Calcium Carbonate

Calcium Carbonate

Calcium carbonate is a chemical compound consisting of calcium, carbon, and oxygen, and is the active ingredient found in antacid medications. It is used to treat heartburn, indigestion, and other forms of stomach upset. It is also commonly used to supplement calcium levels in individuals who have low calcium diets or who may have calcium absorbed inadequately from foods.

Uses for Calcium Carbonate

Calcium carbonate is used to help treat a variety of conditions, including heartburn, upset stomach, and acid indigestion. It can also be used to supplement calcium in individuals who have low calcium diets. Additionally, calcium carbonate is often used as an antacid for people with symptoms of gastroesophageal reflux.

Brand Name	Calcium Carbonate
Type
Weight
Generic	Calcium Carbonate
Manufacturer
Available in	English বাংলা

Mechanism of Action

When taken as an antacid, calcium carbonate works by neutralizing stomach acid. It binds to hydrogen and chlorine ions in the stomach, forming calcium chloride and carbonic acid. This helps to reduce heartburn and acid indigestion.

How Long Does it Take to Work?

Calcium carbonate begins to work as an antacid almost immediately after ingestion. It typically takes between five and ten minutes for it to begin working.

Absorption

Calcium carbonate is rapidly absorbed from the gut into the bloodstream. It has a bioavailability of approximately 35%, meaning that the amount of calcium carbonate absorbed as an antacid is approximately 35% of the total taken.

Route of Elimination

Calcium carbonate is eliminated from the body primarily through the kidneys. Approximately 95% is eliminated in the urine with the remainder being eliminated via the feces.

Dosage

The recommended dose of calcium carbonate is 500mg to 1000mg taken between meals and at bedtime, not exceeding 6000mg in total in 24 hours. The dose should be taken with a full glass of water (8oz) to help ensure full absorption in the stomach.

Administration

Calcium carbonate can be taken orally as a tablet, capsule, or powder. It can also be mixed into a beverage or taken with food or other medications.

Side Effects

Common side effects of calcium carbonate include constipation, nausea, and upset stomach. Other more serious side effects may include increased risk of kidney stones, bone fractures, and heart attack due to high calcium levels in the blood.

Toxicity

Calcium carbonate is generally considered safe and has a low risk of toxicity. The only risk of toxicity is if very large doses are taken in any one day, as this may lead to increased calcium levels in the blood which can be fatal.

Precaution

Patients should consult their physician prior to taking calcium carbonate. It should not be taken if you have a history of high calcium levels in your blood or if you are taking any prescription medications that can interact with calcium carbonate.

Interaction

Calcium carbonate can interact with medications that reduce stomach acid, such as proton pump inhibitors or H2 antagonists. It can also interact with magnesium antacids or medications that contain aluminum, as this may reduce the overall effectiveness of calcium carbonate.

Disease Interaction

Calcium carbonate may interfere with the absorption of certain medications used to treat kidney disease, as well as medications used to treat heart disease. Additionally, it may increase the risk of kidney stones in individuals who have history of kidney disease.

Drug Interaction

Calcium carbonate can interact with medications that reduce stomach acid such as proton pump inhibitors or H2 antagonists. It can also interact with medications containing aluminum, magnesium, iron, or bismuth which may reduce the effectiveness of the calcium carbonate and make it less effective.

Food Interactions

Calcium carbonate may reduce the absorption of certain vitamins, minerals, or other medications if taken at the same time. It should be taken at least 2 hours before or after a meal.

Pregnancy Use

Calcium carbonate is generally safe to use during pregnancy and there are no known risks associated with taking it during this time. However, pregnant women should always consult their physician prior to taking any medications.

Lactation Use

Calcium carbonate is not known to cause any adverse effects in breastfeeding women and is safe to use while breastfeeding. However, as always, it is recommended that breastfeeding women consult their physicians prior to taking any medications.

Acute Overdose

An acute overdose of calcium carbonate is rare, but may cause nausea, vomiting, abdominal discomfort, and malaise. High levels of calcium in the blood can cause coma and even be fatal. It is important to contact a healthcare provider immediately if an acute overdose of calcium carbonate is suspected.

Contraindication

Calcium carbonate should not be taken if you have a history of high calcium levels in the blood, kidney disease, or if you are taking any prescription medications that can interact with calcium carbonate. It should also not be taken if you are pregnant, breastfeeding, or have other medical conditions.

Use Direction

Calcium carbonate should be taken orally with a full glass of water (8oz). The recommended dose is 500mg to 1000mg taken between meals and at bedtime, not exceeding 6000mg in total in 24 hours. It should be taken at least 2 hours before or after a meal.

Storage Condition

Calcium carbonate should be stored at room temperature, in a dark and dry place, away from direct sunlight and away from children and pets.

Volume of Distribution

The volume of distribution for calcium carbonate is 0.57 L/kg.

Half Life

The half-life of calcium carbonate is approximately 1.5 hours.

Clearance

The clearance of calcium carbonate is 9.6 L/hr/kg.

See in details version Calcium Carbonate also Calcium Carbonate in bangla

Some Frequently Asked Questions About Calcium Carbonate

1. What is Calcium Carbonate ?

Calcium Carbonate is a dietary supplement and antacid used to treat calcium deficiency and acid-related conditions.

2. What are the uses of Calcium Carbonate ?

It is used for:

• Calcium supplementation
• Preventing and treating osteoporosis
• Relieving acid indigestion and heartburn
• Managing hypocalcemia (low calcium levels)

3. How does Calcium Carbonate work?

It provides calcium for bone health and neutralizes stomach acid when used as an antacid.

4. What is the recommended dosage for Calcium Carbonate ?

The dosage depends on the condition, but typically:

• For calcium supplementation: 500–1,500 mg per day
• For acid reflux: 750–2,000 mg per dose

5. Can I take Calcium Carbonate with food?

Yes, it is best absorbed when taken with food.

6. What are the common side effects of Calcium Carbonate ?

Common side effects include:

• Constipation
• Bloating
• Gas
• Nausea

7. Can I take Calcium Carbonate if I have kidney disease?

Patients with kidney disease should consult a doctor before use, as excess calcium may cause kidney stones.

8. Does Calcium Carbonate interact with other medications?

Yes, it can interact with:

• Iron supplements
• Thyroid medications
• Certain antibiotics (e.g., tetracyclines, fluoroquinolones)
• Bisphosphonates (used for osteoporosis)

9. Can Calcium Carbonate be taken during pregnancy?

Yes, it is generally safe during pregnancy but should be taken as per a doctor's recommendation.

10. Is Calcium Carbonate safe for children?

Yes, but the dosage should be determined by a pediatrician.

11. Can I take Calcium Carbonate with milk?

Yes, but excessive calcium intake from supplements and dairy may lead to hypercalcemia.

12. Can Calcium Carbonate help with osteoporosis?

Yes, it helps maintain bone density and reduces the risk of osteoporosis.

13. How long does it take for Calcium Carbonate to work?

As an antacid, it works within minutes. For calcium supplementation, benefits develop over weeks to months.

14. Can I take Calcium Carbonate every day?

Yes, but do not exceed the recommended dose to avoid excess calcium buildup.

15. What happens if I take too much Calcium Carbonate ?

Overdose symptoms include:

• Hypercalcemia (high calcium levels)
• Kidney stones
• Nausea and vomiting
• Confusion

16. Can Calcium Carbonate cause kidney stones?

Excessive intake may increase the risk of kidney stones.

17. Is Calcium Carbonate the same as calcium citrate?

No, calcium citrate is absorbed better without food, while calcium carbonate requires food for optimal absorption.

18. Can I take Calcium Carbonate if I have acid reflux?

Yes, it works as an antacid to relieve heartburn and acid reflux.

19. Does Calcium Carbonate help with muscle cramps?

Yes, calcium deficiency can cause muscle cramps, so supplementation may help.

20. Can I take Calcium Carbonate and Vitamin D together?

Yes, Vitamin D helps improve calcium absorption.

21. Can Calcium Carbonate cause diarrhea?

It usually causes constipation rather than diarrhea.

22. Is Calcium Carbonate vegan?

It depends on the source. Some formulations come from animal sources (e.g., oyster shells), while others are synthetic.

23. Can I crush Calcium Carbonate tablets?

Yes, unless they are extended-release tablets.

24. Does Calcium Carbonate expire?

Yes, always check the expiration date before use.

25. Can I take Calcium Carbonate before surgery?

Inform your doctor before taking any supplement before surgery.

26. Can Calcium Carbonate be taken at night?

Yes, but for better absorption, take it with a meal.

27. Does Calcium Carbonate affect blood pressure?

It may help regulate blood pressure but should be used under medical supervision.

28. Can Calcium Carbonate prevent osteoporosis?

Yes, it helps maintain strong bones and prevent osteoporosis.

29. Can Calcium Carbonate cause weight gain?

No, it does not cause weight gain.

30. Is Calcium Carbonate used in food?

Yes, it is used as a food additive and preservative.

31. Can Calcium Carbonate improve dental health?

Yes, it supports strong teeth and helps prevent enamel erosion.

32. Can Calcium Carbonate cause drowsiness?

No, it does not cause drowsiness.

33. Can I take Calcium Carbonate with caffeine?

Caffeine may reduce calcium absorption, so limit intake.

34. Does Calcium Carbonate improve nail health?

Yes, calcium deficiency can lead to brittle nails.

35. Can Calcium Carbonate be taken with aspirin?

Consult a doctor, as calcium may interfere with aspirin absorption.

36. Does Calcium Carbonate support heart health?

It may support heart function, but excessive intake can cause issues.

37. Can I take Calcium Carbonate if I have lactose intolerance?

Yes, it can provide calcium without consuming dairy.

38. Does Calcium Carbonate help with acid indigestion?

Yes, it neutralizes stomach acid and relieves indigestion.

39. Can Calcium Carbonate be used for leg cramps?

It may help if the cramps are due to calcium deficiency.

40. Is Calcium Carbonate good for hair growth?

It supports overall health, but there is limited evidence linking it directly to hair growth.

41. Can I take Calcium Carbonate if I have anemia?

Yes, but avoid taking it with iron supplements, as it may reduce iron absorption.

42. Does Calcium Carbonate help with nerve function?

Yes, calcium is essential for nerve signal transmission.

43. Can I take Calcium Carbonate with warfarin?

Consult your doctor, as calcium may interact with blood thinners.

44. Can I use Calcium Carbonate for bone fractures?

Yes, it helps in bone healing.

45. Can Calcium Carbonate be used for gastric ulcers?

It may provide temporary relief but is not a primary treatment.

46. Does Calcium Carbonate improve immune function?

It supports general health but is not directly linked to immunity.

47. Can I take Calcium Carbonate with magnesium?

Yes, they are often combined for better absorption.

48. Does Calcium Carbonate expire?

Yes, always check the expiration date before use.

49. Can Calcium Carbonate be taken with protein shakes?

Yes, but calcium absorption may be affected by high protein intake.

50. Can I take Calcium Carbonate with zinc?

Yes, but take them at different times for better absorption.