise Joy Brown is best known as the world's first "test-tube baby." Her birth by Caesarian section shortly before midnight on July 25, 1978, at Oldham General Hospital in England, made headlines around the world.

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