Relexid Tablet

Relexid Tablet 200 mg

Relexid Tablet 200 mg is an oral antibiotic which belongs to the family of penicillin. It is used to treat urinary tract infections caused by susceptible organisms like Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, and Enterobacter species. Apart from that, it can also be used for treatment of gonorrhea, salmonella enteric fever, could be used along with other medicines to treat certain infections.

Uses for Relexid Tablet 200 mg

Relexid Tablet 200 mg is used to treat the following infections caused by susceptible organisms: Urinary tract infections caused by Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, Enterobacter species, Skin and soft tissue infections, Respiratory tract infections, Gonococcal urethritis, Salmonella enteric fever.

Brand Name	Relexid
Type	Tablet
Weight	200 mg
Generic	Pivmecillinam
Manufacturer	Renata Limited
Available in	English বাংলা

Mechanism of Action

Relexid Tablet 200 mg works by interfering with the growth of bacteria by disturbing the bacterial cell wall. It is bactericidal and works by disrupting the structure of the bacterial cell wall. This action results in the death of the bacterial cells.

How Long Does it Take to Work?

The effects of pivmecillinam start to appear within 3 to 4 days of treatment. However, it is best to complete the full course of treatment even if you start to feel better after taking the first dose.

Absorption

Relexid Tablet 200 mg is rapidly and almost completely absorbed in the gastrointestinal tract.

Route of Elimination

Relexid Tablet 200 mg is excreted primarily in the urine, with approximately 85% of an oral dose being recovered in the urine unchanged.

Dosage

Adults:

The usual dose: 1-2 tablets 3 times daily according to severity of the infection.
In acute uncomplicated cystitis: initially 400 mg then 200 mg every 8 hours for 3 days.
In chronic or recurrent bacteriurea: 400 mg 6-8 hours.
For the treatment of salmonellosis (including enteric fever): 1.2-2.4 gm daily for 14 days. To eliminate salmonella carriage, therapy may be prolonged for 2-4 weeks. In complicated urinary tract infection the usual treatment time is 1-2 weeks.
For prophylactic treatment of recurrent urinary tract infections: 1 tablet every evening is recommended.

Children:

Weighing less than 20 kg should be given 20-60 mg/kg divided into 3-4 daily doses. Those weighing more than 20 kg should receive normal adult dose.
In shigellosis: 20 mg/kg 4 times a day for 5 days.
For UTI: 20-40 mg/kg/day in 3-4 divided doses
For salmonellosis: 30-60 mg/kg/day in 3-4 divided doses

The usual dose of pivmecillinam is 400 mg taken orally, three times a day for 5 days. It should be taken with food to prevent stomach irritation and ensure complete absorption. Higher dosage may be used for severe infections.

Administration

Relexid Tablet 200 mg should be taken with food to prevent stomach irritation and ensure complete absorption. The capsule should be swallowed whole and not crushed or chewed.

Side Effects

Relexid Tablet 200 mg can cause some common side effects such as: nausea, vomiting, diarrhea, headache, rashes, dizziness, abdominal pain. Notify your doctor if any of these effects become severe.

Toxicity

The therapeutic index (or safety ratio) of pivmecillinam is low. In case of an overdose, seek medical attention immediately. Overdose can cause severe nausea, vomiting, and seizures.

Precautions

Before taking pivmecillinam, inform your doctor if you have any allergies or if you are taking any other medicines, such as antacids or vitamins. Also, the use of pivmecillinam should be avoided if you are pregnant or breastfeeding.

Interaction

Relexid Tablet 200 mg can interact with certain medications, such as antacids. It can also interact with certain vitamins and supplements. Inform your doctor about all medications, herbs, and supplements you are taking before taking pivmecillinam.

Disease Interaction

Relexid Tablet 200 mg should not be used if you have a history of renal impairment, hepatic impairment, or if you are allergic to penicillin. It can also interact with certain diseases, such as diabetes, so make sure to inform your doctor about any medical conditions you have before taking pivmecillinam.

Drug Interactions

Relexid Tablet 200 mg can interact with certain drugs, such as antacids. In addition, it can also interact with vitamins and supplements. Make sure to inform your doctor about all medications, herbs, and supplements you are taking before taking pivmecillinam.

Food Interactions

No specific food interactions with pivmecillinam have been seen. Make sure to take it with food to prevent stomach irritation and ensure complete absorption.

Pregnancy Use

Relexid Tablet 200 mg should be used with caution during pregnancy as it can cause harm to the unborn child. Seek medical advice before taking if you are pregnant or planning to become pregnant.

Lactation Use

Relexid Tablet 200 mg should be used with caution during lactation as it can be secreted in the breast milk. Seek medical advice before taking if you are breastfeeding.

Acute Overdose

In case of an overdose, seek medical attention immediately. Overdose can cause severe nausea, vomiting, and seizures.

Contraindication

Relexid Tablet 200 mg should not be used if you have a history of renal impairment, hepatic impairment, or if you are allergic to penicillin.

Use Direction

Take the capsule with food to prevent stomach irritation and ensure complete absorption. Swallow the whole capsule, do not crush or chew it. Do not take more than the recommended dose as it can be harmful and seek medical advice if you experience any unusual symptoms.