Introduction
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Uses
Flurazine Tablet 1 mg is a phenothiazine used to treat depression, anxiety, and agitation.
For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
Associated Conditions
Pharmacodynamics
Flurazine Tablet 1 mg is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Flurazine Tablet 1 mg has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Mechanism of Action
Flurazine Tablet 1 mg blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Half Life
10-20 hours
Toxicity
Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
Food Interactions
- Avoid excessive or chronic alcohol consumption. Ingesting alcohol may potentiate the sedative and CNS depressant effects of trifluoperazine.
