Vaxigrip Tetra IM Injection

Introduction to Vaxigrip Tetra IM Injection 0.5 ml/pre-filled syringe

Inactivated influenza vaccine, also known as the flu shot, is an immunization given to people six months of age and older to protect them against infection from Influenza virus. It decreases the risk of developing serious complications caused by the virus, such as hospitalization, pneumonia, and even death. The vaccine is usually given once a year, during the fall season in the United States.

Uses for Vaxigrip Tetra IM Injection 0.5 ml/pre-filled syringe

Inactivated influenza vaccine is used to prevent infection caused by influenza virus. It is recommended to receive the vaccine at least 2 weeks before the start of the flu season and annually to maintain immunity.

Brand Name	Vaxigrip Tetra
Type	IM Injection
Weight	0.5 ml/pre-filled syringe
Generic	Inactivated Influenza Vaccine
Manufacturer	Synovia Pharma PLC.
Available in	English বাংলা

Mechanism of Action

Inactivated influenza vaccine works by stimulating the body's immune system to make antibodies that recognize and defend against the virus. These antibodies then protect people from infection when they are exposed to the virus, by attacking and killing the virus before it has an opportunity to take hold.

How Long Does It Take To Work?

It generally takes about two weeks for the vaccine to develop protective immunity, meaning it may take two weeks for the body to develop protection from the virus after receiving the vaccine.

Absorption

The inactivated influenza vaccine is injected subcutaneously (under the skin) or intramuscularly (into a muscle). Once injected, the vaccine is absorbed into the bloodstream, where it stimulates the body's immune system to produce antibodies that protect against infection.

Route of Elimination

The vaccine is not metabolized in the body, and it is excreted through the urine and feces.

Dosage

Dosage:

Adults and children over 36 months of age: 0.5ml
Children from 6 to 35 months of age: clinical data are limited. Doses of 0.25 ml or 0.5 ml have been used.

Administrations: For children who have not previously been vaccinated, a second dose should be given after an interval of at least 4 weeks. If half a dose (0.25 ml) is to be administered, discard half the contained volume (up to the mark indicated on the syringe barrel), before injection. Immunisation should be carried out by intramuscular or deep subcutaneous injection. The vaccine should be allowed to reach room temperature before use. Shake before use. Seroprotection is generally obtained within 2 to 3 weeks. The duration of postvaccinal immunity to homologous strains or to strains closely related to the vaccine strains varies but is usually 6-12 months.

The amount of vaccine that should be given to one person is determined by age and other factors, such as existing health conditions. The vaccine is available in single dose or multiple dose vials. Generally, a single 0.5 mL dose is recommended for adults and children.

Administration

The inactivated influenza vaccine is typically administered via an intramuscular injection. It should be injected into the muscle in the upper arm. It can also be administered subcutaneously in the arm.

Side Effects

Common side effects of the inactivated influenza vaccine include soreness, redness, and swelling at the injection site, headache, body aches, and low-grade fever. These side effects typically resolve within a few days.

Toxicity

The inactivated influenza vaccine is considered to be safe and the chance of serious side effects and toxicity is very low.

Precautions

People who are allergic to eggs, the ingredients of the vaccine, or who have had a severe allergic reaction to a previous dose of influenza vaccine should not receive the vaccine. People who have a fever should wait until the fever has gone away before receiving the vaccine.

Interactions

The inactivated influenza vaccine does not interact with other medications, herbs, supplements, or foods.

Disease Interaction

The inactivated influenza vaccine does not interact with any known diseases.

Drug Interactions

The inactivated influenza vaccine does not interact with any known drugs.

Food Interactions

The inactivated influenza vaccine does not interact with any known foods.

Pregnancy Use

The safety of the inactivated influenza vaccine during pregnancy has not been established. However, it is generally recommended that pregnant women receive the vaccine to protect them from influenza, as the disease can be more severe in pregnant women.

Lactation Use

The safety of the inactivated influenza vaccine during lactation has not been established. However, it is generally recommended that lactating women receive the vaccine to protect them from influenza.

Acute Overdose

There is no known risk associated with receiving more than the recommended dose of the vaccine. However, it is recommended to speak to a healthcare provider if more than the recommended dose has been received.

Contraindication

The inactivated influenza vaccine should not be given to people who are allergic to eggs, the ingredients of the vaccine, or who have had a severe allergic reaction to a previous dose of the vaccine.

Use Directions

The vaccine should be injected into the muscle in the upper arm. It can also be injected subcutaneously in the arm. Be sure to follow the directions on the package and to use a new needle and syringe for each injection.

Storage Conditions

The inactivated influenza vaccine should be stored in a refrigerator at 2°C to 8°C. Do not freeze the vaccine. Opened vials should be used within seven days and unused vials should be discarded according to the manufacturer’s instructions.