Introduction
Meclizine+Pyridoxine is a prescription medication used to treat symptoms of motion sickness such as nausea, vomiting, dizziness, and headache. It is a combination of meclizine hydrochloride, an antihistamine, and pyridoxine (vitamin B6), which helps to reduce the drowsiness associated with meclizine.Uses
Meclizine+Pyridoxine is used for the prevention and treatment of symptoms of motion sickness, such as nausea, vomiting, dizziness, and headache. It may also be used to treat symptoms associated with vertigo.| Brand Name | Anosea Plus |
|---|---|
| Type | Tablet |
| Weight | 25 mg+50 mg |
| Generic | Meclizine + Pyridoxine |
| Manufacturer | Ibn Sina Pharmaceuticals Ltd. |
| Available in | English বাংলা |
Mechanism of Action
Meclizine hydrochloride works as an antihistamine to block the action of histamine, which is a chemical messenger responsible for vomiting and nausea. Pyridoxine (vitamin B6) helps to reduce the drowsiness associated with meclizine.How Long Does it Take to Work?
Meclizine+Pyridoxine usually starts working within 30 minutes of taking the medication. For the best results, take the medication 1 hour before travel.Absorption
Meclizine+Pyridoxine is rapidly absorbed from the gastrointestinal tract with peak plasma concentrations reached in 1 to 2 hours.Route of Elimination
Meclizine+Pyridoxine is mostly eliminated unchanged in the urine by glomerular filtration and tubular excretion.Dosage
Adult and Children 12 years of age & over:- Nausea and vomiting: 25-50 mg daily or as directed by a physician.
- Motion sickness: Take an initial dose of 25-50 mg, 1 hour prior to travel. May repeat the dose every 24 hours for the duration of the journey.
- Radiation sickness: 50 mg administered 2-12 hours prior to radiation treatment.
- Vertigo: 25-100 mg daily in divided doses.
- Prevention of nausea and vomiting associated with emergency contraceptive pill (ECP): 25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours.
Administration
Meclizine+Pyridoxine can be taken with or without food.Side Effects
Common side effects of Meclizine+Pyridoxine include dry mouth, fatigue, drowsiness, blurred vision, and difficulty focusing. Less common but more serious side effects include severe dizziness, fainting, skin rash, and difficulty breathing.Toxicity
Meclizine+Pyridoxine is not considered to be toxic at therapeutic doses. In cases of overdose, death is usually due to respiratory depression.Precautions
Meclizine+Pyridoxine should be used with caution in patients with glaucoma, liver or kidney impairment, asthma, breathing problems, or problems with urination. It may also interact with certain medications, so patients should inform their doctor of any medications they are taking prior to taking Meclizine+Pyridoxine.Interactions
Meclizine+Pyridoxine may interact with medications such as antihistamines, antidepressants, antipsychotics, and anticonvulsants. Patients should inform their health care provider of any medications they are taking prior to taking Meclizine+Pyridoxine.Disease Interaction
Meclizine+Pyridoxine should be used with caution in patients with glaucoma, liver or kidney impairment, asthma, breathing problems, or problems with urination.Drug Interaction
Meclizine+Pyridoxine may interact with medications such as antihistamines, antidepressants, antipsychotics, and anticonvulsants. Patients should inform their health care provider of any medications they are taking prior to taking Meclizine+Pyridoxine.Food Interactions
Meclizine+Pyridoxine may interact with certain foods and drinks, such as alcohol, which can increase the risk of side effects. Patients should inform their health care provider of any foods or drinks they are consuming prior to taking Meclizine+Pyridoxine.Pregnancy Use
Meclizine+Pyridoxine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Lactation Use
Meclizine+Pyridoxine is excreted in breast milk. Mothers taking Meclizine+Pyridoxine should be closely monitored for side effects in the infant.Acute Overdose
An acute overdose of Meclizine+Pyridoxine may result in sedation, drowsiness, and coma. Treatment is supportive.Contraindication
Meclizine+Pyridoxine is contraindicated in patients with hypersensitivity to meclizine hydrochloride or pyridoxine, or with a history of glaucoma or urinary retention.Use Directions
Meclizine+Pyridoxine should be taken as directed by the physician. The recommended dose is 1 tablet every 8-12 hours for adults and children 12 years of age or older, and 1 tablet 3 to 4 times daily for children 6-11 years of age. The maximum recommended daily dose is 6 tablets per day.Storage Conditions
Meclizine+Pyridoxine should be stored at room temperature (15-30°C/59-86°F) away from light and moisture.Volume of Distribution
The volume of distribution (Vd) of Meclizine+Pyridoxine is 0.26 L/kg.Half-Life
The half-life of Meclizine+Pyridoxine is 8-12 hours.Clearance
The clearance of Meclizine+Pyridoxine is 0.24 L/h/kg.See in details version Anosea Plus Tablet 25 mg+50 mg also Anosea Plus Tablet 25 mg+50 mg in bangla
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Some Frequently Asked Questions About Anosea Plus Tablet 25 mg+50 mg
1. What is Anosea Plus Tablet 25 mg+50 mg?
Anosea Plus Tablet 25 mg+50 mg is a combination medication used to treat nausea, vomiting, and dizziness associated with conditions like motion sickness and morning sickness during pregnancy. Meclizine is an antihistamine, while Pyridoxine is a form of Vitamin B6.
2. How does Anosea Plus Tablet 25 mg+50 mg work?
Meclizine works by blocking histamine receptors in the brain, which helps reduce symptoms of dizziness and nausea. Pyridoxine, or Vitamin B6, is believed to help reduce nausea, especially in pregnant women, by improving neurotransmitter function in the brain.
3. What is Anosea Plus Tablet 25 mg+50 mg used for?
This combination is primarily used for:
- Preventing and treating nausea and vomiting associated with motion sickness
- Managing morning sickness during pregnancy
- Alleviating dizziness or vertigo caused by inner ear problems
4. How should I take Anosea Plus Tablet 25 mg+50 mg?
Anosea Plus Tablet 25 mg+50 mg is typically taken orally, with or without food. The dosage may vary based on the condition being treated. Commonly, it is taken once or twice daily, but you should always follow your healthcare provider's instructions regarding dosage.
5. What are the common side effects of Anosea Plus Tablet 25 mg+50 mg?
Common side effects may include:
- Drowsiness or fatigue
- Dry mouth
- Headache
- Constipation
- Blurred vision
If any of these effects are bothersome or persist, consult your healthcare provider. Severe side effects like difficulty breathing or swelling require immediate medical attention.
6. Can I take Anosea Plus Tablet 25 mg+50 mg with other medications?
Anosea Plus Tablet 25 mg+50 mg can interact with other medications, particularly those that also cause drowsiness, such as other antihistamines, sedatives, or alcohol. Always inform your healthcare provider about any other medications you are taking to avoid harmful interactions.
7. Can I drive after taking Anosea Plus Tablet 25 mg+50 mg?
Meclizine may cause drowsiness, so it is advisable to avoid driving or operating heavy machinery until you understand how the medication affects you. Always assess your own alertness before engaging in activities that require full concentration.
8. Can Anosea Plus Tablet 25 mg+50 mg cause an allergic reaction?
Although rare, an allergic reaction to Anosea Plus Tablet 25 mg+50 mg can occur. Symptoms of an allergic reaction may include hives, swelling of the face or throat, difficulty breathing, and rash. If you experience any of these symptoms, seek emergency medical attention immediately.
9. Can Anosea Plus Tablet 25 mg+50 mg be taken during pregnancy?
Anosea Plus Tablet 25 mg+50 mg is commonly prescribed for managing morning sickness during pregnancy, as both ingredients are generally considered safe for use. However, it is essential to consult your healthcare provider before taking any medication during pregnancy.
10. Can Anosea Plus Tablet 25 mg+50 mg be taken while breastfeeding?
Meclizine passes into breast milk in small amounts. While it is generally considered safe to use during breastfeeding, you should consult your healthcare provider to ensure this combination is appropriate for you and your baby.
11. How should I store Anosea Plus Tablet 25 mg+50 mg?
Store Anosea Plus Tablet 25 mg+50 mg at room temperature, away from excessive heat and moisture. Keep it out of reach of children and in its original packaging to maintain effectiveness.
12. What should I do if I miss a dose of Anosea Plus Tablet 25 mg+50 mg?
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take the next dose at your regular time. Do not take extra medication to make up for a missed dose.
13. Can Anosea Plus Tablet 25 mg+50 mg be used for long-term treatment?
Anosea Plus Tablet 25 mg+50 mg is generally intended for short-term use to treat nausea, vomiting, and dizziness. Long-term use should only be done under the guidance of a healthcare provider to assess potential risks or side effects.
14. Can Anosea Plus Tablet 25 mg+50 mg cause drowsiness?
Yes, drowsiness is a common side effect of Meclizine. If you experience drowsiness, avoid activities that require full concentration, such as driving or using heavy machinery, until you are aware of how the medication affects you.
15. Is Anosea Plus Tablet 25 mg+50 mg safe for children?
Anosea Plus Tablet 25 mg+50 mg is generally not recommended for children under the age of 12 unless prescribed by a doctor. The safety and effectiveness for younger populations have not been established. Always consult a healthcare provider before giving this medication to children.
16. Can Anosea Plus Tablet 25 mg+50 mg be used for nausea and vomiting caused by chemotherapy?
Anosea Plus Tablet 25 mg+50 mg is not typically used for nausea and vomiting caused by chemotherapy. Other antiemetic drugs, such as ondansetron, are more commonly prescribed for chemotherapy-related nausea.
17. Can Anosea Plus Tablet 25 mg+50 mg be used for dizziness in pets?
Meclizine may sometimes be prescribed by veterinarians for dizziness in pets, but you should not give Anosea Plus Tablet 25 mg+50 mg to animals without consulting a veterinarian first.
18. How does Pyridoxine help with nausea during pregnancy?
Pyridoxine, or Vitamin B6, is commonly used to treat nausea and vomiting during pregnancy. It works by improving neurotransmitter function in the brain, which may help alleviate nausea, particularly in the early stages of pregnancy.
19. What is the difference between Anosea Plus Tablet 25 mg+50 mg and other anti-nausea medications?
Anosea Plus Tablet 25 mg+50 mg combines an antihistamine (Meclizine) with Vitamin B6 (Pyridoxine), whereas other anti-nausea medications like ondansetron work by blocking serotonin receptors. Pyridoxine is often specifically recommended for pregnant women, while Meclizine is more commonly used for motion sickness and vertigo.
20. What should I do if I overdose on Anosea Plus Tablet 25 mg+50 mg?
If you suspect an overdose of Anosea Plus Tablet 25 mg+50 mg, seek emergency medical help immediately. Symptoms of an overdose may include severe drowsiness, dry mouth, blurred vision, and difficulty breathing.
21. Does Anosea Plus Tablet 25 mg+50 mg interact with alcohol?
Alcohol can increase the sedative effects of Meclizine, leading to excessive drowsiness and dizziness. It is advisable to avoid drinking alcohol while taking this medication to reduce the risk of side effects.
22. Can Anosea Plus Tablet 25 mg+50 mg help with dizziness caused by low blood pressure?
Anosea Plus Tablet 25 mg+50 mg may help with dizziness, but it is not specifically designed to treat low blood pressure. If your dizziness is due to low blood pressure, consult your healthcare provider for the appropriate treatment.
23. Can Anosea Plus Tablet 25 mg+50 mg cause blurry vision?
Blurred vision is a possible side effect of Meclizine, particularly due to its anticholinergic properties. If you experience blurred vision, contact your healthcare provider for further guidance.
24. Can Anosea Plus Tablet 25 mg+50 mg be used for seasickness?
Yes, Anosea Plus Tablet 25 mg+50 mg can be used to prevent and treat seasickness, as it helps to alleviate symptoms like nausea and dizziness caused by motion.
25. Can I take Anosea Plus Tablet 25 mg+50 mg if I have a history of seizures?
If you have a history of seizures, it is essential to consult your healthcare provider before taking Anosea Plus Tablet 25 mg+50 mg. The combination may interact with other medications or conditions that affect seizure control.
26. How does Meclizine help with motion sickness?
Meclizine is an antihistamine that works by blocking the effects of histamine in the brain, which is responsible for symptoms of nausea, vomiting, and dizziness associated with motion sickness.
27. How long does it take for Anosea Plus Tablet 25 mg+50 mg to work?
Anosea Plus Tablet 25 mg+50 mg typically starts working within an hour of ingestion, with the effects lasting up to 24 hours. Individual responses may vary depending on the person and the condition being treated.
28. Can I stop taking Anosea Plus Tablet 25 mg+50 mg if my symptoms improve?
It’s important to follow your doctor’s recommendations when discontinuing Anosea Plus Tablet 25 mg+50 mg. Stopping suddenly may lead to a return of symptoms, so always consult your healthcare provider before stopping or adjusting your dosage.
29. Can I take Anosea Plus Tablet 25 mg+50 mg if I have asthma?
Meclizine is generally considered safe for individuals with asthma, but you should consult your doctor before taking it to ensure it does not interact with any asthma medications you are using.
30. Can Anosea Plus Tablet 25 mg+50 mg be used for motion sickness in children?
Anosea Plus Tablet 25 mg+50 mg is generally not recommended for children under the age of 12. Always consult your doctor before giving this medication to children.
31. Can Anosea Plus Tablet 25 mg+50 mg cause constipation?
Constipation is a possible side effect of Meclizine, which can occur due to its sedative effects. If you experience constipation, increase your fiber intake, drink plenty of water, and consult your healthcare provider if necessary.
32. Can Anosea Plus Tablet 25 mg+50 mg be used for vertigo?
Yes, Meclizine is commonly used to treat vertigo, particularly when caused by inner ear disorders. Pyridoxine helps reduce nausea associated with the condition.
33. Is Anosea Plus Tablet 25 mg+50 mg safe for elderly people?
Elderly individuals may be more sensitive to the sedative effects of Meclizine. Your doctor may adjust the dosage to minimize side effects like dizziness or drowsiness.
34. Does Anosea Plus Tablet 25 mg+50 mg cause drowsiness?
Yes, one of the common side effects of Meclizine is drowsiness. You should avoid engaging in activities that require alertness, such as driving, while taking this medication.
35. Can Anosea Plus Tablet 25 mg+50 mg help with nausea caused by pregnancy-related conditions other than morning sickness?
Anosea Plus Tablet 25 mg+50 mg may help with nausea related to pregnancy, including conditions like hyperemesis gravidarum. However, it is crucial to follow your doctor’s instructions on dosage and use.
36. What should I do if I experience severe side effects from Anosea Plus Tablet 25 mg+50 mg?
If you experience severe side effects like difficulty breathing, chest tightness, or swelling of the face, seek emergency medical help immediately.
37. How can I reduce the risk of side effects from Anosea Plus Tablet 25 mg+50 mg?
To minimize side effects, take the medication exactly as prescribed, avoid alcohol, and avoid driving or operating heavy machinery if you feel drowsy.
38. Can I take Anosea Plus Tablet 25 mg+50 mg with food?
Yes, Anosea Plus Tablet 25 mg+50 mg can be taken with or without food. However, if you experience stomach upset, taking it with food may help.
39. Can Anosea Plus Tablet 25 mg+50 mg interact with antidepressants?
Anosea Plus Tablet 25 mg+50 mg may interact with certain antidepressants, especially those that cause drowsiness. Always inform your healthcare provider about all medications you are taking.
40. Can Anosea Plus Tablet 25 mg+50 mg be used for nausea caused by motion sickness on airplanes?
Yes, Anosea Plus Tablet 25 mg+50 mg can help prevent and treat motion sickness symptoms while traveling on airplanes, including nausea and dizziness.
41. Can Anosea Plus Tablet 25 mg+50 mg be taken if I have a heart condition?
If you have a heart condition, consult your doctor before taking Anosea Plus Tablet 25 mg+50 mg, as it may have interactions with heart medications or affect your condition.
42. Can I drink coffee while taking Anosea Plus Tablet 25 mg+50 mg?
While there are no known interactions between coffee and Anosea Plus Tablet 25 mg+50 mg, excessive caffeine may exacerbate side effects like nervousness or restlessness. It’s best to consume coffee in moderation.
43. Can Anosea Plus Tablet 25 mg+50 mg be used to treat nausea from food poisoning?
Anosea Plus Tablet 25 mg+50 mg may help alleviate nausea from food poisoning, but it is not a treatment for the underlying cause. Hydration and rest are also essential, and you should consult a doctor if symptoms persist.
44. Does Anosea Plus Tablet 25 mg+50 mg help with dizziness caused by anxiety?
Anosea Plus Tablet 25 mg+50 mg is not intended for anxiety-induced dizziness. If anxiety is causing your dizziness, consult your doctor for appropriate treatment options.
45. How long can I take Anosea Plus Tablet 25 mg+50 mg for morning sickness?
The duration of treatment for morning sickness depends on your individual symptoms. It is typically used for short-term relief, but always consult your doctor if you need to take it for extended periods.
46. Can I take Anosea Plus Tablet 25 mg+50 mg if I am allergic to other antihistamines?
If you are allergic to other antihistamines, you should consult your healthcare provider before using Anosea Plus Tablet 25 mg+50 mg, as it may cause similar allergic reactions.
47. Can I use Anosea Plus Tablet 25 mg+50 mg for nausea from a hangover?
Anosea Plus Tablet 25 mg+50 mg may help with nausea, but it is not intended for hangover relief. Proper hydration and rest are the best ways to recover from a hangover.
48. Can I take Anosea Plus Tablet 25 mg+50 mg if I have diabetes?
Anosea Plus Tablet 25 mg+50 mg does not have direct effects on blood sugar, but you should consult your healthcare provider if you have diabetes, especially regarding other medications or potential side effects.
49. How should Anosea Plus Tablet 25 mg+50 mg be discontinued?
Discontinuing Anosea Plus Tablet 25 mg+50 mg should be done as per your healthcare provider’s instructions. Stopping abruptly is usually not recommended unless there are adverse effects.
50. Can Anosea Plus Tablet 25 mg+50 mg be used to treat dizziness caused by dehydration?
Anosea Plus Tablet 25 mg+50 mg may help manage dizziness, but dehydration must be treated with proper hydration. If dizziness persists, consult your doctor for further evaluation.
Dr. Alok Kumar Mandal
Cardiology (Heart Diseases, Hypertension & Rheumatic Fever) Specialist
Cardiac Surgeon in Khulna
