Telmipres Plus Tablet

Introduction

Telmipres Plus Tablet 80 mg+25 mg is a combination drug containing telmisartan, a selective angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic. It is used to treat hypertension (high blood pressure).

Uses for

Telmipres Plus Tablet 80 mg+25 mg is prescribed to treat hypertension (high blood pressure) in adults and adolescents (12 years and older). It may in some cases be used to treat heart failure or kidney failure related to hypertension. In addition, it may be used to reduce the risk of stroke or heart attack in patients at risk for these complications.

Brand Name	Telmipres Plus
Type	Tablet
Weight	80 mg+25 mg
Generic	Telmisartan + Hydrochlorothiazide
Manufacturer	Incepta Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Telmisartan works by blocking the action of angiotensin II, a hormone which narrows blood vessels and increases blood pressure. Hydrochlorothiazide, a thiazide diuretic, works by increasing the amount of salt and water removed from the body, helping to lower blood pressure.

How long does it take to work?

It can take several weeks of regular use for Telmipres Plus Tablet 80 mg+25 mg to reach its full effect on blood pressure. However, some people may notice an improvement sooner, typically within 1–2 weeks.

Absorption

Once taken, Telmipres Plus Tablet 80 mg+25 mg is quickly absorbed in the body, with peak concentration reached within 1-3 hours.

Route of Elimination

After being absorbed in the body, Telmipres Plus Tablet 80 mg+25 mg is eliminated primarily through the kidneys.

Dosage

The recommended starting dose of Telmipres Plus Tablet 80 mg+25 mg in adults and adolescents (12 years and older) with hypertension is 40 mg/12.5 mg once daily. Depending on blood pressure response, the dose may be increased to 80 mg once daily, if necessary. The maximum dose is 80 mg/25 mg per day.

Administration

Telmipres Plus Tablet 80 mg+25 mg should be taken orally with or without food, once daily.

Side Effect

Common side effects of Telmipres Plus Tablet 80 mg+25 mg includes dizziness, headache, stuffy or runny nose, nausea, abdominal pain, sore throat, cough, fatigue, impotence in men, and menstrual irregularities in women.

Toxicity

Telmipres Plus Tablet 80 mg+25 mg has been found to be safe when taken as prescribed. On rare occasions, overdose of Telmipres Plus Tablet 80 mg+25 mg can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Precaution

Telmipres Plus Tablet 80 mg+25 mg must not be administered during pregnancy, since it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug. The drug should also be used cautiously in patients with liver disease, kidney disease, diabetes, and in elderly patients.

Interaction

Telmipres Plus Tablet 80 mg+25 mg may interact with other drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Disease Interaction

Telmipres Plus Tablet 80 mg+25 mg may worsen conditions associated with kidney failure, such as high potassium levels, low blood pressure, and lupus.

Drug Interaction

Drugs that can interact with Telmipres Plus Tablet 80 mg+25 mg include nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Food Interactions

No food interactions have been reported with Telmipres Plus Tablet 80 mg+25 mg.

Pregnancy Use

Telmipres Plus Tablet 80 mg+25 mg must not be administered during pregnancy, as it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug.

Lactation Use

It is not known whether Telmipres Plus Tablet 80 mg+25 mg passes into breast milk. It should be avoided while breastfeeding, as it may cause harm to the nursing infant.

Acute Overdose

Acute overdose of Telmipres Plus Tablet 80 mg+25 mg can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Contraindication

Telmipres Plus Tablet 80 mg+25 mg should not be used in patients with allergy or hypersensitivity to any of its components, or in patients with severe renal impairment.