Introduction
Evening primrose oil (EPO) is derived from the seeds of a plant Oenothera biennis. The oil from the plant is extracted and contains gamma-linoleic acid (GLA) an essential fatty acid that can not be produced by the body and must be obtained through diet or supplementation. This oil is available in capsules or liquid forms as a dietary supplement.
Uses for
Evening primrose oil is used for a variety of health conditions including skin disorders, PMS, menopause, eczema, psoriasis, headaches, rheumatoid arthritis, diabetes, multiple sclerosis, nerve damage, and high cholesterol. It is sometimes applied to the skin for treating skin diseases.
| Brand Name | Evening primrose oil |
|---|---|
| Type | |
| Weight | |
| Generic | Evening primrose oil |
| Manufacturer | |
| Available in | English বাংলা |
Mechanism of Action
The mechanism of action of Evening Primrose is believed to be due to an alteration of omega-6 fatty acid metabolism. It is known to enhance the conversion of linoleic acid to gamma-linoleic acid (GLA). GLA is thought to be involved in the production of hormones and other metabolites which many be involved in the management of various conditions.
How long does it take to work?
The amount of time it takes to notice the effects of evening primrose varies between individuals. Most people will notice a noticeable improvement within two to four weeks, although it may take longer for some people.
Absorption
Although Evening Primrose Oil is not highly absorbed, it is well-absorbed by the stomach and intestinal tract. A lipase, pancreatic enzyme, is known to help with the absorption of Evening Primrose Oil.
Route of Elimination
After its absorption, Evening Primrose Oil is metabolized in the liver and excreted in the form of fatty acids in the urine.
Dosage
Atopic & Allergic Dermatitis:- Adult dosage: 1 capsule 2 times daily.
- Children dosage: 1 capsule 1/2 times daily.
Premenstrual Syndrome (PMS): 1 Capsule 2 times daily at morning & night with or after meal.
Rheumatoid arthritis: 1 Capsule daily Or as directed by the registered physician.
For general health, adults can take 500-2,000 mg of Evening Primrose Oil daily in divided doses or taken as a single dose. For skin conditions, 1,000 mg to 3,000 mg of Evening Primrose Oil is taken daily in divided doses. For PMS, 800 mg to 1,600 mg in divided doses is taken every day. For rheumatoid arthritis, 1,200 mg of Evening Primrose Oil is taken daily. For diabetes, 1,500 mg to 3,000 mg of Evening Primrose Oil is taken daily. For multiple sclerosis, 2,000 mg of Evening Primrose Oil is taken daily.
Administration
For adults, Evening Primrose Oil is best taken with a meal at mealtime. It can also be taken with food or without food. If taken without food, it should be taken with a full glass of water. It is available in tablets, liquid, and capsule forms.
Side Effects
Evening Primrose Oil is well-tolerated and has few side effects when taken in recommended dosages. Common side effects include stomach upset, nausea, and headache. It may also cause drowsiness and dizziness.
Toxicity
Evening Primrose Oil is not known to be toxic when taken in recommended dosages. It is suggested that individuals consult a doctor before taking it.
Precautions
It is suggested that individuals consult a doctor prior to taking Evening Primrose Oil as it may interact with other medications. Women who are pregnant or breast-feeding should talk to their doctor before taking Evening Primrose Oil.
Interactions
EPO may interact with certain medications, including anticoagulants, diuretics, antihypertensives, and anticonvulsants. It may also interact with herbs and supplements, including garlic, ginkgo biloba, and St. John's wort. People taking medication should talk to their doctor before taking EPO.
Disease Interactions
EPO is not recommended for people who have bleeding disorders, diabetes, high blood pressure, seizures, or allergies. It is also not recommended for people who are pregnant or nursing.
Drug Interactions
EPO may interact with a number of medications, including anticoagulants, diuretics, antihypertensives, and anticonvulsants. People taking medication should talk to their doctor before taking EPO.
Food Interactions
There are no known food interactions with EPO. However, it is important to take EPO with food to ensure adequate absorption.
Pregnancy Use
EPO should not be used during pregnancy as it may have adverse effects on the fetus. Women who are pregnant or planning to become pregnant should talk to their doctor before taking EPO.
Lactation Use
Due to lack of sufficient studies, EPO should be avoided in breastfeeding women. Women who are breastfeeding should talk to their doctor before taking EPO.
Acute Overdose
The symptoms of an acute overdose of EPO are not known. However, it is unlikely that an overdose would be serious and the individual should seek medical attention if they experience any severe symptoms.
Contraindications
EPO is contraindicated in people with bleeding disorders, diabetes, high blood pressure, seizures, allergies, and people who are pregnant or breastfeeding.
Use Directions
EPO should be taken as directed by a doctor or pharmacist. It is typically taken with meals to ensure absorption. It should not be taken with alcohol or other medicines that may interact with it. It can be taken in capsule, tablet, or liquid forms.
Storage Condition
EPO should be stored at room temperature, in its original container, and away from direct sunlight, heat, and moisture.
Volume of Distribution
The volume of distribution of EPO is not known.
Half Life
The half-life of EPO is not known.
Clearance
The clearance of EPO is not known.
See in details version Evening primrose oil also Evening primrose oil in bangla
Some Frequently Asked Questions About Evening primrose oil
Dr. Nargish Khanam
Gynecology, Obstetrics, Infertility Specialist & Laparoscopic Surgeon
