Introduction
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Uses
Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.
Associated Conditions
Dosage
Oral:
- Immediate treatment of stroke due to a clot (ischemic stroke): 500-2000 mg of Citicoline per day, start within 24 hours of stroke.
- For decline in thinking skills due to stroke: 1000-2000 mg of Citicoline per day.
- Chronic cerebrovascular disease: 1000 mg daily in divided dose with or between meals for ongoing disease of the blood vessels that serve the brain.
- 1 to 2 injections daily.
- Adjust dosage according to the severity.
- Can be administered through intramuscular (IM), or intravenous (IV) [ 3 to 5 minutes] route.
