Moxifloxacin Hydrochloride (Ophthalmic)
Moxifloxacin Hydrochloride (Ophthalmic) is an antibiotic used to treat eye infections caused by bacteria such as pink eye (conjunctivitis), keratitis (inflammation of the cornea), and blepharitis (inflammation of eyelash follicles). It works by stopping the growth of the bacteria that cause the infections.
Uses
Moxifloxacin Hydrochloride (Ophthalmic) is used to treat bacterial eye infections. It is used in adults and children of all ages.
Mechanism of Action
Moxifloxacin Hydrochloride (Ophthalmic) works by stopping the growth of the bacteria that cause the eye infections. It is a fluoroquinolone antibiotic.
How Long Does It Take To Work?
Moxifloxacin Hydrochloride (Ophthalmic) usually begins to work within 24 hours of application and symptoms typically start to improve within 48 hours. It should be taken as recommended by your doctor.
Absorption, Route of Elimination, Dosage, Administration
Moxifloxacin Hydrochloride (Ophthalmic) is available in 0.5% w/v solution. The solution should be applied to the affected eye(s) twice daily for 7 days. It is absorbed through the eye and can be eliminated via the renal system. It is not recommended for intravitreal (injected into the eyeball) or oral use and should not be ingested.
Side Effect
Common side effects of Moxifloxacin Hydrochloride (Ophthalmic) include temporary blurred vision, burning, stinging, and itching at the application site.
Toxicity
Moxifloxacin Hydrochloride (Ophthalmic) is generally considered safe when used correctly. It is not toxic at therapeutic concentrations.
Precautions
Moxifloxacin Hydrochloride (Ophthalmic) should not be used if you are allergic to it or any of its ingredients. It should also not be used if you have a corneal infection, if your eyesight has deteriorated recently, if you have any eye inflammation or irritation, or if you are pregnant or nursing. Talk to your doctor before using this medication.
Interaction
Moxifloxacin Hydrochloride (Ophthalmic) should not be used with other ophthalmic medications. It may interact with other medications, such as topical or systemic (taken by mouth) antibiotics, antifungals, or steroids. Talk to your doctor before using any other medications with Moxifloxacin Hydrochloride (Ophthalmic).
Disease Interaction
Moxifloxacin Hydrochloride (Ophthalmic) should not be used in patients with known hypersensitivity to quinolones. It should also not be used in patients with corneal infection and intraocular inflammation or irritation.
Drug Interaction
Moxifloxacin Hydrochloride (Ophthalmic) may interact with certain medications, such as other ophthalmic medications, topical antibiotics, antifungals, or steroids. Talk to your doctor before combining with other medications.
Food Interactions
Moxifloxacin Hydrochloride (Ophthalmic) is not known to interact with food or beverages.
Pregnancy Use
Moxifloxacin Hydrochloride (Ophthalmic) should not be used if you are pregnant or planning to become pregnant. Speak to your doctor for more information.
Lactation Use
Moxifloxacin Hydrochloride (Ophthalmic) should not be used if you are breastfeeding. Speak to your doctor for more information.
Acute Overdose
In case of an acute overdose, seek immediate medical attention. Symptoms may include blurred vision, stinging, burning, and itching at the application site.
Contraindication
Moxifloxacin Hydrochloride (Ophthalmic) is contraindicated in patients with known hypersensitivity to quinolones or any of its ingredients, in patients with corneal infection, and in patients with intraocular inflammation or irritation.
Use Direction
Moxifloxacin Hydrochloride (Ophthalmic) should be applied to the affected eye(s) twice daily for 7 days. It should not be used for a longer period of time than recommended by your doctor. Do not apply more than two drops in a single application or more than four drops per day.
Storage Condition
Moxifloxacin Hydrochloride (Ophthalmic) should be stored at room temperature (3–8 °C). Do not store the solution in the refrigerator and keep it away from heat and moisture.
Volume of Distribution
Moxifloxacin Hydrochloride (Ophthalmic) has a volume of distribution of approximately 5.4 L/kg.
Half Life
Moxifloxacin Hydrochloride (Ophthalmic) has a terminal half-life of approximately 11.2 hours.
Clearance
Moxifloxacin Hydrochloride (Ophthalmic) is primarily eliminated by the kidneys and has a renal clearance of approximately 19 ml/min.
