Coxpain Tablet

Coxpain Tablet 90 mg Introduction

Coxpain Tablet 90 mg is a nonsteroidal anti-inflammatory (NSAID) drug used for the treatment of symptoms of osteoarthritis and rheumatoid arthritis. It works by reducing hormones that cause inflammation and pain in the body. This drug belongs to a class of drugs known as Cox-2 inhibitors. It can also reduce inflammation in other parts of the body, such as in the eyes and skin.

Coxpain Tablet 90 mg Uses

Coxpain Tablet 90 mg is primarily used to reduce pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It may also be used to reduce the risk of colorectal polyps in patients with familial adenomatous polyposis.

Brand Name	Coxpain
Type	Tablet
Weight	90 mg
Generic	Etoricoxib
Manufacturer	Novo Healthcare and Pharma Ltd.
Available in	English বাংলা

Mechanism of Action

Coxpain Tablet 90 mg works by targeting the enzyme cyclooxygenase 2 (COX-2). This enzyme is responsible for the synthesis of prostaglandins, which are responsible for the pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. By targeting this enzyme, etoricoxib is able to reduce the pain and inflammation associated with these conditions.

How Long Does it Take to Work?

Coxpain Tablet 90 mg typically begins to work within 1 to 3 hours of taking the drug. The full effects of etoricoxib may take up to 2 weeks to be fully realized.

Absorption

Coxpain Tablet 90 mg is rapidly absorbed into the bloodstream after it is taken orally. Absorption is further increased with the presence of food, but it can be taken without food or with a meal. The maximum concentration of the drug is achieved after 1.5 to 2 hours.

Route of Elimination

Coxpain Tablet 90 mg is mainly eliminated via faeces, but a small amount is also eliminated via urine.

Dosage

Adult and adolescent over 16 years:

Osteoarthritis: The recommended dose is 30 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 60 mg once daily may increase efficacy.
Rheumatoid arthritis: The recommended dose is 90 mg once daily.
Ankylosing spondylitis: The recommended dose is 90 mg once daily.
Acute gouty arthritis: The recommended dose is 120 mg once daily. In clinical trials for acute gouty arthritis, Etoricoxib was given for 8 days.
Postoperative dental surgery pain: The recommended dose is 90 mg once daily, limited to a maximum of 3 days.

Some patients may require additional postoperative analgesia. As the cardiovascular risks of Etoricoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically, especially in patients with osteoarthritis. The recommended dosage of etoricoxib is 90 mg once daily. This dosage can be increased to 90 mg twice daily if necessary. It is important to consult your doctor before adjusting the dosage.

Administration

Coxpain Tablet 90 mg should be taken with or without food once or twice daily as directed by your doctor. Take the drug at the same time each day.

Side Effects

Common side effects of etoricoxib include nausea, diarrhea, dizziness, headache, constipation, gas, and stomach pain. Other less common side effects include rash, drowsiness, itchy eyes, and chest pain.

Toxicity

It is important to take etoricoxib as prescribed by your doctor and not exceed the recommended dose. Overdosing on etoricoxib can lead to serious side effects such as increased blood pressure, irregular heartbeat, kidney damage, and liver problems.

Precautions

Before taking etoricoxib, tell your doctor if you have any of the following conditions: hypertension, diabetes, congestive heart failure, a history of stroke or heart attack, kidney disease, liver disease, or asthma. Also tell your doctor if you are pregnant or breastfeeding.

Interaction

Coxpain Tablet 90 mg may interact with other medications, such as blood thinners and some antibiotics. It is important to inform your doctor of all medications you are taking before taking etoricoxib.

Disease Interaction

Coxpain Tablet 90 mg may interact with certain diseases, such as heart disease, kidney disease, and diabetes. It is important to inform your doctor of any pre-existing medical conditions before taking etoricoxib.

Drug Interaction

Coxpain Tablet 90 mg may interact with other drugs, including aspirin, warfarin, celecoxib, and ibuprofen. It is important to inform your doctor of all medications you are taking before taking etoricoxib.

Food Interactions

Coxpain Tablet 90 mg should be taken with or without food. Taking the drug with food may increase the absorption of the drug. It is important to speak to your doctor or pharmacist before taking the drug with food.

Pregnancy Use

Coxpain Tablet 90 mg should not be used during pregnancy. This drug can cause harm to an unborn baby, so it is important to inform your doctor if you are pregnant or planning to become pregnant while taking the drug.

Lactation Use

It is not known if etoricoxib passes into breast milk. Therefore, it is not recommended to take etoricoxib while breastfeeding.

Acute Overdose

An overdose of etoricoxib can cause serious health problems such as dizziness, confusion, drowsiness, low blood pressure, and kidney failure. If you suspect an overdose, seek immediate medical attention.

Contraindications

Coxpain Tablet 90 mg should not be used in patients with a known allergy to the drug or any of its ingredients. It should also not be used in patients who have had a previous hypersensitivity reaction to any other NSAID.

Use Direction

Coxpain Tablet 90 mg should be used as prescribed by your doctor. Do not exceed the recommended dosage. Take the drug with or without food as directed by your doctor.

Storage Conditions

Coxpain Tablet 90 mg should be stored at room temperature, away from direct light and moisture. Keep the drug in a tightly closed, childproof container.