Name: Trusert HZ Tablet 40 mg+12.5 mg
Brand: Trusert HZ
SKU: trusert-hz-tablet-40-mg-12-5-mg
Price: 12 BDT
Availability: OnlineOnly

Brand Name

Trusert HZ

Type

Tablet

Weight

40 mg+12.5 mg

Generic

Telmisartan + Hydrochlorothiazide

Manufacturer

Ziska Pharmaceuticals Ltd.

Price

Unit: ৳ 12.00 (3 x 10: ৳ 360.00) Strip: ৳ 120.00

About Trusert HZ

Trusert HZ Tablet (Ziska Pharmaceuticals Ltd.) is a brand medicine containing the generic Telmisartan + Hydrochlorothiazide . Current listed price in Bangladesh: Unit: ৳ 12.00 (3 x 10: ৳ 360.00) Strip: ৳ 120.00.

Medical information for Trusert HZ Tablet 40 mg+12.5 mg

Uses, dosage, side effects, and safety details below apply to Trusert HZ Tablet 40 mg+12.5 mg (generic: Telmisartan + Hydrochlorothiazide). This is general information — consult a doctor before use.

Introduction

Trusert HZ Tablet 40 mg+12.5 mg is a combination drug containing telmisartan, a selective angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic. It is used to treat hypertension (high blood pressure).

Uses for

Trusert HZ Tablet 40 mg+12.5 mg is prescribed to treat hypertension (high blood pressure) in adults and adolescents (12 years and older). It may in some cases be used to treat heart failure or kidney failure related to hypertension. In addition, it may be used to reduce the risk of stroke or heart attack in patients at risk for these complications.

Mechanism of Action

Telmisartan works by blocking the action of angiotensin II, a hormone which narrows blood vessels and increases blood pressure. Hydrochlorothiazide, a thiazide diuretic, works by increasing the amount of salt and water removed from the body, helping to lower blood pressure.

How long does it take to work?

It can take several weeks of regular use for Trusert HZ Tablet 40 mg+12.5 mg to reach its full effect on blood pressure. However, some people may notice an improvement sooner, typically within 1–2 weeks.

Absorption

Once taken, Trusert HZ Tablet 40 mg+12.5 mg is quickly absorbed in the body, with peak concentration reached within 1-3 hours.

Route of Elimination

After being absorbed in the body, Trusert HZ Tablet 40 mg+12.5 mg is eliminated primarily through the kidneys.

Dosage

The recommended starting dose of Trusert HZ Tablet 40 mg+12.5 mg in adults and adolescents (12 years and older) with hypertension is 40 mg/12.5 mg once daily. Depending on blood pressure response, the dose may be increased to 80 mg once daily, if necessary. The maximum dose is 80 mg/25 mg per day.

Administration

Trusert HZ Tablet 40 mg+12.5 mg should be taken orally with or without food, once daily.

Side Effect

Common side effects of Trusert HZ Tablet 40 mg+12.5 mg includes dizziness, headache, stuffy or runny nose, nausea, abdominal pain, sore throat, cough, fatigue, impotence in men, and menstrual irregularities in women.

Toxicity

Trusert HZ Tablet 40 mg+12.5 mg has been found to be safe when taken as prescribed. On rare occasions, overdose of Trusert HZ Tablet 40 mg+12.5 mg can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Precaution

Trusert HZ Tablet 40 mg+12.5 mg must not be administered during pregnancy, since it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug. The drug should also be used cautiously in patients with liver disease, kidney disease, diabetes, and in elderly patients.

Interaction

Trusert HZ Tablet 40 mg+12.5 mg may interact with other drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Disease Interaction

Trusert HZ Tablet 40 mg+12.5 mg may worsen conditions associated with kidney failure, such as high potassium levels, low blood pressure, and lupus.

Drug Interaction

Drugs that can interact with Trusert HZ Tablet 40 mg+12.5 mg include nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Food Interactions

No food interactions have been reported with Trusert HZ Tablet 40 mg+12.5 mg.

Pregnancy Use

Trusert HZ Tablet 40 mg+12.5 mg must not be administered during pregnancy, as it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug.

Lactation Use

It is not known whether Trusert HZ Tablet 40 mg+12.5 mg passes into breast milk. It should be avoided while breastfeeding, as it may cause harm to the nursing infant.

Acute Overdose

Acute overdose of Trusert HZ Tablet 40 mg+12.5 mg can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Contraindication

Trusert HZ Tablet 40 mg+12.5 mg should not be used in patients with allergy or hypersensitivity to any of its components, or in patients with severe renal impairment.

Use direction

Trusert HZ Tablet 40 mg+12.5 mg should be taken orally with or without food, once daily.

Storage condition

Trusert HZ Tablet 40 mg+12.5 mg should be stored at room temperature (59–86°F/ 15–30°C).

Volume of Distribution

Trusert HZ Tablet 40 mg+12.5 mg is widely distributed throughout the body, with a volume of distribution of about 4.3 L/kg.

Half Life

The elimination half-life of Trusert HZ Tablet 40 mg+12.5 mg is about 11–14 hours.

Clearance

The total clearance of Trusert HZ Tablet 40 mg+12.5 mg is approximately 0.3 L/hr/kg.

Medical review

Last reviewed: 30 Aug 2024

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.