Esita Tablet

Introduction

Esita Tablet 5 mg is a selective serotonin reuptake inhibitor (SSRI) medication used to treat depression and anxiety disorders. It is also used off-label for treatment of other disorders like fibromyalgia and migraine. It works by increasing the amount of serotonin in the brain, which helps to regulate mood and improve mood stability.

Uses

Esita Tablet 5 mg is used to treat major depressive disorder and generalized anxiety disorder. It may also be used to treat other conditions as prescribed by the doctor.

Brand Name	Esita
Type	Tablet
Weight	5 mg
Generic	Escitalopram Oxalate
Manufacturer	Healthcare Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Esita Tablet 5 mg works by selectively inhibiting serotonin reuptake transporter, resulting in prolonged serotonin activity in the brain. It increases serotonin levels, which helps regulate and improve mood.

How long does it take to work?

It can take up to two weeks for the full effect of Esita Tablet 5 mg to take effect.

Absorption

Esita Tablet 5 mg is rapidly and completely absorbed after oral administration, with peak concentrations occurring within 1-2 hours.

Route of Elimination

Esita Tablet 5 mg is mainly eliminated in the urine via renal excretion.

Dosage

Safety of daily doses above 20 mg has not been demonstrated. Escitalopram Oxalate is administered as a single daily dose and may be taken with or without food.

Major depressive episodes: Usual dosage is 10 mg once daily. Depending on individual patient response, the dose may be increased to a maximum of 20 mg daily. Usually, 2-4 weeks are necessary to obtain an antidepressant response. After the symptoms resolve, treatment for at least 6 months is required for consolidation of the response.

Panic disorder with or without agoraphobia: An initial dose of 5 mg is recommended for the first week before increasing the dose to 10 mg daily. The dose may be further increased, up to a maximum of 20 mg daily, dependent on individual patient response. Maximum effectiveness is reached after about 3 months. The treatment lasts several months.

Social anxiety disorder: Usual dosage is 10 mg once daily. Usually, 2-4 weeks are necessary to obtain symptom relief. The dose may subsequently, depending on individual patient response, be decreased to 5 mg or increased to a maximum of 20 mg daily. Social anxiety disorder is a disease with a chronic course, and treatment for 12 weeks is recommended to consolidate response. Long-term treatment of responders has been studied for 6 months and can be considered on an individual basis to prevent relapse; treatment benefits should be re-evaluated at regular intervals. Social anxiety disorder is a well-defined diagnostic terminology of a specific disorder, which should not be confounded with excessive shyness. Pharmacotherapy is only indicated if the disorder interferes significantly with professional and social activities. The place of this treatment compared to cognitive behavioural therapy has not been assessed. Pharmacotherapy is part of an overall therapeutic strategy.

Generalised anxiety disorder: Initial dosage is 10 mg once daily. Depending on the individual patient response, the dose may be increased to a maximum of 20 mg daily. Long term treatment of responders has been studied for at least 6 months in patients receiving 20 mg/day. Treatment benefits and dose should be re-evaluated at regular intervals.

Obsessive-Compulsive Disorder: Initial dosage is 10 mg once daily. Depending on the individual patient response, the dose may be increased to a maximum of 20 mg daily. As OCD is a chronic disease, patients should be treated for a sufficient period to ensure that they are symptom-free. Treatment benefits and dose should be re-evaluated at regular intervals. The recommended dose for adults is 10 mg to 20 mg daily. Lower doses may be prescribed for elderly patients or people with kidney problems. The maximum recommended dosage is 20 mg.

Administration

Esita Tablet 5 mg is generally taken orally once daily in the morning or evening, with or without food.

Side Effects

Some common side effects include nausea, headaches, dizziness, sleepiness, dry mouth, insomnia, and decreased appetite. More serious side effects are increased risk of suicide, increased bleeding, and serotonin syndrome.

Toxicity

Esita Tablet 5 mg has not been associated with toxicity in therapeutic doses. Toxicity can occur with very high doses, leading to agitation, confusion, and seizures.

Precautions

Esita Tablet 5 mg should be used with caution in patients with bipolar disorder, seizure disorder, or glaucoma. It should also be used with caution in pregnant or nursing women, and in children.

Interaction

Esita Tablet 5 mg may interact with other medications, including MAO inhibitors, antipsychotics, and anti-seizure medications. It may also interact with certain foods or drinks such as alcohol and caffeine.

Disease Interactions

Esita Tablet 5 mg can interact with certain diseases like bipolar disorder and seizure disorders as mentioned before, and can also interact with diseases like bleeding disorders, heart diseases, and liver diseases.

Drug Interactions

Esita Tablet 5 mg may interact with other medications, like MAO inhibitors, antipsychotics, and anti-seizure medications.

Food Interactions

Esita Tablet 5 mg can interact with certain foods or drinks such as alcohol and caffeine.

Pregnancy Use

Esita Tablet 5 mg should not be used during pregnancy as it can increase the risk of birth defects.

Lactation Use

Esita Tablet 5 mg should be used with caution in breastfeeding women as the drug can be secreted in breast milk.

Acute Overdose

Signs of an overdose may include drowsiness, confusion, seizures and coma.

Contraindications

Esita Tablet 5 mg should not be used in patients with a known hypersensitivity to Esita Tablet 5 mg.

Use Direction

Esita Tablet 5 mg should be taken as directed by the prescriber. Generally, it is taken once a day, in the morning or evening, with or without food.

Storage Condition

Esita Tablet 5 mg should be stored at room temperature, away from moisture and light.

Volume of Distribution

The volume of distribution of escitalopram is 12.1 ± 10.6 L/kg.

Half-life

The half-life of escitalopram is 27 to 32 hours.

Clearance

The hepatic clearance of escitalopram is 0.2 L/hr/kg.

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Some Frequently Asked Questions About Esita Tablet 5 mg

1. What is Esita Tablet 5 mg?

Esita Tablet 5 mg is an antidepressant in the selective serotonin reuptake inhibitor (SSRI) class, primarily used to treat depression and anxiety disorders by increasing serotonin levels in the brain.

2. How does Esita Tablet 5 mg work?

Esita Tablet 5 mg works by inhibiting the reuptake of serotonin in the brain, thereby increasing its levels and improving mood and anxiety symptoms.

3. What conditions is Esita Tablet 5 mg used to treat?

It is used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, panic disorder, and obsessive-compulsive disorder (OCD).

4. How should I take Esita Tablet 5 mg?

Esita Tablet 5 mg is usually taken once daily, with or without food. It is available in tablet and liquid form. Follow your doctor’s instructions for the proper dosage.

5. What is the recommended dosage for Esita Tablet 5 mg?

The typical starting dose is 10 mg per day, which may be increased to 20 mg per day after a week, depending on your response and tolerance.

6. Can I take Esita Tablet 5 mg with food?

Yes, Esita Tablet 5 mg can be taken with or without food. It does not affect its efficacy.

7. What should I do if I miss a dose of Esita Tablet 5 mg?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose—do not double the dose to make up for a missed one.

8. How long does it take for Esita Tablet 5 mg to start working?

It can take several weeks (typically 2-4 weeks) to start noticing the full benefits of Esita Tablet 5 mg, although some people may feel improvement in symptoms earlier.

9. What are the common side effects of Esita Tablet 5 mg?

Common side effects may include:

Nausea
Headache
Insomnia
Sexual dysfunction
Dry mouth

10. What are the serious side effects of Esita Tablet 5 mg?

Serious side effects include:

Suicidal thoughts or behaviors (particularly in young adults)
Serotonin syndrome (symptoms include agitation, hallucination, fever, and seizures)
Severe allergic reactions (rash, difficulty breathing, swelling of the face or throat)
Low sodium levels (symptoms include headache, confusion, and weakness)

11. Can Esita Tablet 5 mg cause weight gain?

Some people may experience weight gain, but it is not a common side effect. Maintaining a healthy diet and exercise routine can help mitigate this risk.

12. Can Esita Tablet 5 mg cause drowsiness?

Yes, drowsiness or fatigue can occur, particularly when first starting the medication. Avoid driving or operating heavy machinery if you feel drowsy.

13. Can I drink alcohol while taking Esita Tablet 5 mg?

It is advisable to avoid alcohol while taking Esita Tablet 5 mg, as alcohol can increase the risk of side effects such as drowsiness, dizziness, and impaired judgment.

14. Can Esita Tablet 5 mg be used in children?

Esita Tablet 5 mg can be prescribed to children 12 years and older for depression, but its use in younger children is not recommended due to concerns over safety and efficacy.

15. Can I stop taking Esita Tablet 5 mg suddenly?

No, stopping abruptly can lead to withdrawal symptoms such as irritability, dizziness, nausea, and sensory disturbances. It’s important to taper off under the supervision of a doctor.

16. How long should I take Esita Tablet 5 mg?

The duration of treatment varies. Some individuals may take it for several months or longer, while others may only need it for a shorter period. Always follow your doctor’s guidance regarding treatment duration.

17. Can Esita Tablet 5 mg be used during pregnancy?

Esita Tablet 5 mg should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor for guidance.

18. Can I take Esita Tablet 5 mg while breastfeeding?

Esita Tablet 5 mg is excreted in breast milk, and while it is considered relatively safe, discuss the risks and benefits with your healthcare provider before using it during breastfeeding.

19. How should Esita Tablet 5 mg be stored?

Store Esita Tablet 5 mg at room temperature, away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children.

20. What happens if I overdose on Esita Tablet 5 mg?

An overdose can lead to symptoms such as drowsiness, nausea, vomiting, fast heart rate, and serotonin syndrome. Seek immediate medical attention if an overdose is suspected.

21. Can I take Esita Tablet 5 mg with other antidepressants?

Taking Esita Tablet 5 mg with other antidepressants should only be done under the supervision of a doctor, as combining SSRIs with other antidepressants can increase the risk of serotonin syndrome.

22. Can I take Esita Tablet 5 mg with other medications?

Esita Tablet 5 mg may interact with various medications, including certain painkillers, blood thinners, and other antidepressants. Always inform your doctor about all medications you are taking.

23. Can Esita Tablet 5 mg cause sexual problems?

Yes, sexual side effects such as decreased libido, delayed orgasm, or erectile dysfunction can occur in some individuals.

24. How should I handle missed doses of Esita Tablet 5 mg?

If you miss a dose, take it as soon as you remember unless it’s close to the time for your next dose. Never double up to make up for a missed dose.

25. Can Esita Tablet 5 mg cause suicidal thoughts?

Escitalopram, like other antidepressants, can increase the risk of suicidal thoughts or behaviors, especially in young adults. It is essential to monitor for changes in mood or behavior.

26. Is Esita Tablet 5 mg effective for anxiety?

Yes, Esita Tablet 5 mg is commonly prescribed to treat generalized anxiety disorder (GAD) and social anxiety disorder, as it helps to reduce excessive worry and nervousness.

27. Is Esita Tablet 5 mg effective for depression?

Yes, Esita Tablet 5 mg is effective in treating major depressive disorder by balancing serotonin levels in the brain, which improves mood and emotional well-being.

28. Can I switch from another antidepressant to Esita Tablet 5 mg?

Switching from one antidepressant to another should always be done under the supervision of a healthcare provider to minimize withdrawal symptoms and potential interactions.

29. Can Esita Tablet 5 mg cause dizziness?

Dizziness can occur, particularly when standing up quickly. It’s important to rise slowly from sitting or lying positions to avoid feeling lightheaded.

30. Can I use Esita Tablet 5 mg with a painkiller?

Escitalopram can be used with some painkillers, but caution is necessary when combining it with non-steroidal anti-inflammatory drugs (NSAIDs) or blood thinners, as this may increase the risk of bleeding.

31. Can Esita Tablet 5 mg cause dry mouth?

Dry mouth is a common side effect. Drinking water or using sugar-free gum can help alleviate this symptom.

32. What should I do if I experience severe side effects from Esita Tablet 5 mg?

If you experience severe side effects such as difficulty breathing, swelling, or persistent dizziness, contact your healthcare provider immediately or seek emergency medical attention.

33. Can Esita Tablet 5 mg cause nausea?

Nausea is a common side effect, especially when starting the medication. Taking it with food or at bedtime may help reduce this symptom.

34. Can Esita Tablet 5 mg cause headaches?

Headaches can occur, particularly when starting treatment. If headaches persist, consult your doctor for advice on managing them.

35. Can Esita Tablet 5 mg be used for insomnia?

Although Esita Tablet 5 mg can help with anxiety and depression, it is not typically prescribed for insomnia. However, improvements in mood and anxiety may indirectly improve sleep.

36. How does Esita Tablet 5 mg affect serotonin levels?

Esita Tablet 5 mg increases serotonin levels in the brain by blocking its reuptake, which helps regulate mood, anxiety, and overall emotional well-being.

37. Is Esita Tablet 5 mg safe for long-term use?

Esita Tablet 5 mg is generally considered safe for long-term use under the supervision of a doctor, but regular check-ups are recommended to monitor for side effects.

38. Can I take Esita Tablet 5 mg if I have a history of substance abuse?

Esita Tablet 5 mg should be used with caution in individuals with a history of substance abuse, as it may have addictive properties in some cases. Consult with your doctor before starting treatment.

39. Can Esita Tablet 5 mg be used in combination with other anxiety medications?

Esita Tablet 5 mg can be combined with other anxiety medications under the guidance of a healthcare provider. Combining drugs can help improve treatment effectiveness but should be done with caution.

40. Can Esita Tablet 5 mg cause increased sweating?

Increased sweating is a rare side effect of Esita Tablet 5 mg. If this becomes bothersome, consult your healthcare provider.

41. Can I take Esita Tablet 5 mg if I have a heart condition?

If you have a heart condition, consult your doctor before taking Esita Tablet 5 mg. It may need to be adjusted or avoided in some cases.

42. Can Esita Tablet 5 mg cause trembling?

Tremors can occasionally occur, especially during the first few weeks of treatment. If tremors persist, inform your doctor.

43. Can Esita Tablet 5 mg be taken with other psychiatric medications?

Esita Tablet 5 mg can be taken with other psychiatric medications, but careful monitoring by a healthcare provider is necessary to avoid interactions.

44. Can Esita Tablet 5 mg cause sleep disturbances?

While Esita Tablet 5 mg can improve sleep by treating underlying anxiety and depression, some people may experience sleep disturbances such as insomnia or vivid dreams.

45. How should I stop taking Esita Tablet 5 mg?

Do not stop taking Esita Tablet 5 mg suddenly. Taper off gradually under your doctor’s guidance to avoid withdrawal symptoms.

46. Can Esita Tablet 5 mg interact with herbal supplements?

Yes, herbal supplements like St. John’s Wort can interact with Esita Tablet 5 mg, increasing the risk of serotonin syndrome. Consult your doctor before using any supplements.