POP-D Tablet 0.075 mg Introduction

POP-D Tablet 0.075 mg is a progestin hormone that is used for contraception and is a derivative of the naturally occurring hormone progesterone. It is used in the manufacture of desogestrel as an active ingredient in combination with ethinylestradiol for use in oral contraceptive tablets.

POP-D Tablet 0.075 mg Uses

POP-D Tablet 0.075 mg is primarily used for contraception and is also used to treat heavy menstrual bleeding, endometriosis, and breast pain. It is also used in combination with other hormones to treat menopausal symptoms.

POP-D Tablet 0.075 mg Mechanism of Action

POP-D Tablet 0.075 mg works by suppressing ovulation and, in cases of endometriosis, focuses on reducing the concentrations of estrogen responsible for stimulating the growth of endometrial tissue.

How Long Does it Take for POP-D Tablet 0.075 mg to Work?

POP-D Tablet 0.075 mg typically works within 24-48 hours after administration and the effects can last up to three to six months.

POP-D Tablet 0.075 mg Absorption

POP-D Tablet 0.075 mg is rapidly absorbed from the gastrointestinal tract and has a bioavailability of approximately 50-80%. The peak plasma concentration of desogestrel is achieved after approximately four to five hours.

POP-D Tablet 0.075 mg Route of Elimination

POP-D Tablet 0.075 mg is excreted via the urine and feces as metabolites. Approximately 30% is excreted in the urine, while the remainder is excreted via the feces.

POP-D Tablet 0.075 mg Dosage

The recommended dosage of desogestrel varies based on the indication: for contraception use, the starting dose is 30 mcg once daily for 21 consecutive days followed by a 7-day rest period. For treatment of endometriosis, the recommended dose is 30 mcg twice a day for 21 consecutive days. For treatment of PMS symptoms, the recommended dose is 30 mcg once daily for 21 consecutive days.

POP-D Tablet 0.075 mg Administration

POP-D Tablet 0.075 mg can be taken with or without food. It is recommended to take it at the same time each day to maintain effectiveness.

POP-D Tablet 0.075 mg Side Effects

Common side effects of desogestrel include nausea, headache, breast tenderness, bloating, and breakthrough bleeding. If any of these side effects do not improve or are bothersome, it is recommended to speak to a doctor. Rare but serious side effects include an increased risk of blood clots, stroke, and heart attack.

POP-D Tablet 0.075 mg Toxicity

There is no established threshold for desogestrel toxicity. However, if large doses are taken, the symptoms may be similar to those of an overdose of other steroid hormones, such as dizziness, headache, nausea, vomiting, and sluggishness.

POP-D Tablet 0.075 mg Precautions

POP-D Tablet 0.075 mg should be used with caution in women with a history of cardiovascular disease, diabetes, hypertension, liver disease, or thromboembolic disorders. Women should also not take the medication if they are pregnant or breastfeeding.

POP-D Tablet 0.075 mg Interactions

POP-D Tablet 0.075 mg interacts with certain drugs, such as anticonvulsants, protease inhibitors, certain antibiotics, antifungals, and St. John's wort. It is important to tell a doctor about any other medications being taken before starting desogestrel.

POP-D Tablet 0.075 mg Disease Interaction

POP-D Tablet 0.075 mg may interact with certain diseases, such as liver disease, cardiovascular disease, diabetes, hypertension, or thromboembolic disorders. It is important to inform a doctor of any pre-existing health conditions before starting desogestrel.

POP-D Tablet 0.075 mg Drug Interactions

POP-D Tablet 0.075 mg may interact with certain drugs and affect their metabolism or activity. These drugs include anticonvulsants, protease inhibitors, certain antibiotics, antifungals, and St. John's wort.

POP-D Tablet 0.075 mg Food Interactions

There are no known food interactions with desogestrel.

POP-D Tablet 0.075 mg Use in Pregnancy

POP-D Tablet 0.075 mg should not be used during pregnancy as it may cause harm to a developing fetus. Women are advised to avoid becoming pregnant while taking desogestrel.

POP-D Tablet 0.075 mg Use in Lactation

POP-D Tablet 0.075 mg should not be used during lactation as it can be passed to an infant through the breastmilk and may cause adverse effects in a nursing infant.

POP-D Tablet 0.075 mg Acute Overdose

If an overdose of desogestrel is suspected, seek medical attention immediately. If taken orally, the symptoms may be similar to other steroid hormones, such as dizziness, headache, nausea, vomiting, and sluggishness.

POP-D Tablet 0.075 mg Contraindication

POP-D Tablet 0.075 mg is contraindicated in women with a history of thromboembolic disorders, breast cancer, or other hormone-sensitive cancer.

POP-D Tablet 0.075 mg Use Directions

POP-D Tablet 0.075 mg should be taken as directed by a doctor. Do not increase or decrease the dose without medical advice. Follow the directions on the package insert and take the medication as prescribed.

POP-D Tablet 0.075 mg Storage Conditions

POP-D Tablet 0.075 mg should be stored at room temperature and away from light and moisture. Keep the medication out of the reach of children.

POP-D Tablet 0.075 mg Volume of Distribution

The volume of distribution for desogestrel is approximately 3.7 L/kg.

POP-D Tablet 0.075 mg Half Life

The half-life of desogestrel is approximately 17-24 hours.

POP-D Tablet 0.075 mg Clearance

The average clearance of desogestrel is approximately 6 L/hr/kg.

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*** Taking medicines without doctor's advice can cause long-term problems.
Dr. Nazma Ahmed

Dr. Nazma Ahmed

Skin, Allergy & Sexual Diseases Specialist

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Dr. Md. Nurul Akther Chowdhury

Dr. Md. Nurul Akther Chowdhury

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