Azilsartan Medoxomil

Introduction

Azilsartan Medoxomil is an angiotensin II receptor antagonist that is used to treat high blood pressure. It is an oral medication that comes as a tablet and is intended to be taken twice a day.

Uses For

Azilsartan Medoxomil is used in the long-term management of high blood pressure and hypertension. It is often used in combination with other medications in order to control blood pressure levels. It can also be used in the treatment of certain types of kidney disease and heart failure.

Brand Name	Azilsartan Medoxomil
Type
Weight
Generic	Azilsartan Medoxomil
Manufacturer
Available in	English বাংলা

Mechanism of Action

Azilsartan Medoxomil works by blocking the action of angiotensin II, a hormone that helps regulate blood pressure. It does this by binding to the angiotensin II receptors and preventing the hormone from binding to them. This reduces the amount of angiotensin II in the bloodstream and improves the overall circulation.

How Long Does It Take To Work?

Azilsartan Medoxomil is an effective medicine, and many users start experiencing a reduction in their blood pressure within just a few weeks of beginning treatment. However, the full effects of the drug may take longer to appear, so it is important to be patient and continue taking the medication as prescribed.

Absorption & Route of Elimination

Azilsartan Medoxomil is well absorbed from the gastrointestinal tract. It is then eliminated from the body primarily through urination.

Dosage

The recommended dose in adults is 80 mg taken orally once daily. Consider a Starting dose of 40 mg for patients who are treated with high doses of diuretics. If blood pressure is not controlled with Azilsartan alone, additional blood pressure reduction can be achieved by taking Azilsartan with other antihypertensive agents. The dosage of Azilsartan Medoxomil will vary for different patients. It is important to consult a doctor or pharmacist to determine the exact dose for each individual. The usual starting dosage is 40mg taken orally once daily, but it may be increased up to 80mg depending on the patient's response.

Administration

Azilsartan Medoxomil is taken by mouth, usually with or without food. It should be taken exactly as prescribed by the doctor and not changed without consulting a healthcare professional.

Side-Effect

The most common side-effects of Azilsartan Medoxomil include headache, dizziness, fatigue, and nausea. More serious side-effects can include swelling, rapid or irregular heartbeat, and low blood pressure.

Toxicity

Azilsartan Medoxomil is generally safe when taken as prescribed. However, if it is taken in large doses, it can be toxic and can lead to an increased risk of side-effects and even death.

Precaution

Patients taking Azilsartan Medoxomil should avoid becoming pregnant or breast-feeding while taking the medication. They should also avoid taking other medications that contain similar active ingredients without consulting a doctor. Those who have a history of heart problems, kidney problems, or an allergy to angiotensin receptor blockers should speak to their doctor before using this medication.

Interactions

Azilsartan Medoxomil can potentially interact with certain medications, including NSAIDs, anticonvulsants, and potassium-sparing diuretics such as spironolactone. It is important to consult a doctor before taking any of these medications together.

Disease Interactions

Patients with liver or kidney disease should speak to their doctor before taking Azilsartan Medoxomil , as the medicine could potentially cause further complications.

Drug Interactions

Azilsartan Medoxomil can interact with certain drugs, leading to increased blood pressure. These drugs include lithium, diuretics, certain anticonvulsants, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

Azilsartan Medoxomil may interact with certain food products, leading to increased or decreased effectiveness. These include foods that are high in potassium or salt, as well as alcohol.

Pregnancy Use

Azilsartan Medoxomil should not be used by pregnant women due to the potential risks to the unborn baby.

Lactation Use

Azilsartan Medoxomil may pass into breast milk, so it should be avoided by breastfeeding mothers.

Acute Overdose

In the event of an acute overdose of Azilsartan Medoxomil , symptoms such as dizziness, fainting, and low blood pressure may occur. Treatment typically involves supportive care and monitoring of vital signs.

Contraindication

Azilsartan Medoxomil is contraindicated in patients with known hypersensitivity to the medication. It should also not be used in pregnant women or those who are breastfeeding.

Use Direction

Azilsartan Medoxomil should be taken exactly as prescribed by a doctor. Patients should take one tablet twice daily, with or without food. The tablets should also never be crushed or chewed as this could affect the speed and effectiveness of the drug.

Storage Condition

Azilsartan Medoxomil should be stored at room temperature away from direct heat and moisture. It should also be kept out of the reach of children.

Volume of Distribution

The volume of distribution of Azilsartan Medoxomil is 17 L/kg.

Half Life

The half-life of Azilsartan Medoxomil is 7 hours.

Clearance

The clearance of Azilsartan Medoxomil is 10 mL/min/kg.

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Some Frequently Asked Questions About Azilsartan Medoxomil