Nandrolone Phenylpropionate

Introduction

Nandrolone Phenylpropionate (NPP) is an anabolic steroid used in medicine and bodybuilding. It is a derivative of testosterone and is used primarily to promote muscle growth and improve bone density. It is known for its shorter ester compared to other nandrolone derivatives, which results in a faster onset and shorter duration of action.

Uses

Nandrolone Phenylpropionate is used for:

Treating anemia and osteoporosis by promoting red blood cell production and bone health.
Supporting muscle mass and strength in patients with chronic wasting diseases or severe weight loss.
As part of hormone replacement therapy to manage testosterone deficiency in men.

Brand Name	Nandrolone Phenylpropionate
Type
Weight
Generic	Nandrolone Phenylpropionate
Manufacturer
Available in	English বাংলা

Mechanism of Action

Nandrolone Phenylpropionate works by binding to androgen receptors in muscle and bone tissues. This binding promotes protein synthesis and increases muscle mass and bone density. It also stimulates erythropoiesis (red blood cell production) by enhancing erythropoietin levels in the kidneys.

How Long Does It Take to Work?

The effects of Nandrolone Phenylpropionate can be observed within a few weeks of starting treatment. Muscle growth and increased bone density typically become noticeable after about 4 to 6 weeks. For medical conditions such as anemia, improvements in red blood cell count may also be seen within a similar time frame.

Absorption

Nandrolone Phenylpropionate is administered intramuscularly. After injection, it is gradually absorbed into the bloodstream. The rate of absorption can be influenced by the injection site and formulation.

Route of Elimination

Nandrolone Phenylpropionate is metabolized primarily in the liver. It is excreted mainly through urine as metabolites. The half-life of the drug influences how long it remains active in the body and impacts the frequency of administration.

Dosage

As an adjunct to specific therapies and dietary measures in pathologic conditions characterized by a negative nitrogen balance: Recommended dose is 25-50 mg every week.

For the palliative treatment of selected cases of disseminated mammary carcinoma in women: Recommended dose is 50 mg every week.

Osteoporosis: Recommended dose is 50 mg every week.

For an optimal therapeutic effect, it is necessary to administer adequate amounts of vitamins, minerals and protein in a calorie-rich diet. Nandrolone Phenylpropionate should be administered by deep intramuscular injection.

The dosage of Nandrolone Phenylpropionate varies based on the condition being treated:

For anemia and osteoporosis: 50 to 100 mg administered intramuscularly every 1 to 4 weeks.
For muscle wasting and strength improvement: 50 to 100 mg every 1 to 2 weeks, depending on patient response and tolerance.

Dosage adjustments are made based on individual patient needs, response, and side effects.

Administration

Nandrolone Phenylpropionate is administered intramuscularly, typically into the gluteal or deltoid muscles. It should be injected according to the prescribed schedule and technique to ensure proper absorption and minimize side effects.

Side Effects

Common side effects include:

Acne.
Hair loss.
Increased aggression or mood swings.
Fluid retention and edema.

Serious side effects may include:

Hepatic damage or liver dysfunction.
Cardiovascular issues such as hypertension and changes in cholesterol levels.
Hormonal imbalances, including gynecomastia (breast tissue development in men).

Toxicity

Overdosing on Nandrolone Phenylpropionate can lead to severe side effects such as liver damage, cardiovascular problems, and hormonal imbalances. Treatment for overdose typically involves supportive care, including monitoring and managing symptoms, and discontinuation of the drug.

Precautions

Precautions include:

Monitoring liver function regularly during treatment.
Assessing cardiovascular health and cholesterol levels.
Using with caution in patients with a history of prostate or breast cancer.

Interaction

Nandrolone Phenylpropionate may interact with:

Anticoagulants: May enhance their effects, increasing the risk of bleeding.
Other anabolic steroids: May increase the risk of side effects and adverse reactions.

Disease Interaction

Use with caution in patients with:

Hepatic impairment or liver disease, as it can exacerbate liver issues.
Cardiovascular conditions, including hypertension and heart disease.

Drug Interaction

Drug interactions include:

CYP3A4 inhibitors or inducers: May affect the metabolism of Nandrolone Phenylpropionate .
Drugs affecting liver function: May alter the drug's metabolism and effectiveness.

Food Interactions

Food interactions are minimal. However, a balanced diet supporting overall health can help manage side effects and support the efficacy of the drug.

Pregnancy Use

Nandrolone Phenylpropionate is not recommended during pregnancy due to potential risks to fetal development and possible masculinization of the female fetus. Consult a healthcare provider before use if pregnant or planning to become pregnant.

Lactation Use

The use of Nandrolone Phenylpropionate during lactation is not well studied. It is generally advised to avoid its use while breastfeeding due to potential risks to the infant. Consult a healthcare provider for alternatives if necessary.

Acute Overdose

In the event of an acute overdose, symptoms may include severe hormonal imbalances and liver dysfunction. Treatment involves supportive care, monitoring, and symptomatic management. Discontinuation of the drug and addressing complications are essential.

Contraindication

Contraindications include:

Hypersensitivity to Nandrolone or any of its components.
Active liver disease or severe hepatic impairment.
Pregnancy and lactation.

Use Direction

Follow the prescribed dosage and administration instructions carefully. Inject Nandrolone Phenylpropionate intramuscularly as directed. Do not exceed the recommended dose and schedule to avoid adverse effects.

Storage Conditions

Store Nandrolone Phenylpropionate at room temperature, away from light and moisture. Keep it out of reach of children. Follow any specific storage instructions provided by the manufacturer.

Volume of Distribution

The volume of distribution for Nandrolone Phenylpropionate is approximately 1.3 L/kg, indicating its extensive distribution into body tissues.

Half Life

The elimination half-life of Nandrolone Phenylpropionate is approximately 4.5 days. This relatively short half-life necessitates more frequent dosing compared to other nandrolone esters.

Clearance

Nandrolone Phenylpropionate is primarily cleared through hepatic metabolism. Its clearance rate can be affected by liver function and concurrent use of other medications.

See in details version Nandrolone Phenylpropionate also Nandrolone Phenylpropionate in bangla