Caprolycin Injection

Caprolycin Injection 2 gm/10 ml

Caprolycin Injection 2 gm/10 ml, also known as ε-aminocaproic acid, is an antifibrinolytic medication used to prevent or reduce excessive bleeding in a variety of conditions. It is an organic compound found naturally in the body as well as in several foods, including legumes, nuts, meat, eggs and seafood.

Uses

Caprolycin Injection 2 gm/10 ml is used to stop or reduce excessive bleeding. It is used to prevent bleeding from acute tissue trauma, surgery or during certain medical procedures, for example, endoscopic procedures.

Brand Name	Caprolycin
Type	Injection
Weight	2 gm/10 ml
Generic	Aminocaproic acid
Manufacturer	Pacific Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Caprolycin Injection 2 gm/10 ml works by blocking the breakdown of fibrin, a protein that is essential in the process of blood clotting. This reduces the amount of fibrin that is available to form a clot, thereby decreasing the amount of bleeding.

How Long Does It Take to Work?

The effects of aminocaproic acid usually occur within minutes, which is why it is recommended to be taken immediately before or after a procedure.

Absorption

Caprolycin Injection 2 gm/10 ml is rapidly absorbed from the gastrointestinal tract and is well absorbed after oral administration.

Route of Elimination

Caprolycin Injection 2 gm/10 ml is largely eliminated through the kidneys in the form of its inactive metabolites. It is also minimally metabolized by the liver.

Dosage

Dosage of Aminocaproic acid must be adjusted to individual cases according to the severity of the hemmohagic event. It must however born in mind that Aminocaproic acid cleared rapidly by renal rough, so that administration must be repeated every 4-6 hours. The average dose is 8-16 gm a day.i.e. 1 ampule of Aminocaproic acid according to the case, every 6 hours.

Aminocaproic acid is equally effective by mouth and intarvenous injection. In cases of particular severity, or when it is sought to obtain a high blood concentration quickly it is advisable to start treatment by intravenous rough, with slow injection of two Aminocaproic acid ampules with an interval of 30-60 minutes between them, continuing with divided doses until a dosage of 20-25 grams in the 24 hour is reached.

In any case, administration of the drug must be continued until complete cessation of all symptoms. Aminocaproic acid could be intravenously administered, following suitable dilution in Physiological solution.

The recommended dosage of aminocaproic acid for adults is 3.5-17.5 g/day taken orally in two divided doses or as a single dose intravenously. The dose should be adjusted according to the diagnosis and the severity of bleeding. For children, the dose and duration of administration should be prescribed by a doctor.

Administration

Caprolycin Injection 2 gm/10 ml is usually taken orally, in the form of tablets or capsules, or it can also be given as an intravenous injection. It is important to follow your doctor's instructions when taking aminocaproic acid.

Side Effect

The most common side effects of aminocaproic acid are nausea, abdominal pain, vomiting, diarrhea, and headache. Other side effects may include allergic reactions, lowered platelet count, liver and kidney damage, and breathing difficulty.

Toxicity

Caprolycin Injection 2 gm/10 ml overdose can be dangerous and may cause serious, life-threatening side effects. Symptoms of overdose may include nausea, vomiting, abdominal pain, confusion, dizziness, loss of appetite, drowsiness, and convulsions.

Precautions

Before taking aminocaproic acid, it is important to inform your doctor about any allergies and medical conditions you may have. It should also be avoided in patients who are pregnant or breastfeeding. Additionally, it should be used with caution in patients with kidney or liver disease.

Interaction

Caprolycin Injection 2 gm/10 ml can interact with certain medications, such as anticoagulants, nonsteroidal anti-inflammatory drugs, and other anti-fibrinolysis medications. Additionally, it can interact with certain herbal supplements and vitamins, such as ginkgo biloba, garlic, vitamin E, and vitamin A.

Disease Interaction

Caprolycin Injection 2 gm/10 ml may interact with certain diseases or medical conditions, such as liver disease, renal failure, or bleeding disorders. Additionally, it may interact with certain medications used to treat these conditions, such as warfarin.

Drug Interaction

Caprolycin Injection 2 gm/10 ml can interact with certain drugs, such as anticoagulants, nonsteroidal anti-inflammatory drugs, and other anti-fibrinolysis medications. Additionally, it can interact with certain herbal supplements and vitamins, such as ginkgo biloba, garlic, vitamin E, and vitamin A.

Food Interactions

Caprolycin Injection 2 gm/10 ml can interact with certain foods, such as citrus fruits, dairy products, and grapefruit juice. It is important to limit the consumption of these foods while taking aminocaproic acid.

Pregnancy Use

Caprolycin Injection 2 gm/10 ml should be used with caution in pregnant women, as it may present risks to the fetus. If you are pregnant, it is important to consult your doctor before taking this medication.

Lactation Use

Caprolycin Injection 2 gm/10 ml should be avoided in nursing mothers, as its safety in this population is not established.

Acute Overdose

Acute overdose of aminocaproic acid can cause life-threatening reactions. If you suspect an overdose, seek medical attention immediately.

Contraindication

Caprolycin Injection 2 gm/10 ml should not be taken if you are sensitive or allergic to it. Additionally, it should not be used in patients with a history of bleeding disorders, such as hemophilia, or in patients who are taking anticoagulant or anti-fibrinolytic drugs.

Use Direction

Caprolycin Injection 2 gm/10 ml should be taken exactly as prescribed by your doctor. Do not take a larger or smaller dose than recommended, and do not take the medication for a longer period of time than directed.

Storage Condition

Caprolycin Injection 2 gm/10 ml should be stored in a cool, dry place, at room temperature, away from light and moisture. It should also be kept out of the reach of children. Do not freeze or refrigerate this medication.