Cefuroxime Axetil

Cefuroxime Axetil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefuroxime Axetil is a brand name. Its generic name is Cefuroxime.

Introduction

Cefuroxime Axetil is an antibiotic of the cephalosporin class used to treat a variety of bacterial infections. It can be used to treat a wide range of infections including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Uses For

Cefuroxime Axetil is used to treat a variety of bacterial infections, including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Mechanism of Action

Cefuroxime Axetil works by inhibiting the growth of bacteria by interfering with the bacterial cell wall synthesis. This prevents the bacteria from being able to replicate and leads to the eventual death of the bacteria.

How Long Does It Take To Work?

Cefuroxime Axetil typically begins to work within 48 hours of taking it, and symptoms should improve during that time. It is important to finish the full course of medication to prevent the re-emergence of the infection. If symptoms have not improved after 48 hours, contact your doctor.

Absorption

Cefuroxime Axetil is absorbed rapidly from the gastrointestinal tract and reaches peak concentrations in various organs and tissues, including the lungs, kidneys, prostate , and central nervous system.

Route of Elimination

Cefuroxime Axetil is eliminated mainly via the kidneys. It is also metabolized in the liver and excreted in the bile.

Dosage

The dosage of cefuroxime varies according to the infection being treated and the patient's age and weight. Generally, it is given as a single dose or in two divided doses given every 12 hours. For adults, the dosage ranges from 125 mg to 500 mg taken orally every 8 to 12 hours. For children, the dosage may be lower. It is important to follow your doctor's instructions.

Administration

Cefuroxime Axetil is usually taken orally. It can also be given intravenously, depending on the condition being treated. For oral administration, it is usually taken with a full glass of water. It can be taken with or without food.

Side Effect

Common side effects associated with cefuroxime include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, itching, and vaginal itching and discharge.

Toxicity

Cefuroxime Axetil is generally safe and well tolerable at recommended doses. However, it can cause certain toxic side effects when taken in high doses, including seizures, tremors, coma, and death.

Precautions

Cefuroxime Axetil should not be used in patients with a known allergy or hypersensitivity to cefuroxime, other cephalosporins, or penicillins. Cefuroxime Axetil should be used with caution in patients with a history of liver or kidney disease, or in those who are pregnant or breastfeeding.

Interaction

Cefuroxime Axetil can interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, warfarin (blood thinners), and certain antibiotics. Before taking cefuroxime, it is important to tell your doctor about any other medications you are taking to avoid potential interactions.

Disease Interactions

Cefuroxime Axetil can interact with certain diseases that can affect its efficacy. These include certain liver and kidney disease, diseases of the immune system, and conditions that affect the gastrointestinal tract. It is important to tell your doctor if you have any of these conditions before taking cefuroxime.

Drug Interactions

Cefuroxime Axetil can interact with certain medications, including other antibiotics, anticoagulants (blood thinners), nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and probenecid. It is important to tell your doctor about all medications you are taking.

Food Interactions

Cefuroxime Axetil may interact with certain foods. It should be taken at least two hours before or after taking calcium, magnesium, or iron supplements or antacids. Also, avoid alcohol while taking cefuroxime.

Pregnancy Use

Cefuroxime Axetil is generally safe to use during pregnancy, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime during pregnancy.

Lactation Use

Cefuroxime Axetil is usually safe to use during lactation, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime while breastfeeding.

Acute Overdose

An overdose of cefuroxime can cause serious side effects, including convulsions, dizziness, loss of consciousness, and even coma in some cases. It is important to seek medical attention immediately if you think you or someone else has taken an overdose of cefuroxime.

Contraindication

Cefuroxime Axetil is not to be used in patients with a known allergy or hypersensitivity to cefuroxime or other cephalosporins, or penicillins. Cefuroxime Axetil should also not be used in patients with a history of liver or kidney disease.

Use Direction

Cefuroxime Axetil should be taken as directed by your doctor. The dosage and frequency should not be exceeded or decreased without consulting your doctor. Taking cefuroxime with food or antacids can help reduce side effects.

Storage Condition

Cefuroxime Axetil should be stored at room temperature, below 30°C (86°F). Keep it in a tightly closed container away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of cefuroxime is about 0.4-0.5 L/Kg.

Half Life

Cefuroxime Axetil has a half-life of 2-3 hours.

Clearance

Cefuroxime Axetil is cleared from the body by both hepatic and renal pathways. The total clearance is 6.3 mL/min/kg.

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Some Frequently Asked Questions About Cefuroxime Axetil

What is Cefuroxime Axetil?

Cefuroxime Axetil is an antibiotic used to treat a wide variety of infections caused by bacteria. It works by stopping the growth of bacteria. It is available in brand and generic form.

What is Cefuroxime Axetil used to treat?

Cefuroxime Axetil is indicated to treat bacterial infections, including upper and lower respiratory tract, urinary tract, skin, and soft tissue infections.

Does Cefuroxime Axetil have side effects?

Cefuroxime Axetil may cause side effects such as nausea, vomiting, diarrhea, headache, or dizziness.

Can Cefuroxime Axetil be used to treat bronchitis?

Yes, Cefuroxime Axetil is commonly used to treat infections caused by bronchitis.

Is Cefuroxime Axetil a penicillin drug?

No, Cefuroxime Axetil is not a penicillin drug. It is a cephalosporin antibiotic.

Is Cefuroxime Axetil safe to use during pregnancy?

Cefuroxime Axetil is generally considered safe to use during pregnancy. However, it is recommended to consult a doctor before using any medication during pregnancy.

What is the recommended dosage of Cefuroxime Axetil?

The recommended dosage of Cefuroxime Axetil depends on the severity of the infection. It is recommended to consult a doctor for the exact dosage.

Can Cefuroxime Axetil be used in children?

Yes, Cefuroxime Axetil can be used in children. However, the dosage may need to be adjusted according to the severity of the infection.

Can Cefuroxime Axetil be taken with food?

Yes, Cefuroxime Axetil can be taken with food. However, it is recommended to take the medication with a full glass of water.

Does Cefuroxime Axetil cause weight gain?

No, Cefuroxime Axetil does not cause weight gain. However, it is recommended to consult a doctor if any unusual symptom is observed.

Is Cefuroxime Axetil an over the counter drug?

No, Cefuroxime Axetil is not available as an over the counter drug. It is available with a doctor's prescription.

What is the shelf life of Cefuroxime Axetil?

The shelf life of Cefuroxime Axetil is two years when stored under proper conditions.

Can Cefuroxime Axetil cause a yeast infection?

Yes, Cefuroxime Axetil may cause a yeast infection as a side effect.

What are the common side effects of Cefuroxime Axetil?

The common side effects of Cefuroxime Axetil include nausea, vomiting, dizziness, headache, or diarrhea.

Can Cefuroxime Axetil be used to treat a sinus infection?

Yes, Cefuroxime Axetil is commonly used to treat a sinus infection.

What are the contraindications of Cefuroxime Axetil?

Cefuroxime Axetil should not be used in patients with hypersensitivity to cephalosporin, penicillin, or any other medication.

Can Cefuroxime Axetil be taken long term?

Yes, Cefuroxime Axetil can be taken long term under the supervision of a doctor.

Can Cefuroxime Axetil be used to treat a urinary tract infection?

Yes, Cefuroxime Axetil is commonly used to treat a urinary tract infection.

Does Cefuroxime Axetil cause headache?

Yes, Cefuroxime Axetil may cause a headache as a side effect.

Can Cefuroxime Axetil be used to treat an ear infection?

Yes, Cefuroxime Axetil is commonly used to treat an ear infection.

What should be avoided while taking Cefuroxime Axetil?

Alcohol and grapefruit should be avoided while taking Cefuroxime Axetil.

What is the generic name of Cefuroxime Axetil?

The generic name of Cefuroxime Axetil is cefuroxime axetil.

Can Cefuroxime Axetil be used to treat pneumonia?

Yes, Cefuroxime Axetil can be used to treat pneumonia.

What are the pharmacological actions of Cefuroxime Axetil?

Cefuroxime Axetil has antibacterial, anti-inflammatory, and immunomodulatory actions.

What is the dose of Cefuroxime Axetil for adults?

The dose of Cefuroxime Axetil for adults is 250mg-500mg twice daily.

Can Cefuroxime Axetil be used to treat an STD?

Yes, Cefuroxime Axetil can be used to treat some Sexually Transmitted Diseases.

Does Cefuroxime Axetil interact with other medications?

Yes, Cefuroxime Axetil may interact with other medications such as aspirin and ibuprofen.

Can Cefuroxime Axetil cause diarrhea?

Yes, Cefuroxime Axetil may cause diarrhea as a side effect.

How long does it take for Cefuroxime Axetil to work?

It can take up to several days for Cefuroxime Axetil to start working. However, the exact time depends on the severity of the infection.

Does Cefuroxime Axetil cause drowsiness?

Yes, Cefuroxime Axetil may cause drowsiness as a side effect.

How is Cefuroxime Axetil administered?

Cefuroxime Axetil is administered orally in tablet or capsule form.

Can Cefuroxime Axetil be used to treat a strep throat?

Yes, Cefuroxime Axetil is commonly used to treat a strep throat.

Does Cefuroxime Axetil cause stomach upset?

Yes, Cefuroxime Axetil may cause stomach upset as a side effect.

Does Cefuroxime Axetil treat UTI?

Yes, Cefuroxime Axetil is commonly used to treat UTI (Urinary Tract Infection).

What is the dosage of Cefuroxime Axetil for children?

The dosage of Cefuroxime Axetil for children depends on the age and weight of the child. It is recommended to consult a doctor for the exact dosage.

Is Cefuroxime Axetil an antibiotic?

Yes, Cefuroxime Axetil is an antibiotic used to treat a wide variety of bacterial infections.

Is Cefuroxime Axetil effective against staphylococcus aureus?

Yes, Cefuroxime Axetil is effective against staphylococcus aureus.

What is the usual duration of treatment for Cefuroxime Axetil?

The usual duration of treatment with Cefuroxime Axetil is 5-7 days.

Does Cefuroxime Axetil have an expiration date?

Yes, Cefuroxime Axetil has an expiration date. It is recommended to check the expiration date before using the medication.

Can Cefuroxime Axetil be used to treat a sinus infection?

Yes, Cefuroxime Axetil is commonly used to treat a sinus infection.

Is Cefuroxime Axetil an over the counter drug?

No, Cefuroxime Axetil is not available as an over the counter drug. It is available with a doctor's prescription.