Acelex Pediatric Drop 125 mg/1.25 ml 125 mg/1.25 ml Uses, Dosage, Side Effects & Price

Brand Name	Acelex
Type	Pediatric Drop
Weight	125 mg/1.25 ml
Generic	Cephalexin
Manufacturer	ACME Laboratories Ltd.

Brand Name

Acelex

Type

Pediatric Drop

Weight

125 mg/1.25 ml

Generic

Cephalexin

Manufacturer

ACME Laboratories Ltd.

About Acelex

Acelex Pediatric Drop (ACME Laboratories Ltd.) is a brand medicine containing the generic Cephalexin .

Introduction

Acelex Pediatric Drop 125 mg/1.25 ml is the first of the first generation cephalosporins. This antibiotic contains a beta lactam and a dihydrothiazide. Acelex Pediatric Drop 125 mg/1.25 ml is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.

Uses

Acelex Pediatric Drop 125 mg/1.25 ml is a first generation cephalosporin used to treat certain susceptible bacterial infections.

Acelex Pediatric Drop 125 mg/1.25 ml is indicated for the treatment of certain infections caused by susceptible bacteria. These infections include respiratory tract infections, otitis media, skin and skin structure infections, bone infections, and genitourinary tract infections.

Associated Conditions

Bone Infection
Genitourinary tract infection
Otitis Media (OM)
Respiratory Tract Infections (RTI)
Skin and skin structure infections
Acute Prostatitis

Pharmacodynamics

Acelex Pediatric Drop 125 mg/1.25 ml (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria through its inihibition of the cross linking reaction between N-acetyl muramicacid and N-acetylglucosamine in the cell wall, leading to cell lysis.

Mechanism of Action

Acelex Pediatric Drop 125 mg/1.25 ml is a first generation cephalosporin antibiotic. Cephalosporins contain a beta lactam and dihydrothiazide. Unlike penicillins, cephalosprins are more resistant to the action of beta lactamase. Acelex Pediatric Drop 125 mg/1.25 ml inhibits bacterial cell wall synthesis, leading breakdown and eventualy cell death.

Absorption

Well absorbed from the upper gastrointestinal tract with nearly 100% oral bioavailability. Acelex Pediatric Drop 125 mg/1.25 ml is not absorbed in the stomach but is absorbed in the upper intestine.

Patients taking 250mg of cephalexin reach a maximum plasma concentration of 7.7mcg/mL and patients taking 500mg reach 12.3mcg/mL.

Volume of Distribution

5.2-5.8L.

Protein Binding

Acelex Pediatric Drop 125 mg/1.25 ml is 10-15% bound to serum proteins including serum albumin.[A179053]

Route of Elimination

Acelex Pediatric Drop 125 mg/1.25 ml is over 90% excreted in the urine after 6 hours by glomerular filtration and tubular secretion with a mean urinary recovery of 99.3%. Acelex Pediatric Drop 125 mg/1.25 ml is unchanged in the urine.

Half Life

The half life of cephalexin is 49.5 minutes in a fasted state and 76.5 minutes with food though these times were not significantly different in the study.

Clearance

Clearance from one subject was 376mL/min.

Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. An overdose is generally managed through supportive treatment as diuresis, dialysis, hemodialysis, and charcoal hemoperfusion are not well studied in this case.

The oral median lethal dose of cephalexin in rats is >5000 mg/kg. The oral LD50 in a monkey is >1g/kg and the lowest dose causing a toxic effect in humans is 14mg/kg.

Acelex Pediatric Drop 125 mg/1.25 ml has not been shown to be harmful in pregnancy and is not associated with teratogeniticy. Acelex Pediatric Drop 125 mg/1.25 ml is present in breast milk, though infants may be exposed to Label The effects of breast milk exposure to cephalexin have not been established and so caution must be exercised and the risk and benefit of cephalexin use in breastfeeding must be weighed.

Acelex Pediatric Drop 125 mg/1.25 ml has not been studied for carcinogenicity or mutagenicity. Acelex Pediatric Drop 125 mg/1.25 ml has no affect on fertility in rats.

Food Interactions

Take with or without food.

Dosage

Adult:

The usual dose is 250 mg to 500 mg every 6 hour.
For skin and soft tissue infections, streptococcal pharyngitis and uncomplicated cystitis, in patients over 15 years of age: 500 mg of the drug may be administered every 12 hour.
In severe or deep seated infections the dose can be increased up to 3 g to 6 g daily.

Children: The dosage range is 25-100 mg/kg/day in divided doses to a maximum of 4 g daily

Children's Weight Recommended Dose:

10 kg (22 Ibs): 62.5 mg to 125 mg qid or 125 mg to 250 mg bid
20 kg (44 Ibs): 125 mg to 250 mg qid or 250 mg to 500 mg bid
40 kg (88 Ibs): 250 mg to 500 mg qid or 500 mg to 1 g bid

For streptococcal pharyngitis, skin and soft tissue infections and in patients over 1 year of age the total daily dose may be divided and administered every 12 hour. In the therapy of otitis media 75-100 mg/kg/day in four divided doses may be required. In the treatment of β haemolytic streptococcal infections a therapeutic dosage of the drug should be given at least for 10 days.

Frequently Asked Questions About Acelex Pediatric Drop 125 mg/1.25 ml

1. What is Acelex Pediatric Drop 125 mg/1.25 ml?

Acelex Pediatric Drop 125 mg/1.25 ml is an oral antibiotic in the cephalosporin class, specifically a first-generation cephalosporin. It is used to treat a variety of bacterial infections by interfering with the bacteria’s cell wall synthesis, leading to their death. It’s available under brand names like Keflex or as a generic in capsules, tablets, or liquid suspension.

2. What class of drug is Acelex Pediatric Drop 125 mg/1.25 ml?

Acelex Pediatric Drop 125 mg/1.25 ml belongs to the cephalosporin class of antibiotics, which are beta-lactam antibiotics similar to penicillins. As a first-generation cephalosporin, it’s particularly effective against gram-positive bacteria and some gram-negative bacteria.

3. How does Acelex Pediatric Drop 125 mg/1.25 ml work?

Acelex Pediatric Drop 125 mg/1.25 ml works by binding to penicillin-binding proteins (PBPs) in bacterial cell walls, inhibiting the final step of peptidoglycan synthesis. This weakens the cell wall, causing the bacteria to burst due to osmotic pressure. It’s bactericidal, meaning it kills bacteria rather than just stopping their growth.

4. What conditions does Acelex Pediatric Drop 125 mg/1.25 ml treat?

It treats infections caused by susceptible bacteria, including:

Skin infections: E.g., cellulitis, impetigo.
Respiratory tract infections: E.g., streptococcal pharyngitis (strep throat).
Urinary tract infections (UTIs): E.g., cystitis.
Bone infections: E.g., osteomyelitis.
Ear infections: E.g., otitis media.

It’s not effective against viral infections.

5. Is Acelex Pediatric Drop 125 mg/1.25 ml used for anything other than infections?

Its primary use is for bacterial infections. It’s occasionally used prophylactically (e.g., before dental procedures in patients with heart conditions to prevent endocarditis), but this is less common and depends on medical guidelines.

6. How is Acelex Pediatric Drop 125 mg/1.25 ml taken?

Acelex Pediatric Drop 125 mg/1.25 ml is taken orally as capsules, tablets, or a liquid suspension. It’s usually taken every 6–12 hours (2–4 times daily) with or without food, though food may reduce stomach upset. The liquid form should be shaken well before use.

7. What is the typical dosage for adults?

For adults, the usual dose is 250–500 mg every 6 hours or 500 mg every 12 hours, depending on the infection’s severity. For severe infections, up to 4 grams daily may be prescribed, split into doses. Treatment typically lasts 7–14 days.

8. What is the dosage for children?

For children, the dose is based on weight, typically 25–50 mg/kg/day, divided into 2–4 doses. For example, a 20 kg child might take 500–1000 mg daily. Higher doses (up to 100 mg/kg/day) may be used for severe infections, under medical supervision.

9. Can Acelex Pediatric Drop 125 mg/1.25 ml be taken with food?

Yes, it can be taken with or without food. Taking it with food may reduce stomach irritation, though it slightly slows absorption without affecting overall effectiveness.

10. What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it’s nearly time for the next dose. In that case, skip the missed dose and continue the schedule. Don’t double up, as this increases side effect risks.

11. How quickly does Acelex Pediatric Drop 125 mg/1.25 ml work?

Acelex Pediatric Drop 125 mg/1.25 ml starts killing bacteria within hours, but symptom relief may take 1–2 days. Full resolution depends on the infection type and severity, often requiring the full course (7–14 days) to prevent recurrence.

12. What are the common side effects?

Common side effects include:

Diarrhea: Due to gut flora disruption.
Nausea: Mild stomach upset.
Vomiting: Less common but possible.
Rash: Mild skin reactions.

These are usually temporary and mild.

13. What are the serious side effects?

Rare but serious side effects include:

Allergic reactions: Rash, swelling, or difficulty breathing.
Clostridium difficile colitis: Severe diarrhea from gut overgrowth.
Liver issues: Yellowing skin (jaundice).
Kidney problems: Reduced urine output.

Seek immediate medical help if these occur.

14. Why does Acelex Pediatric Drop 125 mg/1.25 ml cause diarrhea?

It disrupts normal gut bacteria, allowing overgrowth of harmful bacteria like *Clostridium difficile*. This can lead to loose stools or, rarely, severe colitis. Probiotics may help, but consult a doctor if diarrhea persists.

15. Can Acelex Pediatric Drop 125 mg/1.25 ml cause allergic reactions?

Yes, especially in those allergic to cephalosporins or penicillins (due to cross-reactivity). Symptoms include rash, itching, or anaphylaxis (rare). Stop use and seek help if severe reactions occur.

16. Who should not take Acelex Pediatric Drop 125 mg/1.25 ml?

It’s contraindicated for:

People allergic to cephalosporins: Or with penicillin allergy history (10% cross-reactivity risk).
Severe kidney disease: Without dose adjustment.

Caution is needed in these cases.

17. Is Acelex Pediatric Drop 125 mg/1.25 ml safe during pregnancy?

Yes, it’s classified as Category B by the FDA, meaning no evidence of fetal harm in animal studies. It’s often used in pregnancy for UTIs, but only under medical supervision.

18. Can I take Acelex Pediatric Drop 125 mg/1.25 ml while breastfeeding?

Yes, it passes into breast milk in small amounts but is generally safe. Monitor the infant for diarrhea or rash, and consult a doctor if concerned.

19. Does Acelex Pediatric Drop 125 mg/1.25 ml interact with other medications?

Yes, it may interact with:

Probenecid: Increases Acelex Pediatric Drop 125 mg/1.25 ml blood levels.
Metformin: May increase metformin levels.
Warfarin: Rarely enhances bleeding risk.

Inform your doctor of all medications.

20. Can I drink alcohol while taking Acelex Pediatric Drop 125 mg/1.25 ml?

Alcohol doesn’t directly interact with Acelex Pediatric Drop 125 mg/1.25 ml, but it may worsen side effects like nausea or delay healing. Moderate drinking is usually fine, but avoid excess.

21. Does Acelex Pediatric Drop 125 mg/1.25 ml cause weight gain?

No, it doesn’t affect metabolism or cause weight gain. Any weight change might relate to illness or recovery.

22. Can Acelex Pediatric Drop 125 mg/1.25 ml be taken at night?

Yes, it can be taken at any time, as long as doses are evenly spaced (e.g., every 6 6 or 12 hours). Nighttime dosing is fine if it fits your schedule.

23. How long do I need to take Acelex Pediatric Drop 125 mg/1.25 ml?

Complete the full course (usually 7–14 days), even if symptoms improve, to prevent bacterial resistance or recurrence. Stopping early can worsen the infection.

24. Can Acelex Pediatric Drop 125 mg/1.25 ml be stopped suddenly?

Don’t stop early unless advised by a doctor, as it may lead to incomplete treatment. There’s no withdrawal risk, but the infection could return.

25. Does Acelex Pediatric Drop 125 mg/1.25 ml affect blood sugar?

No, it doesn’t directly affect blood sugar. Any changes would be unrelated to the drug.

26. Can Acelex Pediatric Drop 125 mg/1.25 ml cause yeast infections?

Yes, by disrupting normal flora, it can increase the risk of vaginal yeast infections or oral thrush, especially in women or those with diabetes.

27. What should I avoid while taking Acelex Pediatric Drop 125 mg/1.25 ml?

Avoid skipping doses and unnecessary antibiotics to prevent resistance. No specific food or activity restrictions apply.

28. Can Acelex Pediatric Drop 125 mg/1.25 ml cause fatigue?

Fatigue isn’t a common side effect. If it occurs, it’s likely from the infection, not the drug.

29. Is Acelex Pediatric Drop 125 mg/1.25 ml safe for elderly patients?

Yes, but dose adjustments may be needed for reduced kidney function, common in older adults. Monitoring is key.

30. Does Acelex Pediatric Drop 125 mg/1.25 ml affect the liver?

Rarely, it may cause mild liver enzyme elevations, but significant liver damage is uncommon unless pre-existing liver disease exists.

31. Can Acelex Pediatric Drop 125 mg/1.25 ml be used in children?

Yes, it’s safe for children with weight-based dosing (25–100 mg/kg/day). It’s commonly used for ear or skin infections.

32. What’s the maximum dose of Acelex Pediatric Drop 125 mg/1.25 ml?

The maximum is 4 grams daily for adults, split into doses, though this is rare and reserved for severe infections.

33. Can Acelex Pediatric Drop 125 mg/1.25 ml cause dizziness?

Dizziness is rare and not a typical side effect. If it occurs, it might relate to dehydration or the infection.

34. How is Acelex Pediatric Drop 125 mg/1.25 ml different from other antibiotics?

Compared to penicillins, it’s broader-spectrum but less effective against some gram-negative bacteria than later cephalosporins. It’s oral and well-tolerated.

35. Can Acelex Pediatric Drop 125 mg/1.25 ml prevent infections?

It’s not typically used preventatively except in specific cases (e.g., endocarditis prophylaxis). It’s mainly for active infections.

36. Does Acelex Pediatric Drop 125 mg/1.25 ml affect cholesterol?

No, it has no impact on cholesterol levels.

37. Can Acelex Pediatric Drop 125 mg/1.25 ml be taken with other antibiotics?

Rarely, it’s combined with others for complex infections, but this is doctor-directed. Usually, it’s used alone.

38. What tests should I get while on Acelex Pediatric Drop 125 mg/1.25 ml?

For long-term or high-dose use, check kidney function and liver enzymes. Routine monitoring isn’t needed for short courses.

39. Can Acelex Pediatric Drop 125 mg/1.25 ml cause depression?

No, it doesn’t affect mood or the brain. Depression would be unrelated.

40. Is Acelex Pediatric Drop 125 mg/1.25 ml addictive?

No, it’s not addictive or habit-forming.

41. Can Acelex Pediatric Drop 125 mg/1.25 ml be crushed?

Capsules shouldn’t be crushed, but tablets can be if needed (check with a pharmacist). Liquid forms are available.

42. Does Acelex Pediatric Drop 125 mg/1.25 ml cause hair loss?

No, hair loss isn’t a side effect. Any loss would be from another cause.

43. Can Acelex Pediatric Drop 125 mg/1.25 ml be used for acne?

It’s not a first-line acne treatment but may be used for severe bacterial skin infections contributing to acne.

44. What’s the half-life of Acelex Pediatric Drop 125 mg/1.25 ml?

Its half-life is about 1 hour in healthy adults, longer with kidney impairment, requiring dose adjustments.

45. Can Acelex Pediatric Drop 125 mg/1.25 ml cause a rash?

Yes, a mild rash is possible, especially with sensitivity. A severe rash may signal an allergy—stop use and seek help.

46. Does Acelex Pediatric Drop 125 mg/1.25 ml affect exercise?

No direct effect, but if you’re unwell, exercise may feel harder. Side effects like diarrhea could also impact activity.

47. Can Acelex Pediatric Drop 125 mg/1.25 ml be taken with aspirin?

Yes, there’s no significant interaction. It’s safe to combine if needed.

48. Is Acelex Pediatric Drop 125 mg/1.25 ml expensive?

No, as a generic, it’s affordable, often costing $10–$20 for a course, depending on dose and region.

49. Can Acelex Pediatric Drop 125 mg/1.25 ml cause stomach pain?

Yes, mild stomach pain or nausea can occur, especially if taken on an empty stomach. Food may help.

50. How should Acelex Pediatric Drop 125 mg/1.25 ml be stored?

Store at room temperature (15–30°C or 59–86°F), away from moisture and heat. Keep liquid forms refrigerated if specified.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

Acelex Pediatric Drop