Uramed Cream

Urea Introduction

Urea, also known as carbamide, is an organic compound with the chemical formula (NH2)2CO. It is a white crystalline solid that is highly soluble in water and a widely used non-toxic and inexpensive source of nitrogen, especially in agriculture. Urea is an end product of the breakdown of proteins, and is produced in the liver from ammonia.

Uses for Urea

Urea is used in various applications including agriculture, pharmaceuticals, cosmetics, medical diagnostics, cleaning agents, research and food production. In agriculture, urea is used as a fertilizer to provide a source of nitrogen for plants as well as to promote the growth of beneficial microorganisms in the soil. It is also used in medical diagnostics to measure blood urea nitrogen (BUN) levels as an indicator of kidney function. In the food industry, urea is an ingredient in some types of food additives. Urea is also used in the synthesis of diuretics, steroids, drugs used to treat high cholesterol, and other pharmaceuticals.

Brand Name	Uramed
Type	Cream
Weight	10% w/w
Generic	Urea (10%)
Manufacturer	ZAS Corporation
Available in	English বাংলা

Mechanism of Action

Urea works by providing a source of nitrogen which can then be used by plants and microorganisms to increase their growth. The nitrogen present in urea can also be used to help convert other nutrients in the soil into more readily usable forms.

How Long Does It Take to Work?

Once applied to the soil, it typically takes several weeks for urea to begin to take effect. Depending on the type of soil and climate conditions, it may take up to several months for the full benefits of urea to be realized.

Absorption

Urea is readily absorbed into the soil, where it is converted into ammonium, nitrate, and carbon dioxide by microbial action. This process takes several weeks, but can be accelerated with the addition of a nitrogen-releasing fertilizer such as ammonium nitrate.

Route of Elimination

Urea is not eliminated from the body, and most of the urea ingested is excreted as ammonia in the urine. A small fraction of the urea is also lost in sweat.

Dosage

Urea 10% cream is applied topically. Wash affected areas well, rinse off all traces of soap, dry and apply sparingly twice daily. Occlusive dressings may be used, but are usually unnecessary because of the self-occlusive nature of the cream.

Use in children: Urea 10% cream can be used in all age groups.

Urea is generally applied to soil at a rate of 1-3% (by weight) depending on the type of soil and crop. It can be applied directly to the soil or in combination with other fertilizers such as ammonium nitrate, potassium nitrate, superphosphate, or other sources of nitrogen.

Administration

Urea is typically applied to the soil by either broadcasting or side-dressing. It can also be applied through irrigation or as part of a fertilizer solution.

Side Effects

Urea is a non-toxic compound and, when used correctly, poses no significant health risks. However, overuse of urea can lead to excessive nitrogen levels in the soil, leading to plant health issues such as reduced water uptake, drooping leaves and decreased crop yields. Additionally, overuse of urea can lead to increased levels of nitrates in the groundwater, which can lead to contamination of drinking water supplies.

Toxicity

Urea is not considered to be toxic, however large amounts of urea can irritate the skin or eyes. Ingestion of large amounts of urea can cause abdominal pain, vomiting, diarrhea, and other gastrointestinal symptoms.

Precautions

Urea should be used according to label instructions and all safety precautions should be observed. It should not be applied in areas with high traffic or in areas where standing water may accumulate. It should also be kept out of reach of children.

Interaction

Urea is not known to interact with any drugs, foods, or diseases.

Drug Interaction

Urea is not known to interact with any other drugs.

Food Interactions

Urea is not known to interact with any foods.

Pregnancy Use

Urea should not be used during pregnancy unless absolutely necessary and recommended by a doctor.

Lactation Use

Urea should not be used during lactation unless absolutely necessary and recommended by a doctor.

Acute Overdose

Urea has a low toxicity and acute overdose is unlikely. In case of ingestion, seek medical attention and follow the instructions of a healthcare professional.

Contraindication

Urea is not known to be contraindicated with any drugs, foods, or diseases.

Use Direction

Urea should be used according to label instructions. It is best applied when the soil temperature is between 18° and 24°C and should never be applied when soil temperatures are higher than 28°C as this can reduce the effectiveness of the urea. Urea should be mixed with the soil immediately after application.

Storage Condition

Urea should be stored in a cool, dry place and away from direct sunlight. Keep away from children and pets.

Volume of Distribution

Urea is quickly absorbed into the soil, where it is then converted to other forms of nitrogen compounds. Most of the urea is not available for uptake by plants, but is lost to the environment through leaching, volatilization, and denitrification.

Half Life

Urea has a short half-life and is rapidly degraded in the soil, typically within two to four weeks.

Clearance

Urea is quickly cleared from the soil, as it is absorbed and converted into other forms of nitrogen compounds. Most of the urea is not available for uptake by plants, but is lost to the environment through leaching, volatilization, and denitrification.

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