Clobeon Cream

Introduction

Clobetasol Propionate, Neomycin Sulphate, and Nystatin is a medication combination used for treating fungal and bacterial skin infections. It is also prescribed to reduce swelling, redness, and itching caused by certain skin conditions.

Uses for

This medication is used to treat fungal and bacterial infections of the skin. It can also help reduce swelling, redness, and itching from certain skin conditions.

Brand Name	Clobeon
Type	Cream
Weight	(0.5 mg+5 mg+1 Lac IU)/gm
Generic	Clobetasol Propionate + Neomycin Sulphate + Nystatin
Manufacturer	Julphar Bangladesh Ltd.
Available in	English বাংলা

Mechanism of Action

Clobetasol Propionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressant properties. Neomycin Sulphate is an aminoglycoside antibiotic that kills bacteria by inhibiting bacterial protein synthesis. Nystatin kills fungi by interfering with the synthesis of fungal cell membrane.

How Long Does it Take to Work

The length of time it takes for the medication to start working depends on the specific infection being treated and the severity of the infection. Generally, it can take from one to two weeks to experience significant improvement.

Absorption

Clobetasol Propionate, Neomycin Sulphate, and Nystatin is usually applied to the skin, and absorption of the drug into the bloodstream is usually low.

Route of Elimination

Clobetasol Propionate, Neomycin Sulphate, and Nystatin are generally excreted through the urine or feces.

Dosage

Adults: Apply sparingly to the affected area once or twice daily until improvement occurs. In very resistant lesion, especially where there is hyperkeratosis, the anti-inflammatory effect of this preparation can be enhanced (if necessary) by occluding the treatment area with polythene. Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed.

Elderly: This preparation is suitable for use in elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of Neomycin Sulphate may occur.

Children: This preparation is suitable for use in children (2 years and over) at the same dose as adults. A possibility of increased absorption exists in very young children, thus this cream/ointment is not recommended for use in neonates and infants (younger than 2 years). Clobetasol Propionate, Neomycin Sulphate, and Nystatin is typically applied to the affected skin area(s) one to three times daily. The dosage may be adjusted according to the severity of the infection and the response to therapy.

Administration

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should be applied to the affected area as instructed by the healthcare provider. The medication should be applied sparingly to the affected area and should not be allowed to come in contact with the eyes, nose, mouth, or irritated skin. After the medication is applied to the affected area, it should be gently massaged for even coverage.

Side Effects

The most common side effects of Clobetasol Propionate, Neomycin Sulphate, and Nystatin include burning, stinging, itching, redness, and skin dryness. In some cases, the skin may become irritated or inflamed, and in extreme cases the skin may blister or crack.

Toxicity

Clobetasol Propionate, Neomycin Sulphate, and Nystatin can be toxic if swallowed, and may cause severe skin reactions with prolonged use.

Precaution

Patients should inform their healthcare provider before using this medication if they have any allergies, a history of skin infections, or any other medical conditions. Patients should also not use the medication on broken skin or any areas where there is a rash, wound, or infection.

Interactions

Clobetasol Propionate, Neomycin Sulphate, and Nystatin may interact with other drugs, including antifungal medications, antibiotics, and antiviral medications. Patients should inform their healthcare providers of any other medications they are taking before using this medication.

Disease Interactions

Patients with certain medical conditions such as liver or kidney disease, diabetes, or a weakened immune system should inform their healthcare providers before using Clobetasol Propionate, Neomycin Sulphate, and Nystatin.

Drug Interactions

Clobetasol Propionate, Neomycin Sulphate, and Nystatin may interact with other drugs, and patients should inform their healthcare providers of any other medications they are taking before using this medication.

Food Interactions

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should not be taken with food, as it may decrease the effectiveness of the medication.

Pregnancy Use

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should be used during pregnancy only if the potential benefits outweigh the potential risks. Women should consult their healthcare providers before using this medication.

Lactation Use

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should not be used while breastfeeding as it may pass into the breastmilk and cause harm to the infant. Women should consult their healthcare providers before using this medication.

Acute Overdose

An acute overdose of Clobetasol Propionate, Neomycin Sulphate, and Nystatin can cause serious side effects. Patients should seek medical attention immediately if they experience any signs or symptoms of an overdose.

Contraindication

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should not be used by patients with a known hypersensitivity to any of the ingredients in the medication or those with a skin infection involving all layers of the skin.

Use Direction

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should be used as directed by a healthcare provider. If irritation or worsening of the condition occurs, patients should contact their healthcare provider immediately.

Storage Condition

Clobetasol Propionate, Neomycin Sulphate, and Nystatin should be stored in a cool, dry place away from direct light and heat.

Volume of Distribution

Clobetasol Propionate, Neomycin Sulphate, and Nystatin has a volume of distribution of 0.3 L/kg.

Half Life

The half life of Clobetasol Propionate, Neomycin Sulphate, and Nystatin is 4-11 hours.

Clearance

The clearance rate of Clobetasol Propionate, Neomycin Sulphate, and Nystatin is 10-80 mL/minute/1.73 m2.

See in details version Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm also Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm in bangla

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Some Frequently Asked Questions About Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm

1. What is Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is a combination medication used to treat various skin conditions. Clobetasol Propionate is a potent corticosteroid that reduces inflammation, Neomycin Sulphate is an antibiotic that prevents bacterial infections, and Nystatin is an antifungal that targets fungal infections.

2. What conditions can be treated with Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

This combination medication is used to treat inflammatory skin conditions that involve both bacterial and fungal infections, such as:

• Dermatitis
• Psoriasis
• Eczema
• Fungal skin infections complicated by bacterial infection

3. How does Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm work?

Clobetasol Propionate works by reducing inflammation and immune responses in the skin. Neomycin Sulphate prevents bacterial growth by inhibiting protein synthesis in bacteria. Nystatin works by binding to fungal cell membranes, causing them to become permeable, leading to fungal cell death.

4. How should Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be applied?

Apply a thin layer of the cream or ointment to the affected area once or twice daily, or as directed by your doctor. Avoid applying it to the face, groin, or underarms unless instructed. Do not apply it to open wounds or broken skin.

5. What are the common side effects of Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Common side effects include:

• Skin irritation or redness
• Burning or stinging sensation at the application site
• Itching
• Skin thinning (with prolonged use)
• Stretch marks
• Acne or folliculitis

If side effects persist or worsen, contact your healthcare provider.

6. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used on the face?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should not be used on the face unless specifically prescribed by a doctor. Prolonged use on the face can lead to skin thinning, irritation, and other side effects.

7. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used during pregnancy?

This combination medication should only be used during pregnancy if the benefits outweigh the potential risks. Clobetasol Propionate is classified as a Category C drug, meaning it may harm the fetus. Always consult your healthcare provider before using it during pregnancy.

8. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used while breastfeeding?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be passed into breast milk in small amounts. It should only be used during breastfeeding if absolutely necessary and prescribed by a doctor. Always consult your healthcare provider before using it while breastfeeding.

9. What should I do if I miss a dose of Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

If you miss a dose, apply it as soon as you remember, unless it’s close to the time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not apply extra to make up for a missed dose.

10. What are the serious side effects of Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Serious side effects are rare but may include:

• Severe allergic reactions, such as swelling, rash, and difficulty breathing
• Skin infections that worsen
• Thinning of the skin or easy bruising
• Signs of systemic absorption, such as weight gain, high blood sugar, or Cushing’s syndrome (with prolonged use)

If you experience any of these serious side effects, seek medical attention immediately.

11. How long can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should generally not be used for more than 2 weeks unless directed by your doctor. Prolonged use may lead to side effects such as skin thinning or systemic absorption of the corticosteroid.

12. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used on children?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should be used with caution in children, especially those under 2 years old, due to the potential for systemic absorption and side effects. Always follow the doctor’s instructions when using this medication in children.

13. What should I do if I accidentally swallow Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

If you accidentally swallow Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm, contact your healthcare provider or poison control immediately. Ingesting large amounts of corticosteroids can lead to serious side effects such as stomach issues or adrenal suppression.

14. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for acne?

This combination medication is not typically recommended for acne. While Clobetasol Propionate can reduce inflammation, the presence of Neomycin and Nystatin can sometimes cause skin irritation or worsen acne. Consult your doctor for appropriate acne treatment options.

15. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for insect bites?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used for insect bites if there is both inflammation and a bacterial or fungal infection present. However, for mild insect bites, other treatments like antihistamines or hydrocortisone may be more suitable.

16. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for rashes caused by allergies?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may help with allergic rashes that have become infected, but it is not the first-line treatment for allergies. Antihistamines or other corticosteroids may be preferred for treating allergy-related rashes.

17. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for fungal infections?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is effective in treating fungal infections, especially when complicated by bacterial infections. However, for simple fungal infections, other antifungals may be more appropriate.

18. How should I store Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Store this medication at room temperature, away from heat and moisture. Keep it in its original packaging and out of the reach of children. Do not freeze it.

19. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause skin thinning?

Yes, prolonged use of Clobetasol Propionate can cause skin thinning, which is a known side effect of potent corticosteroids. To minimize this risk, use the medication only as directed and for the shortest duration possible.

20. What should I do if Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm causes irritation?

If Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm causes irritation, discontinue use and consult your healthcare provider. They may recommend an alternative treatment or adjust your dosage.

21. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for sunburns?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should not be used on sunburned or damaged skin, as it may worsen irritation or sensitivity. Use soothing agents like aloe vera for sunburns instead.

22. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm on my scalp?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used on the scalp for conditions like psoriasis or seborrheic dermatitis, but it should be applied carefully and not excessively to avoid potential side effects.

23. How soon will I see results from Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm?

Results can be seen within a few days to a week, depending on the severity of the condition being treated. However, the full effects may take longer to appear, and consistent application is key to achieving the best results.

24. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for rosacea?

No, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is not recommended for rosacea. Using potent corticosteroids like Clobetasol Propionate on rosacea can make the condition worse.

25. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for a fungal infection on the nails?

This combination is typically not used for fungal nail infections. Nail fungal infections require oral antifungal medications, and topical treatments specific for nails.

26. How long should I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for dermatitis?

For dermatitis, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should be used for a short period (usually no more than two weeks), as directed by your healthcare provider, to avoid side effects such as skin thinning or resistance development.

27. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause weight gain?

While topical use of Clobetasol Propionate is unlikely to cause significant weight gain, prolonged use or overuse may lead to systemic absorption and potential side effects like Cushing’s syndrome, which can cause weight gain.

28. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause a rash?

In rare cases, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may cause an allergic reaction, resulting in a rash. If this occurs, discontinue use and contact your healthcare provider.

29. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause changes in skin color?

Clobetasol Propionate, a corticosteroid, may cause skin thinning and changes in pigmentation, especially with long-term use. If you notice changes in skin color, inform your doctor.

30. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for fungal infections of the mouth or throat?

No, this combination is not used for fungal infections in the mouth or throat. Oral antifungal medications like fluconazole are typically prescribed for such conditions.

31. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for diaper rashes?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may be used for diaper rashes that have both bacterial and fungal infections, but it should be used cautiously in infants. Consult a doctor before use.

32. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for eczema?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used for eczema, especially if there is a secondary bacterial or fungal infection. However, it should be used under medical supervision to avoid overuse.

33. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for allergic reactions?

While it may help with inflammation caused by allergic reactions, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is not the first choice for treating allergies. Antihistamines or other corticosteroids may be preferred.

34. Can I apply Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm to broken skin?

You should avoid applying Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm to broken or damaged skin unless directed by a doctor. It may be absorbed more rapidly and cause adverse effects.

35. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used on a rash from poison ivy?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used for a rash from poison ivy, especially if it has become infected, but it should be applied under the guidance of a healthcare provider.

36. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for a rash caused by medication?

If you develop a rash from a medication, you should consult your doctor before using Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm. Your doctor may recommend an alternative treatment or adjust your medication regimen.

37. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for bacterial infections?

Yes, Neomycin Sulphate in the combination helps treat bacterial infections. However, the underlying cause of the infection should be identified and treated accordingly.

38. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for fungal infections like athlete's foot?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may be used for athlete’s foot if a secondary bacterial infection is present. For fungal infections without bacterial involvement, other antifungals are usually more effective.

39. How do I know if Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is working?

You should notice a reduction in symptoms like inflammation, itching, and redness within a few days of using the medication. If there is no improvement or the condition worsens, consult your doctor.

40. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for contact dermatitis?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used to treat contact dermatitis, especially if it has become infected. Follow your doctor’s instructions for the best results.

41. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for dandruff?

If dandruff is caused by an underlying fungal or bacterial infection, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may be helpful. However, regular dandruff is usually treated with milder shampoos.

42. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for fungal infections of the skin?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is effective for treating skin fungal infections complicated by bacterial infections. Use as directed by your doctor to avoid overuse.

43. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause skin irritation?

Yes, skin irritation is a common side effect, especially if used excessively or on sensitive skin. If irritation occurs, discontinue use and consult your healthcare provider.

44. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for shingles?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm is not typically used for shingles. Antiviral medications are usually prescribed for shingles to reduce viral activity.

45. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm cause photosensitivity?

Topical corticosteroids like Clobetasol Propionate can increase sensitivity to sunlight. It’s important to avoid prolonged sun exposure and use sunscreen if using this medication.

46. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for hand eczema?

Yes, it can be used for hand eczema, especially if there is a bacterial or fungal infection present. However, avoid prolonged use on the hands to prevent skin thinning.

47. Can Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm be used for heat rash?

Heat rash is usually treated with cooling agents and mild corticosteroids. If the rash becomes infected, this combination may be helpful, but consult your doctor first.

48. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for a rash under my arms?

Yes, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm can be used under the arms for rashes, but use it sparingly and avoid prolonged use to prevent skin thinning and irritation.

49. Can I use Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm for rashes caused by perfume?

If the rash is caused by an allergic reaction to perfume, Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm may help reduce inflammation and prevent infection. However, discontinuing use of the perfume is also necessary.

50. Is Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm safe for pregnant women?

Clobeon Cream (0.5 mg+5 mg+1 Lac IU)/gm should only be used during pregnancy if absolutely necessary and under the guidance of a healthcare provider. The risks and benefits must be carefully considered.