Bisoprolol Hemifumarate

Introduction

Bisoprolol Hemifumarate is a beta blocker medication that is used to treat high blood pressure, angina, heart failure, and arrhythmia. It is a type of medication that is classified as an anti-hypertensive, which is a medication that helps lower blood pressure. It acts by blocking the action of a certain nature chemical in the body that can cause the heart to beat quickly or erratically, helping the heart to beat more regularly and with less force.

Uses

Bisoprolol Hemifumarate is used to treat high blood pressure, angina, heart failure, and arrhythmia. It can also be used in combination with certain other medications to treat chest pain and heart attack.

Brand Name	Bisoprolol Hemifumarate
Type
Weight
Generic	Bisoprolol Hemifumarate
Manufacturer
Available in	English বাংলা

Mechanism of Action

Bisoprolol Hemifumarate works by blocking the action of a certain nature chemical in the body that can cause the heart to beat too quickly or erratically, helping the heart to beat more regularly and with less force. By blocking the action of this certain nature chemical, Bisoprolol Hemifumarate helps to lower blood pressure and reduce the risk of stroke, heart attack, and other cardiovascular events.

How Long Does it Take to Work?

Bisoprolol Hemifumarate usually takes around 6 to 8 weeks to lower blood pressure and reduce symptoms of angina, heart failure, and arrhythmia. During this time, it is important to follow your doctor's instructions in managing your blood pressure, lifestyle, and diet.

Absorption

Bisoprolol Hemifumarate is quickly and completely absorbed in the gastro-intestinal tract. The peak effect is seen in about an hour after its administration.

Route of Elimination

Bisoprolol Hemifumarate is mainly metabolised in the liver and excreted into the bile. A small amount may be eliminated in the urine as unchanged drug and/or metabolites.

Dosage

Adult: In the treatment of mild to moderate hypertension, Bisoprolol fumarate must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily either added to a diuretic or alone. If the response to 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily. An appropriate interval for dose titration is 2 weeks. Increasing the dose beyond 20 mg once daily produces only a small incremental benefit.

Children: Safety and effectiveness in children have not been established.

Patients With Renal or Hepatic Impairment: In patients with hepatic impairment (hepatitis or cirrhosis) or renal dysfunction (creatinine clearance less than 40 mL/min) as in other patients, the initial daily dose should be 5 mg. Because of the possibility of accumulation, caution must be used in dose titration. Since limited data suggest that bisoprolol fumarate is not dialysable, drug replacement is not necessary in patients undergoing dialysis.

Geriatrics: In the elderly, it is not usually necessary to adjust the dose, unless there is also significant renal or hepatic dysfunction Bisoprolol Hemifumarate is available as an oral tablet, oral capsule, and an oral solution. It is also available as an oral suspension for pediatrics and special populations. The usual starting dose for adults is 5 mg once daily. Improper or excessive administration may result in serious side effects or toxicity.

Administration

Bisoprolol Hemifumarate should be taken as prescribed by your doctor. The usual starting dose is 5 mg once daily, taken with or without food. It is important to take the medication as prescribed and at the same time every day, as this helps to keep your blood pressure under control. If you forget to take your dose, take it as soon as you can, but do not take more than one dose in a day.

Side Effect

The most common side effects of Bisoprolol Hemifumarate are dizziness, headache, fatigue, diarrhea, nausea, and vomiting. Other side effects that have been reported include stomach pain, chest pain, difficulty breathing, dry mouth, itching, rash, and difficulty sleeping. If any of these side effects worsen or persist, you should contact your doctor.

Toxicity

Bisoprolol Hemifumarate can cause a severe drop in blood pressure or an irregular heartbeat if taken in excessive doses. If any of these symptoms occurs, the patient should seek immediate medical attention.

Precautions

Before taking Bisoprolol Hemifumarate , it is important to tell your doctor about all medications you are currently taking, including over-the-counter medicines, vitamins, and herbal supplements. Bisoprolol Hemifumarate may interact with certain medications, so it is important to let your doctor know all other medicines you are taking. It is also important to tell your doctor if you have any allergies, especially to beta-blockers or other medications. It is also important to tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Interaction, Disease Interaction, Drug Interaction, Food Interactions

Bisoprolol Hemifumarate may interact with certain medications, so it is important to tell your doctor about all other medications you are taking. This includes over-the-counter medicines, vitamins, and herbal supplements. Additionally, Bisoprolol Hemifumarate may interact with certain foods, such as grapefruit and grapefruit juice. Alcohol use should also be avoided while taking this medication.

Pregnancy Use

Bisoprolol Hemifumarate should not be used during pregnancy unless specifically advised by your doctor. If you become pregnant while taking this medication, contact your doctor immediately.

Lactation Use

Bisoprolol Hemifumarate should not be used by breastfeeding mothers unless specifically advised by your doctor. If you are breastfeeding while taking this medication, contact your doctor immediately.

Acute Overdose

If an overdose of Bisoprolol Hemifumarate is suspected, contact your doctor or local poison control center immediately. Symptoms of an overdose may include a slow or irregular heartbeat, difficulty breathing, dizziness, fainting, and seizures.

Contraindication

Bisoprolol Hemifumarate should not be used in patients who are allergic to beta-blockers or any of its active ingredients. Additionally, Bisoprolol Hemifumarate should not be used in patients with certain conditions, such as asthma, certain arrhythmias, kidney problems, and metabolic acidosis.

Use Direction

Bisoprolol Hemifumarate should be taken exactly as prescribed by your doctor. The usual starting dose is 5 mg once daily, taken with or without food. It is important to take the medication as prescribed and at the same time every day, as this helps to keep your blood pressure under control. If you forget to take your dose, take it as soon as you can, but do not take more than one dose in a day.

Storage Condition

Bisoprolol Hemifumarate should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medicines out of the reach of children and pets.