About AFM-Plus
AFM-Plus Ophthalmic Suspension
(Aristopharma Ltd.)
is a brand medicine
containing the generic
Fluorometholone + Gentamicin
.
Current listed price in Bangladesh: 5 ml drop: ৳ 110.00.
Medical information for AFM-Plus Ophthalmic Suspension 0.1%+0.3%
Uses, dosage, side effects, and safety details below apply to
AFM-Plus Ophthalmic Suspension 0.1%+0.3%
(generic:
Fluorometholone + Gentamicin).
This is general information — consult a doctor before use.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Introduction
Fluorometholone + gentamicin is a combination of medicines used to treat eye infections. Fluorometholone is a synthetic, steroidal glucocorticoid and an anti-inflammatory agent while gentamicin is an aminoglycoside antibiotic. This combination is used to treat bacterial infections of the eye such as eye conjunctivitis, keratitis, and anterior uveitis.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Uses
Fluorometholone + gentamicin is used to treat bacterial eye infections such as conjunctivitis, keratitis, and anterior uveitis. It is also used for other inflammatory and allergic conditions of the eye.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Mechanism of Action
Fluorometholone is a glucocorticoid which acts by mimicking the action of endogenous glucocorticoids like cortisol. It has anti-inflammatory and Vasoconstrictive action which helps in reducing swelling and pain. Gentamicin is an aminoglycoside antibiotic which kills bacteria by inhibiting bacterial protein synthesis and disrupting bacterial cell membranes.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: How Long Does It Take to Work?
Fluorometholone + gentamicin takes about two to four weeks to show improvement in the symptoms of eye infections.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Absorption
Fluorometholone is absorbed through the ocular route.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Route of Elimination
Fluorometholone is excreted through the renal route. Gentamicin is excreted through the renal route as well as through the ocular route.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Dosage
The dose of Fluorometholone + gentamicin depends on the condition of the patient. The usual recommended dose is 10 mg/ml (0.1%) Fluorometholone + 1 mg/ml (0.1%) gentamicin solution given 1-2 times a day.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Administration
Fluorometholone + gentamicin drops can be directly administered into the eye with the help of a dropper or it can be administered through a soft facial tissue placed over the eye.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Side Effects
The common side effects associated with Fluorometholone + gentamicin drops include irritation, burning, redness, and stinging in the eyes. Other rare side effects include headache, nausea, dizziness, blurred vision, and photophobia.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Toxicity
Fluorometholone + gentamicin, when taken in high doses, can be toxic to the body. There may be an increase in the risk of red cell destruction, renal damage, hearing impairment, and vertigo if taken in high doses.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Precaution
Fluorometholone + gentamicin should not be used in patients with a history of allergic reactions, eye infections, renal dysfunction, or with neurological disorders. It should also be used with caution in pregnant and lactating women.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Interaction
Fluorometholone + gentamicin may interact with other drugs like diuretics, anticoagulants, and drugs metabolized through the cytochrome P450 pathway.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Disease Interaction
Fluorometholone + gentamicin may interact with certain diseases like hypoglycemia, diabetes, hypothyroidism, glaucoma, and fungal infections.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Drug Interaction
Fluorometholone + gentamicin may interact with other drugs like antibiotics, antifungal drugs, antihistamines, and glucocorticoids.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Food Interactions
Fluorometholone + gentamicin may interact with certain food substances like alcohol, caffeine, iron, and vitamin supplements.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Pregnancy Use
Fluorometholone + gentamicin is not recommended during pregnancy as it may cause harmful side effects to the fetus.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Lactation Use
Fluorometholone + gentamicin is not recommended during lactation as it may cause harmful effects to the nursing infant.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Acute Overdose
In case of an acute overdose of Fluorometholone + gentamicin, the person should be immediately taken to a hospital and should seek medical attention.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Contraindication
Fluorometholone + gentamicin is contraindicated in patients with known hypersensitivity to steroids or gentamicin.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Dosage Direction
Fluorometholone + gentamicin should be applied as a thin film on the eye. The drops should not be applied more than 2 times a day and the eye should not be rinsed after application.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Storage Condition
Fluorometholone + gentamicin should be stored at room temperature.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Volume of Distribution
The volume of distribution of Fluorometholone + gentamicin is not known.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Half Life
The half-life of Fluorometholone + gentamicin is not known.
AFM-Plus Ophthalmic Suspension 0.1%+0.3%: Clearance
The clearance of Fluorometholone + gentamicin is not known.
Full generic monograph:
Fluorometholone + Gentamicin — uses, dosage & side effects
Medical review
Last reviewed:
30 Aug 2024
Medically reviewed by:
This is general information, not personal medical advice. Consult a doctor before taking any medicine.
Taking medicines without doctor's advice can cause long-term problems.
