Benzoyl Peroxide

Introduction

Benzoyl peroxide is a compound used in various cosmetics and medications as an antiseptic and anti-inflammatory agent. It is used to treat mild to moderate acne, seborrhea and other skin disorders.

Uses for

Benzoyl peroxide is used to treat a variety of skin disorders, such as mild to moderate acne, seborrheic dermatitis, and psoriasis. It is also used to reduce surface bacteria on the skin, which can lead to bacterial colonization and infection.

Brand Name	Benzoyl Peroxide
Type
Weight
Generic	Benzoyl Peroxide
Manufacturer
Available in	English বাংলা

Mechanism of Action

Benzoyl peroxide works by disrupting bacteria which require oxygen to survive, converting molecular oxygen to free radicals which are toxic to the bacteria. It also has anti-inflammatory properties, making it useful for skin conditions such as acne.

How long does it take to work

The effects of benzoyl peroxide typically begin within the first few days of use. However, it can take up to 8 weeks for the full effects to become apparent and results vary among individuals.

Absorption

Benzoyl peroxide is absorbed through the skin and into the bloodstream. It is efficiently metabolized by the liver and eliminated from the body through the kidneys.

Route of Elimination

Benzoyl peroxide is eliminated from the body primarily through urine. It is also excreted in the feces and breath.

Dosage

Shake well before using. It is recommended that therapy be initiated with Benzoyl Peroxide, washing the affected areas once a day during the first week, and twice a day thereafter as tolerated. Wet skin areas to be treated; apply Benzoyl Peroxide Wash, work to a full lather, rinse thoroughly and pat dry. Frequency of use should be adjusted to obtain the desired clinical response. Close cap tightly after use.

Children: Safety and effectiveness in children below the age of 12 have not been established. The usual adult dose of benzoyl peroxide is 10-20mg every 12 hours. For treating acne, it is often recommended to start with a twice-daily application of a 2.5-5% benzoyl peroxide gel or cream.

Administration

Benzoyl peroxide is typically administered topically, and should be applied to the affected area twice daily. It is important to wash your hands immediately after application, and to avoid contact with the eyes, mouth, and lips.

Side Effect

The most common side effects of benzoyl peroxide are dryness and itching. This can be alleviated by using a moisturizing product after application. Other potential side effects include redness, burning, scaling, and blistering.

Toxicity

Benzoyl peroxide is safe at the recommended doses and generally well tolerated. Rarely, severe skin irritation may occur. In such cases, discontinue use and consult with a physician.

Precautions

It is important to use benzoyl peroxide cautiously when it is used along with other topical medications, as this may increase the risk of skin irritation. If irritation is experienced, reduce the frequency of application or stop using the medication.

Interaction

Benzoyl peroxide may interact with other medications applied to the skin or taken orally. Before using benzoyl peroxide, consult with your doctor or pharmacist to ensure that it is safe to use with other medications.

Disease Interaction

Benzoyl peroxide may worsen certain skin conditions and should be used with caution in those with a known history of skin disorders. It is also not recommended for pregnant or nursing women or those with impaired liver or kidney function.

Drug Interaction

Benzoyl peroxide may interact with other medications, particularly those applied to the skin. It is important to report any prescription or over-the-counter medications you are taking or have recently taken to your doctor or pharmacist prior to using benzoyl peroxide.

Food Interactions

There are no known food or drug interactions associated with benzoyl peroxide. However, certain foods may worsen symptoms of acne, so it is important to eat a healthy diet and avoid foods that are known to be triggers.

Pregnancy Use

Benzoyl peroxide should not be used during pregnancy. Consult with your doctor before using any medication if you are pregnant or may become pregnant.

Lactation Use

Benzoyl peroxide should not be used during lactation. Consult with your doctor before using any medication if you are breastfeeding.

Acute Overdose

An overdose of benzoyl peroxide can result in symptoms such as redness, burning, itching, or stinging. If an overdose is suspected, contact your doctor or the poison control center immediately.

Contraindication

Benzoyl peroxide should not be used by individuals with a known hypersensitivity to the ingredients or by those with a history of skin disorders. It should also be used with caution in individuals with impaired liver or kidney function.

Use Direction

Benzoyl peroxide should be applied to the affected area twice daily, typically in the morning and evening. For best results, use a mild cleanser and lukewarm water before applying the medication.

Storage Condition

Benzoyl peroxide should be stored at room temperature in an area away from direct sunlight, moisture, and extreme temperatures. It should be kept out of the reach of children and pets.