Temolina Tablet

Temolina Tablet 5 mg Introduction

Temolina Tablet 5 mg is an oral anti-diabetic drug for the treatment of type 2 diabetes that belongs to the dipeptidyl peptidase 4 (DPP-4) inhibitor class. It is used together with a proper diet and exercise program to control high blood sugar. It works by reducing the amount of sugar (glucose) produced by the liver. It also increases the body’s sensitivity to insulin, enabling it more effectively to lower blood sugar.

Uses

Temolina Tablet 5 mg is used to control high blood sugar levels in adults and children with type 2 diabetes. It is generally used in combination with proper diet and exercise program.

Brand Name	Temolina
Type	Tablet
Weight	5 mg
Generic	Linagliptin
Manufacturer	Team Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Temolina Tablet 5 mg blocks the enzyme dipeptidyl peptidase 4 (DPP-4) from breaking down the incretin hormones, which normally regulate glucose. By blocking DPP-4, Temolina Tablet 5 mg increases levels of active incretin hormones, which reduce blood glucose.

How Long Does it Take to Work?

It may take up to 2 weeks before you notice an improvement in your blood glucose levels. Consult your doctor to determine if a change in your dosage is required.

Absorption

Temolina Tablet 5 mg is slowly and completely absorbed from the gastrointestinal (GI) tract with peak plasma concentration achieved 0.5 to 1.5 hours after oral administration.

Route of Elimination

Temolina Tablet 5 mg is mainly eliminated through bile as unchanged drug.

Dosage

Linagliptin 5 mg once daily. If added to metformin, the dose of metformin should be maintained and linagliptin administered concomitantly. When used in combination with a sulfonylurea, a lower dose of the sulphonylurea may be considered to reduce the risk of hypoglycaemia.

Patients with renal impairment: No dose adjustment required. Linagliptin can be taken with or without a meal at any time of the day.

Temolina Tablet 5 mg is available in tablets of 5 mg and 10 mg. The recommended adult dosage for initial therapy is 5mg orally once daily. The recommended maintenance dosage is 10mg orally once daily. The dosage may be adjusted based on the response.

Administration

Temolina Tablet 5 mg should be taken with or without food. It should be taken at the same time, each day.

Side Effect

The most common side effects associated with linagliptin include: headache, nausea, upper respiratory infection, runny nose, sore throat, and abdominal pain. Other side effects include dizziness, muscle pain, and back pain.

Toxicity

Temolina Tablet 5 mg is generally considered safe and well-tolerated. There have been no reported cases of significant or acute toxicity.

Precautions

Patients should inform their doctor of any medical conditions, allergies, pregnancy, and breast-feeding before taking linagliptin. Patients with kidney disease or liver problems should use this medication with caution.

Interaction

Temolina Tablet 5 mg may interact with other medications, including oral antidiabetic drugs, stimulants, and other medications. Consult your doctor before taking linagliptin if you are taking any other medications.

Disease Interaction

Temolina Tablet 5 mg has not been studied in patients with significant hepatic or renal impairment. Therefore, caution should be used in these patients.

Drug Interactions

Temolina Tablet 5 mg may interact with other medications, including oral antidiabetic drugs, stimulants, and other medications.

Food Interactions

Temolina Tablet 5 mg is not affected by food and may be taken with or without food.

Pregnancy Use

Temolina Tablet 5 mg is a pregnancy category B drug and is suggested not to be used during pregnancy unless necessary and as determined by your doctor.

Lactation Use

Temolina Tablet 5 mg is excreted in human milk in small amounts. The potential risk of the infant should be considered before utilizing this drug.

Acute Overdose

In clinical studies, an overdose of 400mg of Temolina Tablet 5 mg resulted in no serious adverse reactions. Other smaller overdoses have resulted in similar results with no serious adverse reactions.

Contraindication

Temolina Tablet 5 mg is contraindicated in patients with a known sensitivity to the active ingredient or any of the excipients.

Use Direction

Take Temolina Tablet 5 mg exactly as prescribed by your doctor. Do not take more than the recommended dose and do not stop taking this medication abruptly unless your doctor advises you to do so.