Canstat Oral Suspension

Canstat Oral Suspension 100000 unit/ml Introduction

Canstat Oral Suspension 100000 unit/ml is a polyene antifungal medication used to treat superficial fungal infections of the skin, nails, and mouth. It is typically administered topically through a cream, ointment, powder, or suspension, as long as it is not taken by mouth, and it has been approved by the U.S. Food and Drug Administration (FDA).

Matain Uses

Canstat Oral Suspension 100000 unit/ml is used to treat various superficial or cutaneous fungal infections in humans caused by fungi, such as Candida albicans, Pityrosporum ovale, and Trichophyton species. It is sometimes used to prevent and treat fungal infections in the kidney, penis, vagina, and urinary tract. It is also used off-label to treat oral thrush (oral candidiasis).

Brand Name	Canstat
Type	Oral Suspension
Weight	100000 unit/ml
Generic	Nystatin
Manufacturer	Jayson Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Canstat Oral Suspension 100000 unit/ml works by inhibiting the formation of sterols needed for cell wall production in fungi. As the cell wall is destroyed, the fungi is unable to grow or reproduce, thereby halting its progression and reverting to its natural state as a dormant organism.

How Long Does it Take to Work?

Canstat Oral Suspension 100000 unit/ml is a rapid-acting antifungal medication; it is typically effective within 3-5 days of usage, although the effectiveness of the medication may vary based on the severity of the infection.

Absorption

Canstat Oral Suspension 100000 unit/ml has low systemic absorption (less than 0.4%) when used topically and is rapidly cleared from the blood. The peak serum concentration of the drug is achieved within 4-24 hours after topical administration.

Route of Elimination

Canstat Oral Suspension 100000 unit/ml is primarily eliminated in the feces, with up to 95% of the drug being excreted in the bile within 48 hours of administration. The remainder of the drug is excreted in the urine.

Dosage

For topical use, the recommended dose of nystatin is 100,000 to 200,000 international units per gram of the cream or ointment applied twice daily for 14 days. For oral or intravesical use, the recommended dose of nystatin is 10,000 to 100,000 international units per day, divided and taken 3-4 times daily.

Administration

Canstat Oral Suspension 100000 unit/ml is typically administered topically through a cream, ointment, powder, or suspension, as long as it is not taken by mouth. Oral or intravesical nystatin should be taken with meals or immediately after meals to maximize the absorption of the drug.

Side Effects

The most common side effects of topical nystatin are burning, stinging, irritation, and itching at the site of application. Other possible side effects include headache, dizziness, and nausea.

Toxicity

Canstat Oral Suspension 100000 unit/ml is generally considered safe and non-toxic. If irritation or other symptoms persist, contact a healthcare professional until proper medical advice can be acquired.

Precautions

Canstat Oral Suspension 100000 unit/ml should not be used for more than 14 consecutive days and should not be used in the eyes without consulting with a healthcare professional. Patients should not wear contact lenses while using nystatin.

Interaction

Canstat Oral Suspension 100000 unit/ml has no known clinically significant pharmacokinetic interactions with other medications.

Disease Interaction

Canstat Oral Suspension 100000 unit/ml is not recommended for patients with kidney or liver dysfunction, as it may worsen the condition.

Drug Interactions

Canstat Oral Suspension 100000 unit/ml has no known clinically significant pharmacokinetic interactions with other medications.

Food Interactions

Canstat Oral Suspension 100000 unit/ml is not known to interact with foods.

Pregnancy Use

Canstat Oral Suspension 100000 unit/ml is generally regarded as safe for use during pregnancy, although caution should be taken if it is used in large doses.

Lactation Use

Canstat Oral Suspension 100000 unit/ml is likely to be safe for use during breastfeeding, although caution should be taken if it is used in large doses.

Acute Overdose

An acute overdose of nystatin is unlikely, as the drug is rapidly cleared from the body. No specific antidote is available.

Contraindication

Canstat Oral Suspension 100000 unit/ml is contraindicated in patients who are hypersensitive to it or any of its components.

Use Direction

Canstat Oral Suspension 100000 unit/ml should be applied topically to affected areas, paying particular attention to avoid contact with the eyes or mouth. Oral or intravesical nystatin should be taken by following instructions provided by a healthcare professional and should not be taken without consulting a professional.

Storage Conditions

Canstat Oral Suspension 100000 unit/ml should be kept in its original container and stored at room temperature, away from direct sunlight, heat, and moisture.