Introduction
Escitalopram Oxalate is a selective serotonin reuptake inhibitor (SSRI) medication used to treat depression and anxiety disorders. It is also used off-label for treatment of other disorders like fibromyalgia and migraine. It works by increasing the amount of serotonin in the brain, which helps to regulate mood and improve mood stability.Uses
Escitalopram Oxalate is used to treat major depressive disorder and generalized anxiety disorder. It may also be used to treat other conditions as prescribed by the doctor.| Brand Name | Escitalopram Oxalate |
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| Type | |
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| Generic | Escitalopram Oxalate |
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| Available in | English বাংলা |
Mechanism of Action
Escitalopram Oxalate works by selectively inhibiting serotonin reuptake transporter, resulting in prolonged serotonin activity in the brain. It increases serotonin levels, which helps regulate and improve mood.How long does it take to work?
It can take up to two weeks for the full effect of Escitalopram Oxalate to take effect.Absorption
Escitalopram Oxalate is rapidly and completely absorbed after oral administration, with peak concentrations occurring within 1-2 hours.Route of Elimination
Escitalopram Oxalate is mainly eliminated in the urine via renal excretion.Dosage
Safety of daily doses above 20 mg has not been demonstrated. Escitalopram Oxalate is administered as a single daily dose and may be taken with or without food.Major depressive episodes: Usual dosage is 10 mg once daily. Depending on individual patient response, the dose may be increased to a maximum of 20 mg daily. Usually, 2-4 weeks are necessary to obtain an antidepressant response. After the symptoms resolve, treatment for at least 6 months is required for consolidation of the response.
Panic disorder with or without agoraphobia: An initial dose of 5 mg is recommended for the first week before increasing the dose to 10 mg daily. The dose may be further increased, up to a maximum of 20 mg daily, dependent on individual patient response. Maximum effectiveness is reached after about 3 months. The treatment lasts several months.
Social anxiety disorder: Usual dosage is 10 mg once daily. Usually, 2-4 weeks are necessary to obtain symptom relief. The dose may subsequently, depending on individual patient response, be decreased to 5 mg or increased to a maximum of 20 mg daily. Social anxiety disorder is a disease with a chronic course, and treatment for 12 weeks is recommended to consolidate response. Long-term treatment of responders has been studied for 6 months and can be considered on an individual basis to prevent relapse; treatment benefits should be re-evaluated at regular intervals. Social anxiety disorder is a well-defined diagnostic terminology of a specific disorder, which should not be confounded with excessive shyness. Pharmacotherapy is only indicated if the disorder interferes significantly with professional and social activities. The place of this treatment compared to cognitive behavioural therapy has not been assessed. Pharmacotherapy is part of an overall therapeutic strategy.
Generalised anxiety disorder: Initial dosage is 10 mg once daily. Depending on the individual patient response, the dose may be increased to a maximum of 20 mg daily. Long term treatment of responders has been studied for at least 6 months in patients receiving 20 mg/day. Treatment benefits and dose should be re-evaluated at regular intervals.
Obsessive-Compulsive Disorder: Initial dosage is 10 mg once daily. Depending on the individual patient response, the dose may be increased to a maximum of 20 mg daily. As OCD is a chronic disease, patients should be treated for a sufficient period to ensure that they are symptom-free. Treatment benefits and dose should be re-evaluated at regular intervals. The recommended dose for adults is 10 mg to 20 mg daily. Lower doses may be prescribed for elderly patients or people with kidney problems. The maximum recommended dosage is 20 mg.
Administration
Escitalopram Oxalate is generally taken orally once daily in the morning or evening, with or without food.Side Effects
Some common side effects include nausea, headaches, dizziness, sleepiness, dry mouth, insomnia, and decreased appetite. More serious side effects are increased risk of suicide, increased bleeding, and serotonin syndrome.Toxicity
Escitalopram Oxalate has not been associated with toxicity in therapeutic doses. Toxicity can occur with very high doses, leading to agitation, confusion, and seizures.Precautions
Escitalopram Oxalate should be used with caution in patients with bipolar disorder, seizure disorder, or glaucoma. It should also be used with caution in pregnant or nursing women, and in children.Interaction
Escitalopram Oxalate may interact with other medications, including MAO inhibitors, antipsychotics, and anti-seizure medications. It may also interact with certain foods or drinks such as alcohol and caffeine.Disease Interactions
Escitalopram Oxalate can interact with certain diseases like bipolar disorder and seizure disorders as mentioned before, and can also interact with diseases like bleeding disorders, heart diseases, and liver diseases.Drug Interactions
Escitalopram Oxalate may interact with other medications, like MAO inhibitors, antipsychotics, and anti-seizure medications.Food Interactions
Escitalopram Oxalate can interact with certain foods or drinks such as alcohol and caffeine.Pregnancy Use
Escitalopram Oxalate should not be used during pregnancy as it can increase the risk of birth defects.Lactation Use
Escitalopram Oxalate should be used with caution in breastfeeding women as the drug can be secreted in breast milk.Acute Overdose
Signs of an overdose may include drowsiness, confusion, seizures and coma.Contraindications
Escitalopram Oxalate should not be used in patients with a known hypersensitivity to Escitalopram Oxalate .Use Direction
Escitalopram Oxalate should be taken as directed by the prescriber. Generally, it is taken once a day, in the morning or evening, with or without food.Storage Condition
Escitalopram Oxalate should be stored at room temperature, away from moisture and light.Volume of Distribution
The volume of distribution of escitalopram is 12.1 ± 10.6 L/kg.Half-life
The half-life of escitalopram is 27 to 32 hours.Clearance
The hepatic clearance of escitalopram is 0.2 L/hr/kg.See in details version Escitalopram Oxalate also Escitalopram Oxalate in bangla
Some Frequently Asked Questions About Escitalopram Oxalate
1. What is Escitalopram Oxalate ?
Escitalopram Oxalate is an antidepressant in the selective serotonin reuptake inhibitor (SSRI) class, primarily used to treat depression and anxiety disorders by increasing serotonin levels in the brain.
2. How does Escitalopram Oxalate work?
Escitalopram Oxalate works by inhibiting the reuptake of serotonin in the brain, thereby increasing its levels and improving mood and anxiety symptoms.
3. What conditions is Escitalopram Oxalate used to treat?
It is used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, panic disorder, and obsessive-compulsive disorder (OCD).
4. How should I take Escitalopram Oxalate ?
Escitalopram Oxalate is usually taken once daily, with or without food. It is available in tablet and liquid form. Follow your doctor’s instructions for the proper dosage.
5. What is the recommended dosage for Escitalopram Oxalate ?
The typical starting dose is 10 mg per day, which may be increased to 20 mg per day after a week, depending on your response and tolerance.
6. Can I take Escitalopram Oxalate with food?
Yes, Escitalopram Oxalate can be taken with or without food. It does not affect its efficacy.
7. What should I do if I miss a dose of Escitalopram Oxalate ?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose—do not double the dose to make up for a missed one.
8. How long does it take for Escitalopram Oxalate to start working?
It can take several weeks (typically 2-4 weeks) to start noticing the full benefits of Escitalopram Oxalate , although some people may feel improvement in symptoms earlier.
9. What are the common side effects of Escitalopram Oxalate ?
Common side effects may include:
- Nausea
- Headache
- Insomnia
- Sexual dysfunction
- Dry mouth
10. What are the serious side effects of Escitalopram Oxalate ?
Serious side effects include:
- Suicidal thoughts or behaviors (particularly in young adults)
- Serotonin syndrome (symptoms include agitation, hallucination, fever, and seizures)
- Severe allergic reactions (rash, difficulty breathing, swelling of the face or throat)
- Low sodium levels (symptoms include headache, confusion, and weakness)
11. Can Escitalopram Oxalate cause weight gain?
Some people may experience weight gain, but it is not a common side effect. Maintaining a healthy diet and exercise routine can help mitigate this risk.
12. Can Escitalopram Oxalate cause drowsiness?
Yes, drowsiness or fatigue can occur, particularly when first starting the medication. Avoid driving or operating heavy machinery if you feel drowsy.
13. Can I drink alcohol while taking Escitalopram Oxalate ?
It is advisable to avoid alcohol while taking Escitalopram Oxalate , as alcohol can increase the risk of side effects such as drowsiness, dizziness, and impaired judgment.
14. Can Escitalopram Oxalate be used in children?
Escitalopram Oxalate can be prescribed to children 12 years and older for depression, but its use in younger children is not recommended due to concerns over safety and efficacy.
15. Can I stop taking Escitalopram Oxalate suddenly?
No, stopping abruptly can lead to withdrawal symptoms such as irritability, dizziness, nausea, and sensory disturbances. It’s important to taper off under the supervision of a doctor.
16. How long should I take Escitalopram Oxalate ?
The duration of treatment varies. Some individuals may take it for several months or longer, while others may only need it for a shorter period. Always follow your doctor’s guidance regarding treatment duration.
17. Can Escitalopram Oxalate be used during pregnancy?
Escitalopram Oxalate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor for guidance.
18. Can I take Escitalopram Oxalate while breastfeeding?
Escitalopram Oxalate is excreted in breast milk, and while it is considered relatively safe, discuss the risks and benefits with your healthcare provider before using it during breastfeeding.
19. How should Escitalopram Oxalate be stored?
Store Escitalopram Oxalate at room temperature, away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children.
20. What happens if I overdose on Escitalopram Oxalate ?
An overdose can lead to symptoms such as drowsiness, nausea, vomiting, fast heart rate, and serotonin syndrome. Seek immediate medical attention if an overdose is suspected.
21. Can I take Escitalopram Oxalate with other antidepressants?
Taking Escitalopram Oxalate with other antidepressants should only be done under the supervision of a doctor, as combining SSRIs with other antidepressants can increase the risk of serotonin syndrome.
22. Can I take Escitalopram Oxalate with other medications?
Escitalopram Oxalate may interact with various medications, including certain painkillers, blood thinners, and other antidepressants. Always inform your doctor about all medications you are taking.
23. Can Escitalopram Oxalate cause sexual problems?
Yes, sexual side effects such as decreased libido, delayed orgasm, or erectile dysfunction can occur in some individuals.
24. How should I handle missed doses of Escitalopram Oxalate ?
If you miss a dose, take it as soon as you remember unless it’s close to the time for your next dose. Never double up to make up for a missed dose.
25. Can Escitalopram Oxalate cause suicidal thoughts?
Escitalopram, like other antidepressants, can increase the risk of suicidal thoughts or behaviors, especially in young adults. It is essential to monitor for changes in mood or behavior.
26. Is Escitalopram Oxalate effective for anxiety?
Yes, Escitalopram Oxalate is commonly prescribed to treat generalized anxiety disorder (GAD) and social anxiety disorder, as it helps to reduce excessive worry and nervousness.
27. Is Escitalopram Oxalate effective for depression?
Yes, Escitalopram Oxalate is effective in treating major depressive disorder by balancing serotonin levels in the brain, which improves mood and emotional well-being.
28. Can I switch from another antidepressant to Escitalopram Oxalate ?
Switching from one antidepressant to another should always be done under the supervision of a healthcare provider to minimize withdrawal symptoms and potential interactions.
29. Can Escitalopram Oxalate cause dizziness?
Dizziness can occur, particularly when standing up quickly. It’s important to rise slowly from sitting or lying positions to avoid feeling lightheaded.
30. Can I use Escitalopram Oxalate with a painkiller?
Escitalopram can be used with some painkillers, but caution is necessary when combining it with non-steroidal anti-inflammatory drugs (NSAIDs) or blood thinners, as this may increase the risk of bleeding.
31. Can Escitalopram Oxalate cause dry mouth?
Dry mouth is a common side effect. Drinking water or using sugar-free gum can help alleviate this symptom.
32. What should I do if I experience severe side effects from Escitalopram Oxalate ?
If you experience severe side effects such as difficulty breathing, swelling, or persistent dizziness, contact your healthcare provider immediately or seek emergency medical attention.
33. Can Escitalopram Oxalate cause nausea?
Nausea is a common side effect, especially when starting the medication. Taking it with food or at bedtime may help reduce this symptom.
34. Can Escitalopram Oxalate cause headaches?
Headaches can occur, particularly when starting treatment. If headaches persist, consult your doctor for advice on managing them.
35. Can Escitalopram Oxalate be used for insomnia?
Although Escitalopram Oxalate can help with anxiety and depression, it is not typically prescribed for insomnia. However, improvements in mood and anxiety may indirectly improve sleep.
36. How does Escitalopram Oxalate affect serotonin levels?
Escitalopram Oxalate increases serotonin levels in the brain by blocking its reuptake, which helps regulate mood, anxiety, and overall emotional well-being.
37. Is Escitalopram Oxalate safe for long-term use?
Escitalopram Oxalate is generally considered safe for long-term use under the supervision of a doctor, but regular check-ups are recommended to monitor for side effects.
38. Can I take Escitalopram Oxalate if I have a history of substance abuse?
Escitalopram Oxalate should be used with caution in individuals with a history of substance abuse, as it may have addictive properties in some cases. Consult with your doctor before starting treatment.
39. Can Escitalopram Oxalate be used in combination with other anxiety medications?
Escitalopram Oxalate can be combined with other anxiety medications under the guidance of a healthcare provider. Combining drugs can help improve treatment effectiveness but should be done with caution.
40. Can Escitalopram Oxalate cause increased sweating?
Increased sweating is a rare side effect of Escitalopram Oxalate . If this becomes bothersome, consult your healthcare provider.
41. Can I take Escitalopram Oxalate if I have a heart condition?
If you have a heart condition, consult your doctor before taking Escitalopram Oxalate . It may need to be adjusted or avoided in some cases.
42. Can Escitalopram Oxalate cause trembling?
Tremors can occasionally occur, especially during the first few weeks of treatment. If tremors persist, inform your doctor.
43. Can Escitalopram Oxalate be taken with other psychiatric medications?
Escitalopram Oxalate can be taken with other psychiatric medications, but careful monitoring by a healthcare provider is necessary to avoid interactions.
44. Can Escitalopram Oxalate cause sleep disturbances?
While Escitalopram Oxalate can improve sleep by treating underlying anxiety and depression, some people may experience sleep disturbances such as insomnia or vivid dreams.
45. How should I stop taking Escitalopram Oxalate ?
Do not stop taking Escitalopram Oxalate suddenly. Taper off gradually under your doctor’s guidance to avoid withdrawal symptoms.
46. Can Escitalopram Oxalate interact with herbal supplements?
Yes, herbal supplements like St. John’s Wort can interact with Escitalopram Oxalate , increasing the risk of serotonin syndrome. Consult your doctor before using any supplements.
47. Does Escitalopram Oxalate affect appetite?
Some individuals may experience a change in appetite, either an increase or decrease. This can vary depending on the person.
48. What should I do if Escitalopram Oxalate doesn’t seem to be working?
If Escitalopram Oxalate does not seem to be effective, consult your doctor. They may adjust the dose or consider other treatment options.
49. Can Escitalopram Oxalate cause diarrhea?
Yes, diarrhea is a common side effect, particularly when starting the medication. If it persists, consult your healthcare provider.
50. Can Escitalopram Oxalate be used for panic attacks?
Yes, Escitalopram Oxalate is effective in treating panic disorder by reducing the frequency and severity of panic attacks.
