Alinix Powder for Suspension

Introduction

Alinix Powder for Suspension 100 mg/5 ml is an anthelmintic and anti-protozoal drug used to treat various parasitic infections such as giardiasis, cryptosporidiosis, and trichomoniasis, as well as helminthic infections like ascariasis and hookworm. It is available in oral and intravenous solutions.

Uses

Alinix Powder for Suspension 100 mg/5 ml is used to treat the following infections: Giardia lamblia, Cryptosporidium, Trichomonas vaginalis, Ascariasis, Enterobius vermicularis, Ancylostoma duodenale and Necator americanus.

Brand Name	Alinix
Type	Powder for Suspension
Weight	100 mg/5 ml
Generic	Nitazoxanide
Manufacturer	Healthcare Pharmaceuticals Ltd.
Available in	English বাংলা

Mechanism of Action

Alinix Powder for Suspension 100 mg/5 ml works by inhibiting the cytopathic effect of certain protozoa and helminths. It may works by interfering with DNA and RNA synthesis and by inhibiting the development of the parasites.

How Long Does it take to Work?

The time it takes for nitazoxanide to take effect varies and depends on the type of infection being treated. Generally, it begins to work within hours or days after ingestion, however, in order for full effectiveness, it may be necessary to continue taking nitazoxanide for several weeks or months.

Absorption

Alinix Powder for Suspension 100 mg/5 ml is absorbed quickly and completely when taken orally. The peak plasma concentration reaches within one hour of dosing.

Route of Elimination

Alinix Powder for Suspension 100 mg/5 ml is eliminated mainly through the feces. It is not known to be excreted in urine.

Dosage

Age 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days.
Age 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days.
Age 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days.

It is recommended to be administered with food. Alinix Powder for Suspension 100 mg/5 ml is available in tablet form in the following dosages:

Adult dose: 500 mg twice daily for three days.
Children 2-11 years: one 11-30 mg/kg/day in two divided doses (maximum 500 mg/day) three days duration or two divided doses (maximum 12 mg/kg/day) for five days.
Children 1-2 years: 11 mg/kg/day in two divided doses (maximum 500 mg/day) three days duration or two divided doses (maximum 12 mg/kg/day) for five days.

Administration

Alinix Powder for Suspension 100 mg/5 ml should be taken orally, with food or milk to reduce gastrointestinal side effects. It should be swallowed whole with a glass of water without crushing, splitting or chewing the tablet.

Side Effects

Common side effects of Alinix Powder for Suspension 100 mg/5 ml include: nausea, vomiting, abdominal pain, headache, dizziness, and diarrhea. Serious side effects are rare, but may include an increased risk of developing an infection, liver toxicity, or allergic reactions.

Toxicity

Alinix Powder for Suspension 100 mg/5 ml is generally considered to be safe at recommended doses. An acute overdose of nitazoxanide can lead to vomiting, diarrhea, tremors, increased heart rate, and confusion.

Precautions

Patients should inform their healthcare provider if they have a history of liver or kidney disease before taking Alinix Powder for Suspension 100 mg/5 ml. In addition, it is important to drink plenty of fluids while taking this medication to reduce the risk of dehydration.

Interactions

Alinix Powder for Suspension 100 mg/5 ml may interact with other medications, including antibiotics, antifungals, and anticonvulsants. It should not be taken with the anticonvulsants phenobarbital and primidone. Patients should inform their healthcare provider of all medications they are taking before starting Alinix Powder for Suspension 100 mg/5 ml.

Disease Interaction

Patients with a history of liver or kidney disease should not take Alinix Powder for Suspension 100 mg/5 ml. In addition, this medication should be used cautiously in patients with decreased kidney function, as it is excreted mainly by the kidneys.

Drug Interaction

Drugs that may interact with Alinix Powder for Suspension 100 mg/5 ml include antibiotics, antifungals, anticonvulsants, and antidiabetics. It should not be taken with the anticonvulsants phenobarbital and primidone. Patients should inform their doctor of all medications they are taking before starting Alinix Powder for Suspension 100 mg/5 ml.

Food Interactions

Alinix Powder for Suspension 100 mg/5 ml can be taken with or without food. Taking the medication with food may reduce gastrointestinal side effects.

Pregnancy Use

Alinix Powder for Suspension 100 mg/5 ml should not be used during pregnancy as it may cause harm to the unborn baby.

Lactation Use

Alinix Powder for Suspension 100 mg/5 ml is not known to pass into breast milk and can be used by breastfeeding mothers. However, caution should be exercised as there have not been sufficient studies to assess the safety of this drug in breastfeeding women.

Acute Overdose

An acute overdose of Alinix Powder for Suspension 100 mg/5 ml can result in vomiting, diarrhea, tremors, increased heart rate, and confusion. Treatment of an overdose usually involves supportive care, such as intravenous fluids to prevent dehydration and monitor vital signs.

Contraindication

Alinix Powder for Suspension 100 mg/5 ml should not be used in patients with a known hypersensitivity to the drug. It should also not be used in pregnant or breastfeeding women, or in patients with a history of liver or kidney disease.

Use Direction

Storage Condition

Alinix Powder for Suspension 100 mg/5 ml should be stored at room temperature away from light and moisture. Do not store in the bathroom. Keep out of the reach of children.