Nystat Tablet

Nystat Tablet 500000 unit Introduction

Nystat Tablet 500000 unit is a polyene antifungal medication used to treat superficial fungal infections of the skin, nails, and mouth. It is typically administered topically through a cream, ointment, powder, or suspension, as long as it is not taken by mouth, and it has been approved by the U.S. Food and Drug Administration (FDA).

Matain Uses

Nystat Tablet 500000 unit is used to treat various superficial or cutaneous fungal infections in humans caused by fungi, such as Candida albicans, Pityrosporum ovale, and Trichophyton species. It is sometimes used to prevent and treat fungal infections in the kidney, penis, vagina, and urinary tract. It is also used off-label to treat oral thrush (oral candidiasis).

Brand Name	Nystat
Type	Tablet
Weight	500000 unit
Generic	Nystatin
Manufacturer	ACME Laboratories Ltd.
Available in	English বাংলা

Mechanism of Action

Nystat Tablet 500000 unit works by inhibiting the formation of sterols needed for cell wall production in fungi. As the cell wall is destroyed, the fungi is unable to grow or reproduce, thereby halting its progression and reverting to its natural state as a dormant organism.

How Long Does it Take to Work?

Nystat Tablet 500000 unit is a rapid-acting antifungal medication; it is typically effective within 3-5 days of usage, although the effectiveness of the medication may vary based on the severity of the infection.

Absorption

Nystat Tablet 500000 unit has low systemic absorption (less than 0.4%) when used topically and is rapidly cleared from the blood. The peak serum concentration of the drug is achieved within 4-24 hours after topical administration.

Route of Elimination

Nystat Tablet 500000 unit is primarily eliminated in the feces, with up to 95% of the drug being excreted in the bile within 48 hours of administration. The remainder of the drug is excreted in the urine.

Dosage

For topical use, the recommended dose of nystatin is 100,000 to 200,000 international units per gram of the cream or ointment applied twice daily for 14 days. For oral or intravesical use, the recommended dose of nystatin is 10,000 to 100,000 international units per day, divided and taken 3-4 times daily.

Administration

Nystat Tablet 500000 unit is typically administered topically through a cream, ointment, powder, or suspension, as long as it is not taken by mouth. Oral or intravesical nystatin should be taken with meals or immediately after meals to maximize the absorption of the drug.

Side Effects

The most common side effects of topical nystatin are burning, stinging, irritation, and itching at the site of application. Other possible side effects include headache, dizziness, and nausea.

Toxicity

Nystat Tablet 500000 unit is generally considered safe and non-toxic. If irritation or other symptoms persist, contact a healthcare professional until proper medical advice can be acquired.

Precautions

Nystat Tablet 500000 unit should not be used for more than 14 consecutive days and should not be used in the eyes without consulting with a healthcare professional. Patients should not wear contact lenses while using nystatin.

Interaction

Nystat Tablet 500000 unit has no known clinically significant pharmacokinetic interactions with other medications.

Disease Interaction

Nystat Tablet 500000 unit is not recommended for patients with kidney or liver dysfunction, as it may worsen the condition.

Drug Interactions

Nystat Tablet 500000 unit has no known clinically significant pharmacokinetic interactions with other medications.

Food Interactions

Nystat Tablet 500000 unit is not known to interact with foods.

Pregnancy Use

Nystat Tablet 500000 unit is generally regarded as safe for use during pregnancy, although caution should be taken if it is used in large doses.

Lactation Use

Nystat Tablet 500000 unit is likely to be safe for use during breastfeeding, although caution should be taken if it is used in large doses.

Acute Overdose

An acute overdose of nystatin is unlikely, as the drug is rapidly cleared from the body. No specific antidote is available.

Contraindication

Nystat Tablet 500000 unit is contraindicated in patients who are hypersensitive to it or any of its components.

Use Direction

Nystat Tablet 500000 unit should be applied topically to affected areas, paying particular attention to avoid contact with the eyes or mouth. Oral or intravesical nystatin should be taken by following instructions provided by a healthcare professional and should not be taken without consulting a professional.