Amicard Plus Tablet

Introduction

Amlodipine besilate and Atenolol are two different medications that are prescribed together to treat high blood pressure. Amlodipine besilate is a calcium channel blocker and Atenolol is a beta blocker. When taken together, they work to lower blood pressure, reduce the risk of angina and heart attacks, and improve the quality of life for patients with high blood pressure.

Uses for

Amlodipine besilate and Atenolol are used to treat high blood pressure (hypertension). This medication is also used to reduce the risk of angina (chest pain) or heart attacks. It can also be used to reduce the risk of stroke.

Brand Name	Amicard Plus
Type	Tablet
Weight	5 mg+50 mg
Generic	Amlodipine Besilate + Atenolol
Manufacturer	Aexim Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Amlodipine besilate works by blocking the action of calcium on the heart and blood vessels, which reduces the workload on the heart and lowers blood pressure. Atenolol works by blocking the action of a certain type of nerve ending called a beta-2 receptor, which relaxes the blood vessels and reduces their resistance to blood flow.

How Long Does it Take to Work?

It usually takes 2-4 weeks for the full effects of this medication to be seen.

Absorption, Route of Elimination, Dosage, Administration

Amlodipine besilate is absorbed quickly through the intestines and Atenolol is absorbed slowly through the stomach. Both medications are metabolized in the liver and eliminated by the kidneys. The recommended initial dose for this combination is 2.5mg of Amlodipine besilate and 50mg of Atenolol, taken once daily. The doses can be adjusted according to the patient's response. It is important to take this medication exactly as prescribed by the doctor.

Side Effects

The most common side effects of this medication include dizziness, lightheadedness, headache, and nausea. Less common side effects include chest pain, fatigue, difficulty breathing, slowed heart rate, and irregular heartbeat.

Toxicity

This combination of medications is generally well-tolerated and not associated with a significant risk of toxicity. However, if taken in high doses, there may be an increased risk of side effects and toxicity.

Precautions

This medication should not be taken by anyone with kidney or liver disease, or by pregnant or breastfeeding women. It is important to tell the doctor about any other medications being taken or any medical conditions that may affect the way this medication works.

Interaction

This medication may interact with certain medications, so it is important to tell the doctor about any other medications being taken or any other medical conditions that may affect the way this medication works. Additionally, this medication may interact with certain foods, including grapefruit, so it is important to tell the doctor about any food allergies or other allergies that may affect the way this medication works.

Disease Interaction

This medication should not be taken by anyone with kidney or liver disease. It may also interact with certain medical conditions, so it is important to tell the doctor about any other medical conditions that may affect the way this medicaiton works.

Drug Interaction

This combination of medications may interact with certain medications, so it is important to tell the doctor about any other medications being taken. This includes prescription medications, over-the-counter medications, herbal supplements, and vitamins.

Food Interactions

This combination of medications may interact with certain foods, including grapefruit. It is important to tell the doctor about any food allergies or other allergies that may affect the way this medication works.

Pregnancy Use

It is not recommended that this medication be taken during pregnancy.

Lactation Use

It is not recommended that this medication be taken while breastfeeding.

Acute Overdose

In case of an overdose, seek medical help immediately. Symptoms of overdose may include abnormally low or high blood pressure, slowed heart rate, chest pain, and irregular heartbeat.

Contraindication

This medication should not be taken by anyone with kidney or liver disease, or anyone who is pregnant or breastfeeding.

Use Direction

This medication should be taken exactly as prescribed by the doctor. Do not increase the dose or take this medication more frequently than prescribed.